{"id":132394,"date":"2026-04-03T07:55:27","date_gmt":"2026-04-03T07:55:27","guid":{"rendered":"https:\/\/indogenmed.org\/resource\/viagra-how-it-works-benefits-guide\/"},"modified":"2026-09-20T07:02:31","modified_gmt":"2026-09-20T07:02:31","slug":"viagra-how-it-works-benefits-guide","status":"publish","type":"post","link":"https:\/\/indogenmed.org\/ja\/resource\/viagra-how-it-works-benefits-guide\/","title":{"rendered":"\u30d0\u30a4\u30a2\u30b0\u30e9\uff1a\u305d\u306e\u52b9\u679c\u3068\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u3064\u3044\u3066"},"content":{"rendered":"<div class=\"medical-review-disclosure\" style=\"background: #f9f9f9; padding: 15px; border-left: 5px solid #1E419B; margin-bottom: 25px; border-radius: 4px; font-size: 0.95em; line-height: 1.5;\">\n    <strong>\u533b\u7642\u76e3\u4fee\uff1a<\/strong> \u672c\u8a18\u4e8b\u306f2026\u5e744\u67083\u65e5\u306b<strong>\u5f53\u793e\u306e\u81e8\u5e8a\u30b5\u30dd\u30fc\u30c8\u30c1\u30fc\u30e0<\/strong>\u304c\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002\n<\/div>\n<p>\u300c\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4f55\u3092\u3059\u308b\u85ac\u306a\u306e\u304b\u300d\u3068\u7591\u554f\u306b\u601d\u3063\u305f\u3053\u3068\u304c\u3042\u308b\u65b9\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002<a href=\"https:\/\/indogenmed.org\/product\/viagra-100-mg-tablets\/\" target=\"_blank\" rel=\"noopener\">\u30d0\u30a4\u30a2\u30b0\u30e9<\/a>\u306f<a href=\"https:\/\/indogenmed.org\/medicine\/erectile-dysfunction\/\" target=\"_blank\" rel=\"noopener\">\u52c3\u8d77\u4e0d\u5168<\/a>\uff08ED\uff09\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u6700\u3082\u3088\u304f\u77e5\u3089\u308c\u305f\u85ac\u306e\u4e00\u3064\u3067\u3001\u4e16\u754c\u4e2d\u306e\u591a\u304f\u306e\u7537\u6027\u306e\u6027\u306e\u5065\u5eb7\u3092\u652f\u3048\u3066\u304d\u307e\u3057\u305f\u3002<\/p>\n<p>\u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3082\u3068\u3082\u3068ED\u6cbb\u7642\u306e\u305f\u3081\u306b\u4f5c\u3089\u308c\u305f\u85ac\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u6700\u521d\u306f\u5fc3\u81d3\u304c\u539f\u56e0\u306e\u80f8\u306e\u75db\u307f\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u3068\u3053\u308d\u304c\u30a6\u30a7\u30fc\u30eb\u30ba\u3067\u884c\u308f\u308c\u305f\u81e8\u5e8a\u8a66\u9a13\u3067\u3001\u53c2\u52a0\u8005\u304b\u3089\u52c3\u8d77\u304c\u6539\u5584\u3057\u305f\u3068\u3044\u3046\u601d\u3044\u304c\u3051\u306a\u3044\u526f\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u305f\u306e\u3067\u3059\u3002\u3053\u306e\u767a\u898b\u304cED\u6cbb\u7642\u85ac\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u958b\u767a\u306b\u3064\u306a\u304c\u308a\u3001\u73fe\u4ee3\u533b\u5b66\u306e\u5927\u304d\u306a\u8ee2\u6a5f\u3068\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306b\u306f<a href=\"https:\/\/indogenmed.org\/ja\/molecule\/sildenafil-citrate\/\" target=\"_blank\" rel=\"noopener\">\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb<\/a>\u304c\u542b\u307e\u308c\u3001\u8840\u7ba1\u3092\u7de9\u3081\u3066\u8840\u6d41\u3092\u6539\u5584\u3057\u307e\u3059\u3002PDE5\u963b\u5bb3\u85ac\u306b\u5206\u985e\u3055\u308c\u3001\u540c\u3058\u7cfb\u7d71\u306e\u85ac\u306f\u80ba\u52d5\u8108\u6027\u80ba\u9ad8\u8840\u5727\u75c7\u306a\u3069\u5225\u306e\u75c5\u6c17\u306b\u3082\u3001Revatio\u306a\u3069\u7570\u306a\u308b\u5546\u54c1\u540d\u3067\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u305d\u306e\u5f8c\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306f<a href=\"https:\/\/indogenmed.org\/product\/cialis-40mg-tablets\/\" target=\"_blank\" rel=\"noopener\">\u30b7\u30a2\u30ea\u30b9<\/a>\u3084<a href=\"https:\/\/indogenmed.org\/product\/levitra-20-mg-tablets\/\" target=\"_blank\" rel=\"noopener\">\u30ec\u30d3\u30c8\u30e9<\/a>\u306a\u3069\u985e\u4f3c\u306e\u85ac\u3068\u6bd4\u8f03\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u3089\u306f\u52b9\u304d\u59cb\u3081\u306e\u901f\u3055\u3001\u4f5c\u7528\u6642\u9593\u3001\u98df\u4e8b\u306e\u5f71\u97ff\u304c\u7570\u306a\u308a\u3001\u60a3\u8005\u3055\u3093\u306b\u8907\u6570\u306e\u9078\u629e\u80a2\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u52b9\u679c\u7684\u3067\u3059\u304c\u3001\u5b89\u5168\u306b\u4f7f\u3046\u3053\u3068\u304c\u5927\u5207\u3067\u3059\u3002\u785d\u9178\u85ac\u306a\u3069\u4e00\u90e8\u306e\u85ac\u3068\u4f75\u7528\u3059\u308b\u3068\u91cd\u5927\u306a\u5065\u5eb7\u88ab\u5bb3\u3092\u62db\u304f\u304a\u305d\u308c\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u5b89\u5168\u6027\u3084\u52b9\u679c\u304c\u7591\u308f\u3057\u3044\u507d\u9020\u54c1\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<p>\u3053\u306e\u30ac\u30a4\u30c9\u3067\u306f\u3001<a