{"id":134500,"date":"2026-07-02T09:33:36","date_gmt":"2026-07-02T09:33:36","guid":{"rendered":"https:\/\/indogenmed.org\/resource\/tagrisso-top-trial-chemo-combination\/"},"modified":"2026-09-20T02:43:51","modified_gmt":"2026-09-20T02:43:51","slug":"tagrisso-top-trial-chemo-combination","status":"publish","type":"post","link":"https:\/\/indogenmed.org\/zh-hans\/resource\/tagrisso-top-trial-chemo-combination\/","title":{"rendered":"\u6cf0\u745e\u6c99\uff08\u5965\u5e0c\u66ff\u5c3c\uff09TOP\u8bd5\u9a8c\u7ed3\u679c\uff1a\u4e3a\u4f55\u8054\u5408\u5316\u7597\u66f4\u4f18"},"content":{"rendered":"<p>\u665a\u671f<a href=\"https:\/\/indogenmed.org\/medicine\/lung-cancer\/\" target=\"_blank\" rel=\"noopener\">\u80ba\u764c<\/a>\u7684\u6cbb\u7597\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\u3002\u591a\u5e74\u6765\uff0c\u60a3\u8005\u53ea\u80fd\u4f9d\u9760\u4f20\u7edf\u5316\u7597\uff0c\u5b83\u867d\u80fd\u6e05\u9664\u764c\u7ec6\u80de\uff0c\u5374\u4f1a\u7ed9\u5168\u8eab\u5e26\u6765\u8bf8\u591a\u526f\u4f5c\u7528\u3002<\/p>\n<p>\u7cbe\u51c6\u533b\u5b66\u7684\u7a81\u7834\u4f7f\u60c5\u51b5\u53d1\u751f\u4e86\u5de8\u5927\u53d8\u5316\u3002\u4eba\u4eec\u53d1\u73b0\uff0c\u80ba\u764c\u7684\u53d1\u751f\u4e0e\u8bb8\u591a\u57fa\u56e0\u7a81\u53d8\u6709\u5173\uff0c\u60a3\u8005\u9700\u8981\u7684\u662f\u53e3\u670d\u9776\u5411\u6cbb\u7597\uff0c\u800c\u4e0d\u662f\u5343\u7bc7\u4e00\u5f8b\u7684\u7597\u6cd5\u3002<\/p>\n<p>\u963f\u65af\u5229\u5eb7\u7684\u6cf0\u745e\u6c99\uff08\u901a\u7528\u540d\uff1a<a href=\"https:\/\/indogenmed.org\/zh-hans\/molecule\/osimertinib\/\" target=\"_blank\" rel=\"noopener\">\u5965\u5e0c\u66ff\u5c3c<\/a>\uff09\u6210\u4e3a\u8fd9\u573a\u53d8\u9769\u7684\u5173\u952e\u3002\u8fd9\u79cd\u7b2c\u4e09\u4ee3\u836f\u7269\u6210\u4e3a\u6240\u6709EGFR\u7a81\u53d8\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7684\u65b0\u6807\u51c6\u7597\u6cd5\u3002<\/p>\n<p>\u4f46\u533b\u5b66\u7684\u8fdb\u6b65\u6c38\u65e0\u6b62\u5883\u3002\u5c3d\u7ba1\u6cf0\u745e\u6c99\u5355\u836f\u5df2\u7ecf\u5e2e\u52a9\u4e86\u6210\u5343\u4e0a\u4e07\u7684\u4eba\uff0c\u764c\u7ec6\u80de\u6700\u7ec8\u8fd8\u662f\u4f1a\u627e\u5230\u7ed5\u8fc7\u8fd9\u79cd\u6cbb\u7597\u7684\u65b9\u6cd5\u3002<\/p>\n<p> \u4e3a\u4e86\u5bf9\u6297\u8fd9\u79cd\u8010\u836f\u6027\uff0c\u79d1\u5b66\u5bb6\u5f00\u59cb\u63a2\u7d22\u4e00\u79cd\u9769\u547d\u6027\u7684\u6cbb\u7597\u601d\u8def\uff1a\u5982\u679c\u4ece\u6cbb\u7597\u4e00\u5f00\u59cb\u5c31\u5c06<a href=\"https:\/\/indogenmed.org\/product\/tagrisso-80mg-tablets\/\" target=\"_blank\" rel=\"noopener\">\u6cf0\u745e\u6c99<\/a>\u9776\u5411\u6cbb\u7597\u4e0e\u5316\u7597\u8054\u5408\u4f7f\u7528\uff0c\u4f1a\u600e\u6837\uff1f<\/p>\n<p>\u4e24\u9879\u91cc\u7a0b\u7891\u5f0f\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014III\u671fFLAURA2\u8bd5\u9a8c\u548cIII\u671fTOP\u8bd5\u9a8c\u2014\u2014\u7684\u6700\u65b0\u7ed3\u679c\u8bc1\u5b9e\u4e86\u8fd9\u4e00\u7597\u6cd5\u7684\u6709\u6548\u6027\u3002\u672c\u6307\u5357\u5c06\u5bf9\u6b