{"id":138952,"date":"2026-05-02T10:29:54","date_gmt":"2026-05-02T10:29:54","guid":{"rendered":"https:\/\/indogenmed.org\/product\/xinep-5-ml-tablets\/"},"modified":"2026-08-27T19:30:55","modified_gmt":"2026-08-27T19:30:55","slug":"xinep-5-ml-tablets","status":"publish","type":"product","link":"https:\/\/indogenmed.org\/ja\/product\/xinep-5-ml-tablets\/","title":{"rendered":"Xinep 5 Ml"},"content":{"rendered":"<p><!-- Xinep 5 ml Eye Drops: Comprehensive Clinical Guide --><\/p>\n<p><strong>Xinep 5 ml Eye Drops<\/strong> (Nepafenac Ophthalmic Suspension 0.1% w\/v) is a specialized non-steroidal anti-inflammatory drug (NSAID) manufactured by <strong>Sunways (India) Pvt Ltd<\/strong>. engineered specifically for the management of pain and inflammation associated with cataract surgery. As a prodrug with unique lipophilic properties, Xinep offers superior ocular tissue penetration, making it an essential component of modern perioperative ophthalmic protocols.<\/p>\n<h2>1. Manufacturer Profile: Sunways (India) Pvt Ltd<\/h2>\n<p>Sunways India is a premier pharmaceutical organization specializing in ophthalmic and ENT care, known for its focus on advanced delivery mechanisms and patient-centric research.<\/p>\n<ul>\n<li><strong>Manufacturing Standards:<\/strong> Produced in WHO-GMP certified facilities, ensuring that each 5 ml suspension maintains precise particle distribution for consistent dosing.<\/li>\n<li><strong>Innovation:<\/strong> Sunways utilizes high-purity Nepafenac to ensure that Xinep matches the clinical efficacy of innovator brands while remaining accessible to a global patient base.<\/li>\n<\/ul>\n<h2>2. Composition &#038; Ingredients<\/h2>\n<p>Each 1 ml of Xinep Eye Drops contains:<\/p>\n<ul>\n<li><strong>Active Ingredient:<\/strong> Nepafenac 1 mg (0.1% w\/v).<\/li>\n<li><strong>Preservative:<\/strong> Benzalkonium Chloride 0.005% w\/v.<\/li>\n<li><strong>Vehicle:<\/strong> Sterile aqueous suspension with specialized stabilizers for enhanced corneal contact time.<\/li>\n<\/ul>\n<h2>3. Mechanism of Action: How It Works<\/h2>\n<p>Xinep operates as a targeted anti-inflammatory agent through a unique &#8220;prodrug&#8221; activation process.<\/p>\n<h3>A. Targeted Prodrug Activation<\/h3>\n<p>Upon instillation, Nepafenac penetrates the cornea. Intraocular hydrolases then convert the prodrug into its active form, <strong>Amfenac<\/strong>. This localized conversion ensures that the highest concentration of the active drug is delivered directly to the iris, ciliary body, and retina, minimizing systemic side effects.<\/p>\n<h3>B. COX-1 and COX-2 Inhibition<\/h3>\n<p>Amfenac is a potent inhibitor of the cyclooxygenase (COX-1 and COX-2) enzymes. By blocking these enzymes, Xinep halts the synthesis of <strong>prostaglandins<\/strong>\u2014the primary chemical mediators of pain, swelling, and inflammation in the eye. This prevents post-operative complications like cystoid macular edema (CME).<\/p>\n<h2>4. Therapeutic Indications<\/h2>\n<p>Xinep 5 ml is clinically indicated for:<\/p>\n<ul>\n<li><strong>Post-Operative Inflammation:<\/strong> Reducing redness and swelling following cataract extraction.<\/li>\n<li><strong>Cataract Surgery Pain:<\/strong> Preventing and treating ocular pain during the recovery period.<\/li>\n<li><strong>Cystoid Macular Edema (CME):<\/strong> Often prescribed as a preventative measure in high-risk diabetic patients undergoing eye surgery.