href=\"https:\/\/indogenmed.org\/ja\/resource\/what-viagra-feels-like\/\" target=\"_blank\" rel=\"noopener\">\u30d0\u30a4\u30a2\u30b0\u30e9\u304c\u3069\u306e\u3088\u3046\u306b\u50cd\u304f\u306e\u304b<\/a>\u3001\u4f55\u306b\u4f7f\u308f\u308c\u308b\u306e\u304b\u3001\u4f53\u306b\u3069\u3046\u5f71\u97ff\u3059\u308b\u306e\u304b\u3001\u305d\u3057\u3066\u5b89\u5168\u306a\u4f7f\u3044\u65b9\u3092\u8aac\u660e\u3057\u307e\u3059\u3002\u3054\u81ea\u8eab\u306e\u5065\u5eb7\u306b\u3064\u3044\u3066\u6b63\u3057\u304f\u5224\u65ad\u3059\u308b\u52a9\u3051\u306b\u306a\u308c\u3070\u5e78\u3044\u3067\u3059\u3002<\/p>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u3068\u306f\uff1f\u4f55\u306e\u305f\u3081\u306b\u4f7f\u3046\uff1f<\/h2>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\uff08\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\uff09\u306e\u6982\u8981<\/h3>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306e\u5546\u54c1\u540d\u3067\u3001\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc5\u578b\uff08PDE5\uff09\u963b\u5bb3\u85ac\u3068\u547c\u3070\u308c\u308b\u85ac\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5c5e\u3057\u307e\u3059\u3002\u4e3b\u306b\u52c3\u8d77\u4e0d\u5168\uff08ED\uff09\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u307e\u3059\u304c\u3001Revatio\u3068\u3044\u3046\u5546\u54c1\u540d\u3067\u80ba\u52d5\u8108\u6027\u80ba\u9ad8\u8840\u5727\u75c7\uff08PAH\uff09\u306b\u3082\u51e6\u65b9\u3055\u308c\u307e\u3059\u3002 <\/p>\n<p>\u96c6\u3081\u3089\u308c\u305f\u533b\u5b66\u30fb\u85ac\u5b66\u306e\u77e5\u898b\u306f\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306e\u5168\u4f53\u50cf\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u85ac\u306f\u8840\u7ba1\u3092\u7de9\u3081\u3066\u8840\u6d41\u3092\u6539\u5584\u3057\u3001\u6027\u6a5f\u80fd\u3068\u4e00\u90e8\u306e\u5fc3\u8840\u7ba1\u75be\u60a3\u306e\u4e21\u65b9\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002<\/p>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f1998\u5e74\u306bFDA\u306e\u627f\u8a8d\u3092\u53d7\u3051\u3001\u521d\u306e\u7d4c\u53e3ED\u6cbb\u7642\u85ac\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u4ee5\u6765\u3001\u4e16\u754c\u3067\u6700\u3082\u591a\u304f\u51e6\u65b9\u3055\u308c\u308b\u85ac\u306e\u4e00\u3064\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u4e3b\u306a\u533b\u7642\u7528\u9014<\/h3>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4e3b\u306b\u6b21\u306e\u76ee\u7684\u3067\u4f7f\u308f\u308c\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u52c3\u8d77\u4e0d\u5168\uff08ED\uff09\uff1a\u9670\u830e\u3078\u306e\u8840\u6d41\u3092\u6539\u5584\u3057\u3001\u6027\u884c\u70ba\u4e2d\u306b\u52c3\u8d77\u3092\u5f97\u3066\u7dad\u6301\u3067\u304d\u308b\u3088\u3046\u306b\u3057\u307e\u3059<\/li>\n<li>\u80ba\u52d5\u8108\u6027\u80ba\u9ad8\u8840\u5727\u75c7\uff08PAH\uff09\uff1a\u80ba\u306e\u8840\u7ba1\u3092\u7de9\u3081\u3001\u8840\u6db2\u5faa\u74b0\u3092\u6539\u5584\u3057\u307e\u3059<\/li>\n<\/ul>\n<p>\u3053\u308c\u4ee5\u5916\u306b\u3082\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306f\u85ac\u7269\u52d5\u614b\uff08\u4f53\u5185\u3067\u306e\u52d5\u304d\uff09\u306e\u9762\u304b\u3089\u7814\u7a76\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3069\u308c\u304f\u3089\u3044\u901f\u304f\u5438\u53ce\u3055\u308c\u3001\u3069\u308c\u304f\u3089\u3044\u4f5c\u7528\u3057\u3001\u3069\u306e\u3088\u3046\u306b\u6392\u51fa\u3055\u308c\u308b\u304b\u3068\u3044\u3046\u70b9\u3067\u3059\u3002<\/p>\n<p>\u901a\u5e38\u306f\u7d4c\u53e3\u3067\u670d\u7528\u3057\u3001<a href=\"https:\/\/indogenmed.org\/ja\/resource\/sildenafil-onset-duration\/\" target=\"_blank\" rel=\"noopener\">30\u301c60\u5206<\/a>\u3067\u52b9\u304d\u59cb\u3081\u307e\u3059\u3002<\/p>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4f53\u5185\u3067\u4f55\u3092\u3057\u3066\u3044\u308b\uff1f<\/h2>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u6709\u52b9\u6210\u5206\u306f\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u30af\u30a8\u30f3\u9178\u5869\u3067\u3001\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc5\u578b\uff08PDE5\uff09\u3068\u3044\u3046\u9175\u7d20\u3092\u5f37\u529b\u304b\u3064\u9078\u629e\u7684\u306b\u963b\u5bb3\u3057\u307e\u3059\u3002<\/p>\n<p>\u4f53\u5185\u3067\u306e\u4e3b\u306a\u50cd\u304d\u306f\u3001\u8840\u7ba1\u306e\u62e1\u5f35\u3068\u5e73\u6ed1\u7b4b\u306e\u7dca\u5f35\u3092\u8abf\u7bc0\u3059\u308b\u4e00\u9178\u5316\u7a92\u7d20\u30fb\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178\uff08NO-cGMP\uff09\u306e\u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u306b\u4f5c\u7528\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n<p>\u5927\u5207\u306a\u306e\u306f\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u304c\u76f4\u63a5\u52c3\u8d77\u3092\u8d77\u3053\u3059\u308f\u3051\u3067\u306f\u306a\u3044\u3068\u3044\u3046\u70b9\u3067\u3059\u3002\u6027\u7684\u8208\u596e\u306b\u5bfe\u3059\u308b\u4f53\u306e\u81ea\u7136\u306a\u53cd\u5fdc\u3092\u5f37\u3081\u3001\u6301\u7d9a\u3055\u305b\u308b\u85ac\u3067\u3059\u3002\u52b9\u679c\u3092\u5f97\u308b\u306b\u306f\u3001\u4e00\u9178\u5316\u7a92\u7d20\u306e\u653e\u51fa\u3092\u4fc3\u3059\u6027\u7684\u523a\u6fc0\u304c\u307e\u305a\u5fc5\u8981\u3067\u3059\u3002<\/p>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\u304c\u52c3\u8d77\u3092\u52a9\u3051\u308b\u4ed5\u7d44\u307f<\/h3>\n<ul>\n<li><strong>\u53cd\u5fdc\u306e\u59cb\u307e\u308a<\/strong>: \u6027\u7684\u523a\u6fc0\u3092\u53d7\u3051\u308b\u3068\u3001\u9670\u830e\u306e\u795e\u7d4c\u7d42\u672b\u3068\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u304c\u4e00\u9178\u5316\u7a92\u7d20\uff08NO\uff09\u3092\u653e\u51fa\u3057\u307e\u3059\u3002<\/li>\n<li><strong>cGMP\u306e\u7523\u751f<\/strong>: \u4e00\u9178\u5316\u7a92\u7d20\u304c\u30b0\u30a2\u30cb\u30eb\u9178\u30b7\u30af\u30e9\u30fc\u30bc\u3068\u3044\u3046\u9175\u7d20\u3092\u6d3b\u6027\u5316\u3057\u3001\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\uff08GTP\uff09\u3092\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178\uff08cGMP\uff09\u306b\u5909\u63db\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u7b4b\u8089\u306e\u5f1b\u7de9<\/strong>: cGMP\u304c\u5897\u3048\u308b\u3068\u3001\u9670\u830e\u6d77\u7dbf\u4f53\u3068\u7d30\u52d5\u8108\u58c1\u306e\u5e73\u6ed1\u7b4b\u7d30\u80de\u306b\u7de9\u3080\u3088\u3046\u4fe1\u53f7\u304c\u9001\u3089\u308c\u307e\u3059\u3002<\/li>\n<li><strong>\u8840\u6d41\u306e\u5897\u52a0<\/strong>: \u3053\u306e\u5f1b\u7de9\u306b\u3088\u308a\u9670\u830e\u3078\u306e\u8840\u6d41\u304c\u5927\u304d\u304f\u5897\u3048\u3001\u6d1e\u69d8\u8840\u7ba1\u304c\u6e80\u305f\u3055\u308c\u3066\u81a8\u3089\u307f\u307e\u3059\u3002<\/li>\n<li><strong>\u8840\u6db2\u306e\u4fdd\u6301<\/strong>: \u81a8\u3089\u3093\u3060\u6d1e\u69d8\u8840\u7ba1\u304c\u3001\u901a\u5e38\u306f\u8840\u6db2\u3092\u6392\u51fa\u3059\u308b\u9759\u8108\u3092\u5727\u8feb\u3057\u3001\u8840\u6db2\u3092\u9589\u3058\u8fbc\u3081\u3066\u786c\u3044\u52c3\u8d77\u3092\u4f5c\u308a\u3001\u7dad\u6301\u3057\u307e\u3059\u3002<\/li>\n<li><strong>PDE5\u963b\u5bb3\u306e\u5f79\u5272<\/strong>: \u901a\u5e38\u306fPDE5\u3068\u3044\u3046\u9175\u7d20\u304ccGMP\u3092\u5206\u89e3\u3057\u3001\u5e73\u6ed1\u7b4b\u304c\u518d\u3073\u53ce\u7e2e\u3057\u3066\u52c3\u8d77\u304c\u304a\u3055\u307e\u308a\u307e\u3059\u3002\u30d0\u30a4\u30a2\u30b0\u30e9\u306fPDE5\u3092\u963b\u5bb3\u3057\u3001cGMP\u3092\u84c4\u7a4d\u3055\u305b\u3066\u5e73\u6ed1\u7b4b\u306e\u5f1b\u7de9\u3092\u9577\u304f\u4fdd\u3061\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\u3092\u98f2\u3093\u3060\u3042\u3068\u306b\u8d77\u3053\u308b\u3053\u3068<\/h3>\n<p>\t\t\t\u52c3\u8d77\u7d44\u7e54\u4ee5\u5916\u306b\u3082\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306fPDE5\u304c\u5b58\u5728\u3059\u308b\u5225\u306e\u5668\u5b98\u306b\u3082\u4f5c\u7528\u3057\u307e\u3059\u3002\u80ba\u306e\u8840\u7ba1\u3092\u7de9\u3081\u3066\u8840\u5727\u3092\u4e0b\u3052\u3001\u904b\u52d5\u80fd\u529b\u3092\u9ad8\u3081\u308b\u305f\u3081\u3001\u80ba\u52d5\u8108\u6027\u80ba\u9ad8\u8840\u5727\u75c7\uff08PAH\uff09\u306e\u6cbb\u7642\u3067\u9078\u629e\u7684\u306a\u80ba\u8840\u7ba1\u62e1\u5f35\u85ac\u3068\u3057\u3066\u4f7f\u308f\u308c\u307e\u3059\u3002\u5065\u5eb7\u306a\u4eba\u306e\u591a\u304f\u3067\u306f\u3001\u5168\u8eab\u306e\u8840\u5727\u304c\u4e00\u6642\u7684\u306b\u308f\u305a\u304b\u306b\u4e0b\u304c\u308a\u3001\u5e73\u5747\u30678.4\/5.5mmHg\u7a0b\u5ea6\u3067\u3059\u3002\u307e\u305f\u3001\u76ee\u304c\u5149\u3092\u51e6\u7406\u3059\u308b\u969b\u306b\u95a2\u308f\u308b\u7db2\u819c\u306e\u9175\u7d20PDE6\u306b\u3082\u308f\u305a\u304b\u306b\u4f5c\u7528\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u8996\u754c\u304c\u9752\u307f\u304c\u304b\u308b\uff08\u9752\u8996\u75c7\uff09\u3001\u5149\u306b\u654f\u611f\u306b\u306a\u308b\u3068\u3044\u3063\u305f\u4e00\u6642\u7684\u306a\u8996\u899a\u306e\u5909\u5316\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4e3b\u306b\u809d\u81d3\u306e\u30b7\u30c8\u30af\u30ed\u30e0P450\u7cfb\u3067\u4ee3\u8b1d\u3055\u308c\u3001\u7d42\u672b\u534a\u6e1b\u671f\u306f\u304a\u3088\u305d4\u6642\u9593\u3067\u3059\u3002<\/p>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u4f5c\u7528\u6a5f\u5e8f<\/h2>\n<p>\u5316\u5b66\u7684\u306b\u306f\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u30af\u30a8\u30f3\u9178\u5869\u3068\u547c\u3070\u308c\u308b\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3001\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc5\u578b\uff08PDE5\uff09\u963b\u5bb3\u85ac\u306e\u4ee3\u8868\u7684\u306a\u85ac\u3067\u3059\u3002\u4e3b\u306a\u4f5c\u7528\u6a5f\u5e8f\u306f\u3001PDE5\u3068\u3044\u3046\u9175\u7d20\u3092\u9078\u629e\u7684\u304b\u3064\u5f37\u529b\u306b\u963b\u5bb3\u3057\u3001\u6027\u7684\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u4f53\u306e\u81ea\u7136\u306a\u53cd\u5fdc\u3092\u9ad8\u3081\u308b\u3053\u3068\u3067\u3059<\/p>\n<h3>\u52c3\u8d77\u304c\u8d77\u3053\u308b\u81ea\u7136\u306a\u6d41\u308c<\/h3>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u50cd\u304d\u3092\u7406\u89e3\u3059\u308b\u306b\u306f\u3001\u4e00\u9178\u5316\u7a92\u7d20\uff08NO\uff09\u3068\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178\uff08cGMP\uff09\u306e\u30b7\u30b0\u30ca\u30eb\u7d4c\u8def\u3092\u898b\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059<\/p>\n<ul>\n<li><strong>\u4e00\u9178\u5316\u7a92\u7d20\u306e\u653e\u51fa<\/strong>: \u6027\u7684\u8208\u596e\u304c\u8d77\u3053\u308b\u3068\u3001\u9670\u830e\u306e\u795e\u7d4c\u306e\u50cd\u304d\u3068\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u304c\u6d77\u7dbf\u4f53\u306b\u4e00\u9178\u5316\u7a92\u7d20\u3092\u653e\u51fa\u3057\u307e\u3059<\/li>\n<li><strong>cGMP\u306e\u7523\u751f<\/strong>: NO\u304c\u30b0\u30a2\u30cb\u30eb\u9178\u30b7\u30af\u30e9\u30fc\u30bc\u3092\u6d3b\u6027\u5316\u3057\u3001\u30b0\u30a2\u30ce\u30b7\u30f3\u4e09\u30ea\u30f3\u9178\uff08GTP\uff09\u3092\u91cd\u8981\u306a\u4e8c\u6b21\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc\u3067\u3042\u308bcGMP\u306b\u5909\u3048\u307e\u3059<\/li>\n<li><strong>\u5e73\u6ed1\u7b4b\u306e\u5f1b\u7de9<\/strong>: cGMP\u304c\u30d7\u30ed\u30c6\u30a4\u30f3\u30ad\u30ca\u30fc\u30bcG\u3092\u6d3b\u6027\u5316\u3057\u3001\u4e00\u9023\u306e\u53cd\u5fdc\u306b\u3088\u3063\u3066\u7d30\u80de\u5185\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u4f4e\u4e0b\u3057\u307e\u3059<\/li>\n<li><strong>\u8840\u6d41\u3068\u5727\u529b<\/strong>: \u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u4e0b\u304c\u308b\u3053\u3068\u3067\u8840\u7ba1\u5e73\u6ed1\u7b4b\u304c\u7de9\u307f\u3001\u8840\u6db2\u304c\u6d77\u7dbf\u4f53\u306e\u6d1e\u69d8\u8840\u7ba1\u306b\u6d41\u308c\u8fbc\u307f\u307e\u3059<\/li>\n<\/ul>\n<p>\u7d44\u7e54\u304c\u81a8\u3089\u3080\u3068\u9670\u830e\u306e\u9759\u8108\u304c\u5727\u8feb\u3055\u308c\u3001\u8840\u6db2\u304c\u9589\u3058\u8fbc\u3081\u3089\u308c\u3066\u52c3\u8d77\u304c\u7dad\u6301\u3055\u308c\u307e\u3059<\/p>\n<h3>PDE5\u3068\u3044\u3046\u9175\u7d20\u306e\u5f79\u5272<\/h3>\n<p>PDE5\u306f\u3053\u306e\u6d41\u308c\u3092\u81ea\u7136\u306b\u7d42\u308f\u3089\u305b\u308b\u5f79\u5272\u3092\u62c5\u3044\u307e\u3059\u3002\u751f\u7406\u7684\u306b\u306f\u3001cGMP\u3092\u52a0\u6c34\u5206\u89e3\u3057\u3066\u4e0d\u6d3b\u6027\u306a5&#8242;-GMP\u306b\u5909\u3048\u307e\u3059\u3002<\/p>\n<p>cGMP\u304c\u5206\u89e3\u3055\u308c\u308b\u3068\u7d30\u80de\u5185\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u518d\u3073\u4e0a\u6607\u3057\u3001\u5e73\u6ed1\u7b4b\u304c\u53ce\u7e2e\u3057\u3066\u9670\u830e\u306f\u5143\u306e\u72b6\u614b\u306b\u623b\u308a\u307e\u3059\u3002PDE5\u306f\u9670\u830e\u6d77\u7dbf\u4f53\u3068\u80ba\u8840\u7ba1\u306b\u6700\u3082\u591a\u304f\u5b58\u5728\u3059\u308b\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u3067\u3059<\/p>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u4f5c\u7528\u6a5f\u5e8f<br \/>\n<\/h3>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3001PDE5\u3068\u3044\u3046\u9175\u7d20\u3092\u5f37\u529b\u304b\u3064\u9078\u629e\u7684\u306b\u3001\u305d\u3057\u3066\u7af6\u5408\u7684\u306b\u963b\u5bb3\u3057\u307e\u3059\u3002<\/p>\n<ul>\n<li><strong>\u5206\u5b50\u30ec\u30d9\u30eb\u306e\u6a21\u5023<\/strong>: \u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u69cb\u9020\u306f\u3001cGMP\u306e\u30b0\u30a2\u30cb\u30f3\u5869\u57fa\u3092\u6a21\u5023\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u305f\u3081PDE5\u9175\u7d20\u306e\u89e6\u5a92\u90e8\u4f4d\uff08\u3044\u308f\u3086\u308b\u300cQ\u30dd\u30b1\u30c3\u30c8\u300d\uff09\u306b\u7d50\u5408\u3057\u3001\u672c\u6765cGMP\u304c\u5206\u89e3\u3055\u308c\u308b\u5834\u6240\u3092\u5360\u6709\u3067\u304d\u307e\u3059\u3002<\/li>\n<li><strong>cGMP\u306e\u84c4\u7a4d<\/strong>: cGMP\u3092\u5206\u89e3\u3059\u308b\u9175\u7d20\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u3067\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3053\u306e\u4e8c\u6b21\u30e1\u30c3\u30bb\u30f3\u30b8\u30e3\u30fc\u3092\u84c4\u7a4d\u3055\u305b\u3001\u3088\u308a\u9577\u304f\u4fdd\u3061\u307e\u3059\u3002<\/li>\n<li>\u5f1b\u7de9\u306e\u6301\u7d9a\uff1acGMP\u304c\u9ad8\u3044\u72b6\u614b\u304c\u7d9a\u304f\u3053\u3068\u3067\u5e73\u6ed1\u7b4b\u306f\u7de9\u3093\u3060\u307e\u307e\u3001\u8840\u7ba1\u306f\u5e83\u304c\u3063\u305f\u307e\u307e\u3068\u306a\u308a\u3001\u52c3\u8d77\u304c\u5f37\u307e\u308a\u9577\u304f\u7d9a\u304d\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u91cd\u8981\u306a\u6ce8\u610f\u70b9<\/p>\n<ul>\n<li><strong>\u8208\u596e\u304c\u5fc5\u8981\u306a\u3053\u3068<\/strong>: \u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u5a9a\u85ac\u3067\u306f\u306a\u304f\u3001\u6027\u7684\u523a\u6fc0\u304c\u306a\u3051\u308c\u3070\u52c3\u8d77\u306f\u8d77\u3053\u308a\u307e\u305b\u3093\u3002cGMP\u306e\u5206\u89e3\u3092\u9632\u3050\u3053\u3068\u3067\u50cd\u304f\u305f\u3081\u3001\u8208\u596e\u6642\u306b\u306e\u307f\u8d77\u3053\u308b\u4e00\u9178\u5316\u7a92\u7d20\u306e\u653e\u51fa\u304c\u6700\u521d\u306b\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u6b63\u306e\u30d5\u30a3\u30fc\u30c9\u30d0\u30c3\u30af<\/strong>: \u8208\u5473\u6df1\u3044\u3053\u3068\u306b\u3001cGMP\u304c\u5897\u3048\u3066PDE5\u306e\u8abf\u7bc0\u30c9\u30e1\u30a4\u30f3\u306e\u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u90e8\u4f4d\u306b\u7d50\u5408\u3059\u308b\u3068\u3001\u9175\u7d20\u306e\u69cb\u9020\u304c\u5909\u5316\u3057\u3001\u89e6\u5a92\u90e8\u4f4d\u306e\u30d0\u30a4\u30a2\u30b0\u30e9\u306b\u5bfe\u3059\u308b\u89aa\u548c\u6027\u304c\u9ad8\u307e\u308a\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u6027\u7684\u8208\u596e\u304c\u5f37\u3044\u3068\u304d\u307b\u3069\u85ac\u306e\u963b\u5bb3\u52b9\u679c\u306f\u5f37\u307e\u308b\u306e\u3067\u3059<\/li>\n<\/ul>\n<h2>\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u304cPDE5\u3092\u963b\u5bb3\u3059\u308b\u4ed5\u7d44\u307f<\/h2>\n<p>\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\uff08\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u6709\u52b9\u6210\u5206\uff09\u306f\u3001\u7af6\u5408\u963b\u5bb3\u3068\u3044\u3046\u5f62\u3067\u30db\u30b9\u30db\u30b8\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc5\uff08