64\u8fdb\u884c\u8be6\u7ec6\u4ecb\u7ecd\u3002<\/p>\n<h2>\u79d1\u5b66\u4f9d\u636e\uff1a\u4e3a\u4f55\u5c06\u9776\u5411\u836f\u4e0e\u5316\u7597\u8054\u5408\uff1f<\/h2>\n<p>\u8981\u7406\u89e3\u8fd9\u79cd\u8054\u5408\u4e3a\u4f55\u5982\u6b64\u6709\u6548\uff0c\u9996\u5148\u8981\u4e86\u89e3\u764c\u7ec6\u80de\u5728\u4f53\u5185\u7684\u884c\u4e3a\u65b9\u5f0f\u3002<\/p>\n<h3>\u5355\u836f\u6cbb\u7597\u7684\u4f18\u52bf\u4e0e\u5c40\u9650<\/h3>\n<p>\u5355\u72ec\u4f7f\u7528\u65f6\uff0c\u8be5\u836f\u4f5c\u4e3aEGFR\u916a\u6c28\u9178\u6fc0\u9176\u6291\u5236\u5242\uff08TKI\uff09\u53d1\u6325\u4f5c\u7528\u3002<\/p>\n<p>\u5b83\u963b\u65ad\u764c\u7ec6\u80de\u4e0a\u7a81\u53d8\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff0c\u5207\u65ad\u6307\u4ee4\u80bf\u7624\u5206\u88c2\u7684\u5185\u90e8\u4fe1\u53f7\u3002<\/p>\n<p>\u8fd9\u79cd\u6cbb\u7597\u5bf9\u8bb8\u591a\u4eba\u6548\u679c\u663e\u8457\uff0c\u80bf\u7624\u8fc5\u901f\u7f29\u5c0f\uff0c\u75c7\u72b6\u5f97\u5230\u6539\u5584\u3002<\/p>\n<p>\u7136\u800c\uff0c\u80bf\u7624\u901a\u5e38\u4e0d\u662f\u5747\u4e00\u7684\u56e2\u5757\uff0c\u800c\u662f\u7531\u4e0d\u540c\u514b\u9686\u7ec6\u80de\u7fa4\u7ec4\u6210\u7684\u5f02\u8d28\u96c6\u5408\u3002<\/p>\n<p>\u968f\u7740\u65f6\u95f4\u63a8\u79fb\uff0c\u5373\u4f7f\u836f\u7269\u5df2\u6740\u6b7b\u4e86\u5e26\u6709EGFR\u7a81\u53d8\u7684\u4e3b\u8981\u764c\u7ec6\u80de\uff0c\u90e8\u5206\u764c\u7ec6\u80de\u4ecd\u4f1a\u53d1\u5c55\u51fa\u5176\u4ed6\u751f\u5b58\u548c\u751f\u957f\u9014\u5f84\u3002<\/p>\n<p>\u8fd9\u4e9b\u7ec6\u80de\u4e0d\u65ad\u589e\u6b96\u5e76\u5bf9\u836f\u7269\u4ea7\u751f\u8010\u836f\uff0c\u4f7f\u836f\u7269\u5931\u6548\u3002<\/p>\n<h3>\u53cc\u91cd\u6253\u51fb\u6548\u5e94<br 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aria-level=\"1\">\u5e7f\u8c31\u653b\u51fb\uff1a\u5316\u7597\u4e3b\u52a8\u6467\u6bc1\u5feb\u901f\u5206\u88c2\u7684\u7ec6\u80de\uff0c\u5728\u9690\u85cf\u7684\u3001\u4fb5\u88ad\u6027\u7684\u6216\u7a81\u53d8\u7684\u7ec6\u80de\u514b\u9686\u9002\u5e94\u5e76\u5bf9TKI\u4ea7\u751f\u8010\u836f\u4e4b\u524d\u5c06\u5176\u6e05\u9664\u3002<\/li>\n<\/ol>\n<p>\u8fd9\u79cd\u5f3a\u6548\u7ec4\u5408\u963b\u6b62\u80bf\u7624\u5efa\u7acb\u660e\u786e\u7684\u8010\u836f\u9014\u5f84\uff0c\u6bd4\u5355\u72ec\u670d\u836f\u80fd\u66f4\u957f\u65f6\u95f4\u5730\u5ef6\u7f13\u764c\u75c7\u8fdb\u5c55\u3002<\/p>\n<h2>\u91cc\u7a0b\u7891\u6570\u636e\uff1aFLAURA2\u6811\u7acb\u751f\u5b58\u65b0\u6807\u6746<br 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\/>\n<\/h3>\n<p>TOP\u8bd5\u9a8c\u7814\u7a76\u4e86\u6cf0\u745e\u6c99\u8054\u5408\u5316\u7597\u6cbb\u7597\u8fd9\u7c7b\u4fb5\u88ad\u6027\u53cc\u91cd\u7a81\u53d8\u7684\u6548\u679c\u3002<\/p>\n<p>\u7814\u7a76\u53d1\u73b0\uff0c\u52a0\u5165\u5316\u7597\u4f7f\u8fd9\u4e9b\u9ad8\u98ce\u9669\u60a3\u8005\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u7ffb\u4e86\u4e00\u756a\u3002\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u662f\u6307\u60a3\u8005\u5728\u764c\u75c7\u672a\u751f\u957f\u6216\u8fdb\u5c55\