<\/li>\n<\/ul>\n<h2>5. Clinical Comparison: Xinep vs. Patanol<\/h2>\n<table border=\"1\">\n<thead>\n<tr>\n<th>Feature<\/th>\n<th>Xinep (Nepafenac)<\/th>\n<th>Patanol (Olopatadine)<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Drug Class<\/td>\n<td>NSAID (Anti-inflammatory)<\/td>\n<td>Antihistamine (Anti-allergy)<\/td>\n<\/tr>\n<tr>\n<td>Primary Target<\/td>\n<td>**Post-Surgical Pain**<\/td>\n<td>Allergic Itching\/Redness<\/td>\n<\/tr>\n<tr>\n<td>Mechanism<\/td>\n<td>Prostaglandin Inhibition<\/td>\n<td>Histamine H1 Antagonism<\/td>\n<\/tr>\n<tr>\n<td>Best For<\/td>\n<td>Cataract Recovery<\/td>\n<td>Seasonal Allergy<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>6. Dosing &#038; Administration<\/h2>\n<h3>Perioperative Surgical Regimen<\/h3>\n<ul>\n<li><strong>Pre-Surgery:<\/strong> Instill 1 drop three times daily, starting 1 day before surgery.<\/li>\n<li><strong>Day of Surgery:<\/strong> 1 drop on the morning of the procedure.<\/li>\n<li><strong>Post-Surgery:<\/strong> 1 drop three times daily for up to 2 weeks, or as directed by your surgeon.<\/li>\n<\/ul>\n<h3>Application Guidelines<\/h3>\n<ol>\n<li>Wash hands and shake the bottle well (suspension must be mixed).<\/li>\n<li>Tilt the head back and pull down the lower lid.<\/li>\n<li>Instill one drop without touching the dropper tip to the eye.<\/li>\n<li>\u76ee\u3092\u9589\u3058\u3001\u5185\u5074\u306e\u9685\u306b60\u79d2\u9593\u8efd\u304f\u5727\u3092\u52a0\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li>\u4ed6\u306e\u70b9\u773c\u85ac\u3092\u4f7f\u7528\u3059\u308b\u5834\u5408\u306f\u3001\u5c11\u306a\u304f\u3068\u30825\u5206\u9593\u306e\u9593\u9694\u3092\u7a7a\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ol>\n<h2>7. \u6ce8\u610f\u4e8b\u9805\u3068\u5b89\u5168\u4e0a\u306e\u8b66\u544a<\/h2>\n<ul>\n<li><strong>\u51fa\u8840\u50be\u5411:<\/strong> \u65e2\u77e5\u306e\u51fa\u8840\u50be\u5411\u304c\u3042\u308b\u60a3\u8005\u3084\u8840\u6db2\u51dd\u56fa\u963b\u5bb3\u85ac\u3092\u4f7f\u7528\u4e2d\u306e\u60a3\u8005\u306f\u614e\u91cd\u306b\u4f7f\u7528\u3057\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<li><strong>\u89d2\u819c\u3078\u306e\u5f71\u97ff:<\/strong> \u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6d88\u708e\u5264\u306e\u9577\u671f\u4f7f\u7528\u306f\u3001\u89d2\u819c\u708e\u3084\u89d2\u819c\u306e\u8584\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9577\u671f\u4f7f\u7528\u306e\u5834\u5408\u306f\u5c02\u9580\u533b\u306b\u3088\u308b\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u5fc5\u8981\u3067\u3059\u3002<\/li>\n<li><strong>\u30b3\u30f3\u30bf\u30af\u30c8\u30ec\u30f3\u30ba:<\/strong> \u624b\u8853\u5f8c\u671f\u9593\u4e2d\u306fXinep\u3092\u4f7f\u7528\u4e2d\u306f\u30b3\u30f3\u30bf\u30af\u30c8\u30ec\u30f3\u30ba\u306e\u88c5\u7740\u3092\u907f\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/li>\n<\/ul>\n<h2>8. \u5fb9\u5e95\u7684\u306b\u8abf\u67fb\u3055\u308c\u305fFAQ<\/h2>\n<h3>Q: Xinep\u306f\u30b9\u30c6\u30ed\u30a4\u30c9\u70b9\u773c\u85ac\u3067\u3059\u304b\uff1f<\/h3>\n<p><strong>A:<\/strong> \u3044\u3044\u3048\u3002Xinep\u306f\u975e\u30b9\u30c6\u30ed\u30a4\u30c9\u6027\u6297\u708e\u75c7\u85ac\uff08NSAID\uff09\u3067\u3059\u3002\u30b9\u30c6\u30ed\u30a4\u30c9\u306b\u4f34\u3046\u773c\u5727\u4e0a\u6607\u306a\u3069\u306e\u526f\u4f5c\u7528\u3092\u4f34\u308f\u305a\u3001\u5f37\u529b\u306a\u6297\u708e\u75c7\u4f5c\u7528\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002<\/p>\n<h3>Q: \u306a\u305c\u30dc\u30c8\u30eb\u3092\u632f\u308b\u5fc5\u8981\u304c\u3042\u308b\u306e\u3067\u3059\u304b\uff1f<\/h3>\n<p><strong>A:<\/strong> Xinep\u306f\u61f8\u6fc1\u6db2\u3067\u3042\u308b\u305f\u3081\u3001\u85ac\u5264\u304c\u5e95\u90e8\u306b\u6c88\u6bbf\u3057\u307e\u3059\u3002\u632f\u308b\u3053\u3068\u3067\u3001\u6bce\u56de\u6b63\u78ba\u306a\u6295\u4e0e\u91cf\u3092\u5f97\u3089\u308c\u308b\u3088\u3046\u306b\u3057\u307e\u3059\u3002<\/p>\n<h3>Q: \u30a2\u30ec\u30eb\u30ae\u30fc\u306b\u3088\u308b\u8d64\u307f\u306bXinep\u3092\u4f7f\u7528\u3067\u304d\u307e\u3059\u304b\uff1f<\/h3>\n<p><strong>A:<\/strong> Xinep\u306f\u708e\u75c7\u3092\u6291\u3048\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u304c\u3001\u6297\u30d2\u30b9\u30bf\u30df\u30f3\u5264\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30a2\u30ec\u30eb\u30ae\u30fc\u6027\u306e\u8d64\u307f\u306b\u306f\u3001\u901a\u5e38\u30aa\u30ed\u30d1\u30bf\u30b8\u30f3\u306a\u3069\u306e\u88fd\u54c1\u306e\u65b9\u304c\u52b9\u679c\u7684\u3067\u3059\u3002<\/p>\n<h2>9. \u516c\u5f0f\u898f\u5236\u53c2\u7167<\/h2>\n<ol>\n<li><strong>Sunways Ophthalmic Index:<\/strong> <a href=\"https:\/\/www.sunways.com\" rel=\"nofollow noopener\" target=\"_blank\">\u516c\u5f0f\u88fd\u54c1\u4e00\u89a7<\/a><\/li>\n<li><strong>FDA Monographs:<\/strong> Nepafenac 0.1%\u306e\u81e8\u5e8a\u85ac\u7406\u5b66\u3002<\/li>\n<\/ol>\n<hr \/>\n<p><em><strong>\u533b\u7642\u4e0a\u306e\u514d\u8cac\u4e8b\u9805:<\/strong> \u672c\u30b3\u30f3\u30c6\u30f3\u30c4\u306f\u6559\u80b2\u76ee\u7684\u3067AI\u304c\u751f\u6210\u3057\u305f\u3082\u306e\u3067\u3042\u308a\u3001\u533b\u7642\u30a2\u30c9\u30d0\u30a4\u30b9\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u8a3a\u65ad\u3084\u6cbb\u7642\u306b\u3064\u3044\u3066\u306f\u5fc5\u305a\u533b\u5e2b\u3084\u533b\u7642\u5c02\u9580\u5bb6\u306b\u3054\u76f8\u8ac7\u304f\u3060\u3055\u3044\u3002<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Xinep 5 ml Eye Drops (Nepafenac Ophthalmic Suspension 0.1% w\/v) is a specialized non-steroidal anti-inflammato [&hellip;]<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":[],"product_brand":[12029],"product_cat":[16265],"product_tag":[11761,11800],"igm_manufacturer":[],"class_list":["post-138952","product","type-product","status-publish","product_brand-ajanta-pharma-limited","product_cat-mens-health-wellness","product_tag-eye-drops","product_tag-vial-bottle","pa_brand-name-xinep","pa_molecule-xinep","first","instock","sale","shipping-taxable","purchasable","product-type-simple"],"_links":{"self":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/product\/138952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/comments?post=138952"}],"wp:attachment":[{"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/media?parent=138952"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/product_brand?post=138952"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/product_cat?post=138952"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/product_tag?post=138952"},{"taxonomy":"igm_manufacturer","embeddable":true,"href":"https:\/\/indogenmed.org\/ja\/wp-json\/wp\/v2\/igm_manufacturer?post=138952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}