PDE5\uff09\u3092\u963b\u5bb3\u3057\u307e\u3059\u3002\u9175\u7d20\u306e\u6d3b\u6027\u90e8\u4f4d\u3092\u7269\u7406\u7684\u306b\u5360\u6709\u3057\u3001\u672c\u6765\u306e\u57fa\u8cea\u3067\u3042\u308b\u74b0\u72b6\u30b0\u30a2\u30ce\u30b7\u30f3\u4e00\u30ea\u30f3\u9178\uff08cGMP\uff09\u304c\u7d50\u5408\u3067\u304d\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u306e\u3067\u3059\u3002<\/p>\n<p>\u305d\u306e\u52b9\u679c\u306f\u5206\u5b50\u30ec\u30d9\u30eb\u306e\u6a21\u5023\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306f\u4e8c\u74b0\u5f0f\u306e\u30d4\u30e9\u30be\u30ed\u30d4\u30ea\u30df\u30b8\u30ce\u30f3\u9aa8\u683c\u3092\u6301\u3061\u3001cGMP\u306e\u30b0\u30a2\u30cb\u30f3\u5869\u57fa\u306e\u69cb\u9020\u7684\u306a\u985e\u4f3c\u4f53\u3068\u3057\u3066\u50cd\u304d\u307e\u3059\u3002<\/p>\n<p>\u5206\u5b50\u306e\u5468\u8fba\u306b\u3042\u308b\u7f6e\u63db\u57fa\u306f\u3001cGMP\u306e\u30ea\u30dc\u30fc\u30b9\u3084\u30ea\u30f3\u9178\u57fa\u306e\u4f4d\u7f6e\u3092\u518d\u73fe\u3059\u308b\u3088\u3046\u306b\u914d\u7f6e\u3055\u308c\u3066\u304a\u308a\u3001\u85ac\u304c\u9175\u7d20\u306e\u89e6\u5a92\u30dd\u30b1\u30c3\u30c8\u306b\u3074\u305f\u308a\u3068\u53ce\u307e\u308a\u307e\u3059\u3002<\/p>\n<h3>\u3053\u306e\u7cbe\u5bc6\u306a\u963b\u5bb3\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u91cd\u8981\u306a\u539f\u5b50\u30ec\u30d9\u30eb\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u3063\u3066\u4fdd\u305f\u308c\u3066\u3044\u307e\u3059\u3002<\/h3>\n<ul>\n<li><strong>\u30b0\u30eb\u30bf\u30df\u30f3\u306e\u30b9\u30a4\u30c3\u30c1<\/strong>: \u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306f\u3001\u4e0d\u5909\u306e\u6b8b\u57faGln817\u3068\u91cd\u8981\u306a\u4e8c\u5ea7\u6c34\u7d20\u7d50\u5408\u3092\u4f5c\u308a\u307e\u3059\u3002\u3053\u308c\u306fcGMP\u9078\u629e\u7684\u306a\u9175\u7d20\u306b\u7279\u5fb4\u7684\u306a\u76f8\u4e92\u4f5c\u7528\u3067\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u3092\u89e6\u5a92\u90e8\u4f4d\u306b\u3057\u3063\u304b\u308a\u56fa\u5b9a\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u758e\u6c34\u6027\u306b\u3088\u308b\u56fa\u5b9a<\/strong>: \u963b\u5bb3\u85ac\u306f\u758e\u6c34\u6027\u306e\u6b8b\u57fa\u306b\u631f\u307f\u8fbc\u307e\u308c\u3001\u7279\u306bPhe820\u3068\u306e\u03c0\u30b9\u30bf\u30c3\u30ad\u30f3\u30b0\u76f8\u4e92\u4f5c\u7528\u304c\u50cd\u304d\u307e\u3059\u3002\u3055\u3089\u306bTyr612\u3001His613\u3001Val782\u3001Phe786\u3068\u3044\u3063\u305f\u4fdd\u5b58\u3055\u308c\u305f\u6b8b\u57fa\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u304c\u5b89\u5b9a\u5316\u306b\u5bc4\u4e0e\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u758e\u6c34\u6027\u30dd\u30b1\u30c3\u30c8<\/strong>: \u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306e\u30a8\u30c8\u30ad\u30b7\u30d5\u30a7\u30cb\u30eb\u57fa\u306f\u5c0f\u3055\u306a\u758e\u6c34\u6027\u30dd\u30b1\u30c3\u30c8\uff08Glu780\u3001Ala783\u3001Met816\u306a\u3069\u306e\u6b8b\u57fa\u304b\u3089\u306a\u308b\uff09\u306b\u53ce\u307e\u308a\u3001\u7d50\u5408\u89aa\u548c\u6027\u3092\u5927\u304d\u304f\u9ad8\u3081\u307e\u3059\u3002<\/li>\n<\/ul>\n<p>\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306e\u963b\u5bb3\u6a5f\u69cb\u3092\u7279\u5fb4\u3065\u3051\u308b\u306e\u304c\u3001\u9175\u7d20\u69cb\u9020\u3001\u7279\u306bH\u30eb\u30fc\u30d7\uff08\u6b8b\u57fa660\u301c683\uff09\u3068\u547c\u3070\u308c\u308b\u90e8\u5206\u306b\u8d77\u3053\u308b\u5927\u304d\u306a\u69cb\u9020\u5909\u5316\u3067\u3059\u3002<\/p>\n<p>\u4f55\u3082\u7d50\u5408\u3057\u3066\u3044\u306a\u3044\u72b6\u614b\u3067\u306f\u3001\u9175\u7d20\u306e\u6d3b\u6027\u90e8\u4f4d\u306f\u57fa\u8cea\u304c\u5165\u308c\u308b\u3088\u3046\u306b\u300c\u958b\u3044\u3066\u300d\u3044\u307e\u3059\u3002\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u304c\u7d50\u5408\u3059\u308b\u3068\u3001H\u30eb\u30fc\u30d7\u306f\u6700\u592724\u00c5\u52d5\u304d\u3001\u6d3b\u6027\u90e8\u4f4d\u306f\u300c\u9589\u3058\u305f\u300d\u30dd\u30b1\u30c3\u30c8\u306b\u5909\u308f\u308a\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u5909\u5316\u306b\u3088\u3063\u3066\u963b\u5bb3\u85ac\u306f\u5185\u90e8\u306b\u9589\u3058\u8fbc\u3081\u3089\u308c\u3001\u305d\u306e\u5834\u306b\u300c\u56fa\u5b9a\u300d\u3055\u308c\u307e\u3059\u3002\u3053\u308c\u304c\u85ac\u306e\u5f37\u3044\u52b9\u679c\u3068\u3086\u3063\u304f\u308a\u3057\u305f\u89e3\u96e2\u306b\u3064\u306a\u304c\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3055\u3089\u306b\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306e\u7d50\u5408\u306f\u3001\u03b114\u30d8\u30ea\u30c3\u30af\u30b9\u3092\u300c\u5916\u5411\u304d\u300d\u306e\u69cb\u9020\u3067\u5b89\u5b9a\u3055\u305b\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u300c\u5916\u5411\u304d\u300d\u306e\u72b6\u614b\u306f\u901a\u5e38\u3001\u9ad8\u3044\u89e6\u5a92\u6d3b\u6027\u3068\u7d50\u3073\u3064\u3044\u3066\u3044\u307e\u3059\u304c\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u304c\u90e8\u4f4d\u306b\u5165\u308a\u8fbc\u307f\u3001H\u30eb\u30fc\u30d7\u304c\u9589\u3058\u308b\u3053\u3068\u3067\u3001\u9175\u7d20\u306f\u89e6\u5a92\u3068\u3057\u3066\u50cd\u3051\u306a\u304f\u306a\u308a\u307e\u3059\u3002<\/p>\n<p>\u3053\u306e\u963b\u5bb3\u306e\u5f37\u3055\u306f\u3001\u8abf\u7bc0\u30c9\u30e1\u30a4\u30f3GAF-A\u306bcGMP\u304c\u30a2\u30ed\u30b9\u30c6\u30ea\u30c3\u30af\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u3055\u3089\u306b\u9ad8\u307e\u308a\u307e\u3059\u3002\u89e6\u5a92\u90e8\u4f4d\u306e\u963b\u5bb3\u85ac\u3078\u306e\u89aa\u548c\u6027\u304c\u4e0a\u304c\u308a\u3001\u6301\u7d9a\u7684\u306a\u751f\u7406\u4f5c\u7528\u304c\u751f\u307e\u308c\u307e\u3059\u3002<\/p>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u304c\u4f53\u306b\u4e0e\u3048\u308b\u5f71\u97ff<\/h2>\n<h3>\u826f\u3044\u5f71\u97ff<\/h3>\n<section