{"id":138905,"date":"2026-05-02T10:29:49","date_gmt":"2026-05-02T10:29:49","guid":{"rendered":"https:\/\/indogenmed.org\/product\/tobrasone-5-ml-tablets\/"},"modified":"2026-08-27T20:00:43","modified_gmt":"2026-08-27T20:00:43","slug":"tobrasone-5-ml-tablets","status":"publish","type":"product","link":"https:\/\/indogenmed.org\/ru\/product\/tobrasone-5-ml-tablets\/","title":{"rendered":"Tobrasone 5 Ml"},"content":{"rendered":"

<\/p>\n

Tobrasone 5 ml Eye Drops<\/strong> (Tobramycin 0.3% & Fluorometholone 0.1% Ophthalmic Suspension) is a high-performance, dual-action therapeutic formulation manufactured by Alcon<\/strong> (a Novartis division). Specifically engineered for the treatment of steroid-responsive inflammatory ocular conditions where a bacterial infection is present or suspected, Tobrasone combines a broad-spectrum aminoglycoside antibiotic with a moderate-potency corticosteroid. This combination is particularly valued in clinical practice for its ability to provide intensive anti-inflammatory relief with a significantly lower risk of elevating intraocular pressure (IOP) compared to more potent steroid combinations.<\/p>\n

1. Manufacturer Profile: Alcon (Novartis)<\/h2>\n

Alcon is a global leader in eye care innovation, recognized for its commitment to high-purity pharmaceutical formulations and advanced delivery systems.<\/p>\n

    \n
  • Quality Assurance:<\/strong> Produced in world-class facilities certified under WHO-GMP and US FDA standards, ensuring that every 5 ml unit of Tobrasone maintains precise molecular stability and sterility.<\/li>\n
  • Innovation:<\/strong> Alcon\u2019s expertise in suspension technology ensures that the active ingredients in Tobrasone are uniformly distributed, providing a consistent therapeutic dose with every actuation.<\/li>\n<\/ul>\n

    2. Composition & Active Ingredients<\/h2>\n

    Each 1 ml of Tobrasone contains a synergistic ratio of active agents:<\/p>\n

      \n
    • Tobramycin USP:<\/strong> 3 mg (0.3% w\/v) \u2013 Bactericidal antibiotic.<\/li>\n
    • Fluorometholone USP:<\/strong> 1 mg (0.1% w\/v) \u2013 Moderate-potency corticosteroid.<\/li>\n
    • Preservative:<\/strong> Benzalkonium Chloride 0.01% w\/v (standard multi-dose stabilizer).<\/li>\n
    • Vehicle:<\/strong> Sterile aqueous suspension designed for optimal corneal adherence.<\/li>\n<\/ul>\n

      3. Mechanism of Action: How It Works<\/h2>\n

      Tobrasone utilizes a two-pronged attack to eliminate bacterial pathogens and suppress the body’s inflammatory response.<\/p>\n

      A. Rapid Antibacterial Coverage (Tobramycin)<\/h3>\n

      Tobramycin works by irreversibly binding to the 30S and 50S subunits<\/strong> of the bacterial ribosome. This action effectively halts the synthesis of essential proteins required for bacterial growth and replication. It is highly active against common ocular pathogens, including Staphylococcus aureus<\/em> and Pseudomonas aeruginosa<\/em>.<\/p>\n

      B. Safe Anti-Inflammatory Control (Fluorometholone)<\/h3>\n

      Fluorometholone is a «soft» steroid that inhibits the release of prostaglandins and other chemical mediators of inflammation. Its unique molecular structure allows it to be rapidly metabolized within the eye, which provides effective relief from redness and swelling while minimizing the risk of «steroid-induced» increases in eye pressure\u2014a common complication with other corticosteroids like Dexamethasone.<\/p>\n

      4. Therapeutic Indications<\/h2>\n

      Tobrasone 5 ml is clinically indicated for:<\/p>\n

        \n
      • Inflammatory Bacterial Conjunctivitis:<\/strong> Treating infections accompanied by significant ocular swelling and irritation.<\/li>\n
      • Post-Operative Management:<\/strong> Reducing inflammation and preventing infection after cataract, glaucoma, or refractive surgeries.<\/li>\n
      • Steroid-Responsive Ocular Surface Disease:<\/strong> Managing severe blepharitis and keratitis where bacterial involvement is suspected.<\/li>\n
      • Ocular Trauma:<\/strong> \u041f\u0440\u0435\u0434\u043e\u0442\u0432\u0440\u0430\u0449\u0435\u043d\u0438\u0435 \u0432\u0442\u043e\u0440\u0438\u0447\u043d\u043e\u0439 \u0438\u043d\u0444\u0435\u043a\u0446\u0438\u0438 \u043f\u043e\u0441\u043b\u0435 \u043d\u0435\u0431\u043e\u043b\u044c\u0448\u0438\u0445 \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0439 \u0440\u043e\u0433\u043e\u0432\u0438\u0446\u044b \u0438\u043b\u0438 \u0445\u0438\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0445 \u043e\u0436\u043e\u0433\u043e\u0432.<\/li>\n<\/ul>\n

        5. \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435: Tobrasone vs. TobraDex<\/h2>\n\n\n\n\n\n\n\n\n
        \u0425\u0430\u0440\u0430\u043a\u0442\u0435\u0440\u0438\u0441\u0442\u0438\u043a\u0430<\/th>\nTobrasone (Alcon)<\/th>\nTobraDex (Innovator)<\/th>\n<\/tr>\n<\/thead>\n
        \u0410\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a<\/td>\nTobramycin 0.3%<\/td>\nTobramycin 0.3%<\/td>\n<\/tr>\n
        \u0422\u0438\u043f \u0441\u0442\u0435\u0440\u043e\u0438\u0434\u0430<\/td>\n**Fluorometholone (Moderate)**<\/td>\nDexamethasone (Potent)<\/td>\n<\/tr>\n
        \u0420\u0438\u0441\u043a \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u0438\u044f \u0432\u043d\u0443\u0442\u0440\u0438\u0433\u043b\u0430\u0437\u043d\u043e\u0433\u043e \u0434\u0430\u0432\u043b\u0435\u043d\u0438\u044f<\/td>\n**\u0417\u043d\u0430\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u043d\u0438\u0436\u0435**<\/td>\n\u0412\u044b\u0448\u0435<\/td>\n<\/tr>\n
        \u041f\u0440\u043e\u0444\u0438\u043b\u044c \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u0430<\/td>\n\u041e\u0442\u043a\u043b\u0438\u043a \u043d\u0430 \u0441\u0442\u0435\u0440\u043e\u0438\u0434\u044b \/ \u0414\u0435\u0442\u0438<\/td>\n\u041e\u0441\u0442\u0440\u0430\u044f\/\u0421\u0438\u043b\u044c\u043d\u0430\u044f \u0438\u043d\u0444\u043b\u044f\u043c\u043c\u0430\u0446\u0438\u044f<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

        6. \u0414\u043e\u0437\u0438\u0440\u043e\u0432\u043a\u0430 \u0438 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435<\/h2>\n

        \u0421\u0442\u0430\u043d\u0434\u0430\u0440\u0442\u043d\u044b\u0439 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b \u0434\u043e\u0437\u0438\u0440\u043e\u0432\u043a\u0438<\/h3>\n