dir=\"auto\">\n<ul>\n<li><strong>cGMP\u306e\u8abf\u7bc0<\/strong>: \u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3001\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u3067cGMP\u306e\u5206\u89e3\u3092\u62c5\u3046PDE5\u9175\u7d20\u306e\u89e6\u5a92\u90e8\u4f4d\u306b\u7d50\u5408\u3057\u307e\u3059\u3002<\/li>\n<li><strong>\u5e73\u6ed1\u7b4b\u306e\u5f1b\u7de9<\/strong>: cGMP\u306e\u5206\u89e3\u3092\u9632\u3050\u3053\u3068\u3067\u3053\u306e\u30b7\u30b0\u30ca\u30eb\u5206\u5b50\u304c\u84c4\u7a4d\u3057\u3001\u7d30\u80de\u5185\u30ab\u30eb\u30b7\u30a6\u30e0\u304c\u6e1b\u5c11\u3001\u30df\u30aa\u30b7\u30f3\u8efd\u9396\u30ad\u30ca\u30fc\u30bc\u304c\u4e0d\u6d3b\u6027\u5316\u3055\u308c\u3001\u8840\u7ba1\u5e73\u6ed1\u7b4b\u304c\u7de9\u307f\u307e\u3059\u3002<\/li>\n<li><strong>\u523a\u6fc0\u3078\u306e\u4f9d\u5b58<\/strong>: \u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306f\u3001\u53d6\u308a\u51fa\u3057\u305f\u30d2\u30c8\u306e\u7d44\u7e54\u306b\u76f4\u63a5\u5f1b\u7de9\u4f5c\u7528\u3092\u793a\u3057\u307e\u305b\u3093\u3002\u305d\u306e\u4f5c\u7528\u306f\u3001\u4e00\u9178\u5316\u7a92\u7d20\u306e\u653e\u51fa\u3092\u4fc3\u3059\u6027\u7684\u523a\u6fc0\u306b\u5b8c\u5168\u306b\u4f9d\u5b58\u3057\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<\/section>\n<h3>\u6ccc\u5c3f\u5668\u30fb\u751f\u6b96\u306b\u95a2\u3059\u308b\u4f5c\u7528<\/h3>\n<ul>\n<li>\u52c3\u8d77\u306e\u7dad\u6301\uff1a\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u9670\u830e\u6d77\u7dbf\u4f53\u3078\u306e\u8840\u6d41\u3092\u5897\u3084\u3057\u3001\u8840\u6db2\u3092\u9589\u3058\u8fbc\u3081\u308b\u9759\u8108\u9589\u585e\u6a5f\u69cb\u3092\u52a9\u3051\u3066\u52c3\u8d77\u3092\u4fdd\u3061\u307e\u3059\u3002<\/li>\n<li>\u6301\u7d9a\u52c3\u8d77\u75c7\uff1a\u307e\u308c\u3067\u3059\u304c\u91cd\u3044\u526f\u4f5c\u7528\u3068\u3057\u3066\u30014\u6642\u9593\u4ee5\u4e0a\u7d9a\u304f\u75db\u307f\u3092\u4f34\u3046\u52c3\u8d77\u304c\u3042\u308a\u307e\u3059\u3002\u7d44\u7e54\u306e\u6c38\u4e45\u7684\u306a\u640d\u50b7\u3092\u9632\u3050\u305f\u3081\u3001\u7dca\u6025\u306e\u533b\u7642\u51e6\u7f6e\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li>\u751f\u6b96\u80fd\u529b\u3068\u7cbe\u5b50\uff1a\u5065\u5eb7\u306a\u5fd7\u9858\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u5358\u56de\u6295\u4e0e\u306f\u7cbe\u5b50\u306e\u6570\u3001\u904b\u52d5\u7387\u3001\u5f62\u614b\u306b\u60aa\u5f71\u97ff\u3092\u4e0e\u3048\u306a\u3044\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>\u4e0d\u5fdc\u671f\uff1a\u5c04\u7cbe\u5f8c\u306e\u4e0d\u5fdc\u671f\u3092\u77ed\u304f\u3057\u3001\u6027\u884c\u70ba\u3092\u65e9\u304f\u518d\u958b\u3067\u304d\u308b\u3088\u3046\u306b\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u5fc3\u8840\u7ba1\u3078\u306e\u4f5c\u7528<\/h3>\n<ul>\n<li>\u5168\u8eab\u306e\u8840\u5727\uff1a\u5065\u5eb7\u306a\u4eba\u3067\u306f\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u901a\u5e38\u3001\u8840\u5727\u3092\u308f\u305a\u304b\u306b\u4e00\u6642\u7684\u306b\u4e0b\u3052\u307e\u3059\uff08\u53ce\u7e2e\u671f\u3067\u7d048.4mmHg\u3001\u62e1\u5f35\u671f\u3067\u7d045.5mmHg\u306e\u4f4e\u4e0b\uff09\u3002<\/li>\n<li>\u785d\u9178\u85ac\u3068\u306e\u76f8\u4e92\u4f5c\u7528\uff1a\u6700\u3082\u91cd\u8981\u306a\u5b89\u5168\u4e0a\u306e\u554f\u984c\u306f\u3001\u785d\u9178\u85ac\uff08\u30cb\u30c8\u30ed\u30b0\u30ea\u30bb\u30ea\u30f3\u306a\u3069\uff09\u3068\u306e\u4f75\u7528\u304c\u7d76\u5bfe\u7981\u5fcc\u3067\u3042\u308b\u3053\u3068\u3067\u3059\u3002\u4e21\u8005\u306f\u76f8\u4e57\u7684\u306b\u4f5c\u7528\u3057\u3066cGMP\u3092\u5236\u5fa1\u4e0d\u80fd\u306b\u84c4\u7a4d\u3055\u305b\u3001\u91cd\u5ea6\u3067\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u81f4\u547d\u7684\u306a\u4f4e\u8840\u5727\u3092\u62db\u304f\u304a\u305d\u308c\u304c\u3042\u308a\u307e\u3059\u3002<\/li>\n<li>\u91cd\u3044\u4e8b\u8c61\uff1a\u5e02\u8ca9\u5f8c\u306e\u5831\u544a\u3067\u306f\u3001\u5fc3\u7b4b\u6897\u585e\u3001\u4e0d\u6574\u8108\u3001\u8133\u5352\u4e2d\u3068\u3044\u3063\u305f\u307e\u308c\u306a\u4e8b\u8c61\u304c\u78ba\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u305d\u306e\u591a\u304f\u306f\u5fc3\u8840\u7ba1\u30ea\u30b9\u30af\u3092\u5143\u3005\u62b1\u3048\u3066\u3044\u305f\u60a3\u8005\u3055\u3093\u3067\u8d77\u304d\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u80ba\u3078\u306e\u4f5c\u7528<\/h3>\n<ul>\n<li>\u80ba\u8840\u7ba1\u306e\u62e1\u5f35\uff1a\u3053\u306e\u76ee\u7684\u3067\u306fRevatio\u3068\u3044\u3046\u540d\u79f0\u3067\u8ca9\u58f2\u3055\u308c\u3001\u30b7\u30eb\u30c7\u30ca\u30d5\u30a3\u30eb\u306fPDE5\u304c\u591a\u304f\u5b58\u5728\u3059\u308b\u80ba\u52d5\u8108\u5e8a\u306e\u8840\u7ba1\u3092\u7de9\u3081\u307e\u3059\u3002<\/li>\n<li>\u904b\u52d5\u80fd\u529b\u306e\u6539\u5584\uff1a\u80ba\u8840\u7ba1\u62b5\u6297\u3068\u5e73\u5747\u80ba\u52d5\u8108\u5727\u3092\u4e0b\u3052\u3001\u80ba\u52d5\u8108\u6027\u80ba\u9ad8\u8840\u5727\u75c7\u306e\u60a3\u8005\u3055\u3093\u306e\u904b\u52d5\u80fd\u529b\u3092\u9ad8\u3081\u3001\u81e8\u5e8a\u7684\u306a\u60aa\u5316\u3092\u9045\u3089\u305b\u307e\u3059\u3002<\/li>\n<li>\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\u306e\u6291\u5236\uff1a\u8fd1\u5e74\u306e\u7814\u7a76\u3067\u306f\u3001\u904e\u5270\u306b\u5897\u3048\u305f\u7b4b\u7d30\u80de\u306e\u7d30\u80de\u6b7b\u3092\u4fc3\u3059\u3053\u3068\u3067\u3001\u5c0f\u3055\u306a\u80ba\u52d5\u8108\u306e\u75c5\u7684\u306a\u30ea\u30e2\u30c7\u30ea\u30f3\u30b0\uff08\u80a5\u539a\uff09\u3092\u6291\u3048\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<\/ul>\n<h3>\u611f\u899a\u3068\u795e\u7d4c\u7cfb\u3078\u306e\u4f5c\u7528<\/h3>\n<ul>\n<li>\u8996\u899a\u306e\u7570\u5e38\uff1a\u60a3\u8005\u3055\u3093\u306e\u7d043\u301c11\uff05\u304c\u3001\u9752\u8996\u75c7\uff08\u8996\u754c\u304c\u9752\u307f\u304c\u304b\u308b\uff09\u3001\u304b\u3059\u307f\u76ee\u3001\u5149\u3078\u306e\u904e\u654f\u3068\u3044\u3063\u305f\u8996\u899a\u306e\u526f\u4f5c\u7528\u3092\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u5149\u306e\u53d7\u5bb9\u306b\u4e0d\u53ef\u6b20\u306a\u7db2\u819c\u306ePDE6\u304c\u90e8\u5206\u7684\u306b\u963b\u5bb3\u3055\u308c\u308b\u305f\u3081\u3067\u3059\u3002<\/li>\n<li>NAION\uff1a\u307e\u308c\u3067\u3059\u304c\u56de\u5fa9\u3057\u306a\u3044\u75be\u60a3\u3068\u3057\u3066\u3001\u7a81\u7136\u306e\u8996\u529b\u4f4e\u4e0b\u3092\u8d77\u3053\u3059\u975e\u52d5\u8108\u708e\u6027\u524d\u90e8\u865a\u8840\u6027\u8996\u795e\u7d4c\u75c7\uff08NAION\uff09\u304c\u3001\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u4f7f\u7528\u3068\u6642\u9593\u7684\u306b\u95a2\u9023\u3057\u3066\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/li>\n<li>\u8074\u529b\u4f4e\u4e0b\uff1a\u7a81\u767a\u6027\u306e\u611f\u97f3\u96e3\u8074\u304c\u307e\u308c\u306b\u5831\u544a\u3055\u308c\u3001\u8033\u9cf4\u308a\u3084\u3081\u307e\u3044\u3092\u4f34\u3046\u3053\u3068\u3082\u3042\u308a\u3001FDA\u306b\u3088\u308b\u6dfb\u4ed8\u6587\u66f8\u306e\u6539\u8a02\u304c\u7fa9\u52d9\u3065\u3051\u3089\u308c\u307e\u3057\u305f\u3002<\/li>\n<li>\u4e2d\u67a2\u795e\u7d4c\u306e\u4fdd\u8b77\uff1a\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001\u865a\u8840\u6027\u8133\u5352\u4e2d\u5f8c\u306e\u6897\u585e\u5de3\u306e\u7e2e\u5c0f\u3084\u8a8d\u77e5\u884c\u52d5\u306e\u6539\u5584\u306a\u3069\u3001\u795e\u7d4c\u4fdd\u8b77\u4f5c\u7528\u306e\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u30d2\u30c8\u3067\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<\/ul>\n<h3>\u3088\u304f\u3042\u308b\u4e00\u822c\u7684\u306a\u526f\u4f5c\u7528<\/h3>\n<section dir=\"auto\">\n<p>\u6700\u3082\u591a\u304f\u5831\u544a\u3055\u308c\u308b\u526f\u4f5c\u7528\u306f\u3001\u982d\u75db\u3001\u307b\u3066\u308a\u3001\u6d88\u5316\u4e0d\u826f\uff08\u80c3\u306e\u4e0d\u5feb\u611f\uff09\u3001\u9f3b\u3065\u307e\u308a\u3001\u8170\u75db\u3001\u7b4b\u8089\u75db\u3001\u5410\u304d\u6c17\u3001\u3081\u307e\u3044\u3067\u3059\u3002<\/p>\n<\/section>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u5b89\u5168\u306a\u98f2\u307f\u65b9<\/h2>\n<h3>\u63a8\u5968\u7528\u91cf<\/h3>\n<ul>\n<li>\u4e00\u822c\u7684\u306a\u958b\u59cb\u7528\u91cf\uff1a50mg<\/li>\n<li>\u53cd\u5fdc\u306b\u5fdc\u3058\u306625mg\u307e\u305f\u306f100mg\u306b\u8abf\u6574\u3067\u304d\u307e\u3059<\/li>\n<li>1\u65e51\u56de\u3001\u6027\u884c\u70ba\u306e\u304a\u3088\u305d30\u301c60\u5206\u524d\u306b\u670d\u7528\u3057\u307e\u3059<\/li>\n<\/ul>\n<p>\u5fc5\u305a\u533b\u5e2b\u306e\u6307\u793a\u306b\u5f93\u3063\u3066\u304f\u3060\u3055\u3044\u3002 <\/p>\n<h3>\u52b9\u679c\u3092\u9ad8\u3081\u308b\u30b3\u30c4<\/h3>\n<ul>\n<li>\u65e9\u304f\u52b9\u304b\u305b\u305f\u3044\u3068\u304d\u306f\u7a7a\u8179\u6642\u306b\u670d\u7528\u3059\u308b<\/li>\n<li>\u670d\u7528\u524d\u306e\u8102\u3063\u3053\u3044\u98df\u4e8b\u306f\u907f\u3051\u308b<\/li>\n<li>\u98f2\u9152\u3092\u63a7\u3048\u308b<\/li>\n<li>1\u65e5\u306b2\u56de\u4ee5\u4e0a\u670d\u7528\u3057\u306a\u3044<\/li>\n<\/ul>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u3092\u4f7f\u3048\u308b\u4eba\u30fb\u4f7f\u3048\u306a\u3044\u4eba<\/h2>\n<h3>\u9069\u3057\u3066\u3044\u308b\u4eba<\/h3>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u304c\u9069\u3057\u3066\u3044\u308b\u306e\u306f\uff1a<\/p>\n<ul>\n<li>\u52c3\u8d77\u4e0d\u5168\u3068\u8a3a\u65ad\u3055\u308c\u305f\u7537\u6027<\/li>\n<li>ED\u306e\u6cbb\u7642\u3092\u5e0c\u671b\u3059\u308b\u4eba<\/li>\n<\/ul>\n<h3>\u30d0\u30a4\u30a2\u30b0\u30e9\u3092\u907f\u3051\u308b\u3079\u304d\u4eba<\/h3>\n<p>\u6b21\u306b\u5f53\u3066\u306f\u307e\u308b\u5834\u5408\u306f\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<ul>\n<li>\u785d\u9178\u85ac\u3092\u670d\u7528\u3057\u3066\u3044\u308b\uff08\u5fc3\u81d3\u306e\u75c5\u6c17\u306e\u305f\u3081\uff09<\/li>\n<li>\u91cd\u3044\u5fc3\u81d3\u3084\u809d\u81d3\u306e\u75c5\u6c17\u304c\u3042\u308b<\/li>\n<li>\u8840\u5727\u304c\u4f4e\u3044<\/li>\n<li>\u6027\u884c\u70ba\u3092\u63a7\u3048\u308b\u3088\u3046\u6307\u5c0e\u3055\u308c\u3066\u3044\u308b<\/li>\n<\/ul>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u52b9\u679c\u306f\u3069\u306e\u304f\u3089\u3044\u7d9a\u304f\uff1f<\/h2>\n<p>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u52b9\u679c\u306f\u901a\u5e38<a href=\"https:\/\/indogenmed.org\/ja\/resource\/how-long-does-cenforce-100-last-timing-onset-effect\/\" target=\"_blank\" rel=\"noopener\">4\u301c6\u6642\u9593<\/a>\u7d9a\u304d\u307e\u3059\u304c\u3001\u6b21\u306e\u8981\u56e0\u306b\u3088\u3063\u3066\u5909\u308f\u308a\u307e\u3059\u3002<\/p>\n<ul>\n<li>\u5e74\u9f62<\/li>\n<li>\u4ee3\u8b1d<\/li>\n<li>\u98df\u4e8b<\/li>\n<li>\u5168\u8eab\u306e\u5065\u5eb7\u72b6\u614b<\/li>\n<\/ul>\n<p>\u3053\u308c\u306f\u305d\u306e\u9593\u305a\u3063\u3068\u52c3\u8d77\u304c\u7d9a\u304f\u3068\u3044\u3046\u610f\u5473\u3067\u306f\u306a\u304f\u3001\u305d\u306e\u6642\u9593\u5e2f\u306b\u52c3\u8d77\u3057\u3084\u3059\u304f\u306a\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n<h2>\u30d0\u30a4\u30a2\u30b0\u30e9\u306e\u8aa4\u89e3\u3068\u4e8b\u5b9f<\/h2>\n<ul>\n<li>\u8aa4\u89e3\uff1a\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u3059\u3050\u52b9\u304f<br \/>\u4e8b\u5b9f\uff1a\u52b9\u304d\u59cb\u3081\u308b\u307e\u3067\u7d0430\u301c60\u5206\u304b\u304b\u308a\u307e\u3059<\/li>\n<li>\u8aa4\u89e3\uff1a\u30d0\u30a4\u30a2\u30b0\u30e9\u3067\u81ea\u52d5\u7684\u306b\u52c3\u8d77\u3059\u308b<br \/>\u4e8b\u5b9f\uff1a\u6027\u7684\u523a\u6fc0\u304c\u5fc5\u8981\u3067\u3059<\/li>\n<li>\u8aa4\u89e3\uff1a\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u9ad8\u9f62\u306e\u7537\u6027\u306e\u305f\u3081\u306e\u85ac<br \/>\u4e8b\u5b9f\uff1aED\u304c\u3042\u308c\u3070\u5e74\u9f62\u3092\u554f\u308f\u305a\u4f7f\u7528\u3067\u304d\u307e\u3059<\/li>\n<\/ul>\n<h2>\u307e\u3068\u3081<\/h2>\n<p><em>\u300c\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4f55\u3092\u3059\u308b\u85ac\u304b\u300d<\/em>\u3068\u3044\u3046\u554f\u3044\u306b\u7b54\u3048\u308b\u306a\u3089\u3001\u9670\u830e\u3078\u306e\u8840\u6d41\u3092\u6539\u5584\u3057\u3001\u6027\u884c\u70ba\u4e2d\u306b\u52c3\u8d77\u3092\u5f97\u3066\u7dad\u6301\u3057\u3084\u3059\u304f\u3059\u308b\u85ac\u3060\u3068\u3044\u3048\u307e\u3059\u3002<\/p>\n<p>\u6b63\u3057\u304f\u4f7f\u3048\u3070\u3001\u52c3\u8d77\u4e0d\u5168\u306b\u5bfe\u3057\u3066\u5b89\u5168\u3067\u52b9\u679c\u7684\u306a\u6cbb\u7642\u3067\u3059\u3002\u305f\u3060\u3057\u3001\u5b89\u5168\u306b\u4f7f\u3044\u526f\u4f5c\u7528\u3092\u907f\u3051\u308b\u305f\u3081\u306b\u306f\u3001\u533b\u5e2b\u306e\u6307\u5c0e\u304c\u6b20\u304b\u305b\u307e\u305b\u3093\u3002<\/p>\n<h2>\u53c2\u8003\u6587\u732e<\/h2>\n<ul>\n<li>Medical News Today \u2013 <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/viagra\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.medicalnewstoday.com\/articles\/viagra<\/a><\/li>\n<li>NHS \u2013 <a href=\"https:\/\/www.nhs.uk\/medicines\/sildenafil-viagra\/about-sildenafil-viagra\/\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.nhs.uk\/medicines\/sildenafil-viagra\/about-sildenafil-viagra\/<\/a><\/li>\n<li>GoodRx \u2013 <a href=\"https:\/\/www.goodrx.com\/viagra\/what-is\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.goodrx.com\/viagra\/what-is<\/a><\/li>\n<li>\u30d5\u30a1\u30a4\u30b6\u30fc\u6dfb\u4ed8\u6587\u66f8 \u2013 <a href=\"https:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=652&amp;section=ppi\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/labeling.pfizer.com\/ShowLabeling.aspx?id=652&amp;section=ppi<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u533b\u7642\u76e3\u4fee\uff1a \u672c\u8a18\u4e8b\u306f2026\u5e744\u67083\u65e5\u306b\u5f53\u793e\u306e\u81e8\u5e8a\u30b5\u30dd\u30fc\u30c8\u30c1\u30fc\u30e0\u304c\u78ba\u8a8d\u3057\u307e\u3057\u305f\u3002 \u300c\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u4f55\u3092\u3059\u308b\u85ac\u306a\u306e\u304b\u300d\u3068\u7591\u554f\u306b\u601d\u3063\u305f\u3053\u3068\u304c\u3042\u308b\u65b9\u306f\u591a\u3044\u3067\u3057\u3087\u3046\u3002\u30d0\u30a4\u30a2\u30b0\u30e9\u306f\u52c3\u8d77\u4e0d\u5168\uff08ED\uff09\u306e\u6cbb\u7642\u85ac\u3068\u3057\u3066\u6700\u3082\u3088\u304f\u77e5\u3089\u308c\u305f\u85ac\u306e\u4e00 [&hellip;]<\/p>\n","protected":false},"author":2145,"featured_media":137055,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5945,5955,5949],"tags":[],"class_list":["post-132394","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-erectile-dysfunction","category-generic-drugs","category-sildenafil-viagra-guide"],"_links":{"self":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/posts\/132394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/users\/2145"}],"replies":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/comments?post=132394"}],"version-history":[{"count":0,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/posts\/132394\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/media\/137055"}],"wp:attachment":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/media?parent=132394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/categories?post=132394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/tags?post=132394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}