u7684\u60c5\u51b5\u4e0b\u751f\u5b58\u7684\u65f6\u95f4\u3002<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\">\u4f34TP53\u5171\u7a81\u53d8\u3001\u63a5\u53d7\u6cf0\u745e\u6c99\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e3a15.6\u4e2a\u6708\u3002<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\">\u4f34TP53\u5171\u7a81\u53d8\u3001\u63a5\u53d7\u6cf0\u745e\u6c99\u8054\u5408\u5316\u7597\u7684\u60a3\u8005\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u4e3a34.0\u4e2a\u6708\u3002<\/li>\n<\/ul>\n<p>\u901a\u8fc7\u5c06\u764c\u75c7\u8fdb\u5c55\u524d\u7684\u65f6\u95f4\u5ef6\u957f\u5230\u8fd1\u4e09\u5e74\uff0c\u8054\u5408\u65b9\u6848\u8bc1\u660e\u5b83\u53ef\u4ee5\u6709\u6548\u6291\u5236TP53\u7a81\u53d8\u7684\u4fb5\u88ad\u6027\uff0c\u4e3a\u4ee5\u5f80\u9884\u540e\u8f83\u5dee\u7684\u60a3\u8005\u5e26\u6765\u4e86\u91cd\u8981\u5e0c\u671b\u3002<\/p>\n<h2>\u7b56\u7565\u5bf9\u6bd4\u8868<br \/>\n<\/h2>\n<p>\u4e3a\u4e86\u76f4\u89c2\u5c55\u793a\u4e24\u79cd\u6cbb\u7597\u65b9\u6cd5\u7684\u5dee\u5f02\uff0c\u4e0b\u8868\u6bd4\u8f83\u4e86\u4e24\u79cd\u65b9\u6848\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\uff1a<\/p>\n<table style=\"height: 397px;\" width=\"1415\">\n<tbody>\n<tr>\n<td>\n<p>\u4e34\u5e8a\u7279\u5f81<\/p>\n<\/td>\n<td>\n<p>\u6cf0\u745e\u6c99\u5355\u836f\u6cbb\u7597\uff08\u4ec5\u670d\u836f\uff09<\/p>\n<\/td>\n<td>\n<p>\u6cf0\u745e\u6c99\uff0b\u5316\u7597\u8054\u5408\u6cbb\u7597<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>\u4e3b\u8981\u6cbb\u7597\u76ee\u6807<\/p>\n<\/td>\n<td>\n<p>\u957f\u671f\u9776\u5411\u63a7\u5236<\/p>\n<\/td>\n<td>\n<p>\u521d\u59cb\u5f3a\u5316\u4ee5\u9884\u9632\u8010\u836f<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\uff08FLAURA2\uff09<\/p>\n<\/td>\n<td>\n<p>37.6\u4e2a\u6708<\/p>\n<\/td>\n<td>\n<p>\u63a5\u8fd1\u56db\u5e74\uff0847.5\u4e2a\u6708\uff09<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>TP53\u5171\u7a81\u53d8\u7684\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\uff08TOP\u8bd5\u9a8c\uff09<\/p>\n<\/td>\n<td>\n<p>15.6\u4e2a\u6708<\/p>\n<\/td>\n<td>\n<p>34.0\u4e2a\u6708\uff08\u65f6\u95f4\u7ffb\u500d\uff09<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>\u7ed9\u836f\u65b9\u5f0f<\/p>\n<\/td>\n<td>\n<p>\u6bcf\u5929\u5728\u5bb6\u53e3\u670d\u4e00\u7247<\/p>\n<\/td>\n<td>\n<p>\u6bcf\u65e5\u53e3\u670d\u7247\u5242\uff0b4\u4e2a\u5468\u671f\u9759\u8109\u5316\u7597\uff0c\u968f\u540e\u8fdb\u884c\u7ef4\u6301\u5316\u7597\u8f93\u6ce8<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>\u4e3b\u8981\u526f\u4f5c\u7528<\/p>\n<\/td>\n<td>\n<p>\u901a\u5e38\u8f83\u8f7b\uff08\u76ae\u75b9\u3001\u8179\u6cfb\u3001\u76ae\u80a4\u5e72\u71e5\uff09<\/p>\n<\/td>\n<td>\n<p>\u4e2d\u5ea6\u81f3\u91cd\u5ea6\uff08\u75b2\u52b3\u3001\u6076\u5fc3\u3001\u8840\u7ec6\u80de\u51cf\u5c11\uff09<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2>FDA\u6279\u51c6\uff1a\u54ea\u4e9b\u60a3\u8005\u4ece\u8054\u5408\u6cbb\u7597\u4e2d\u83b7\u76ca\u6700\u591a\uff1f<br \/>\n<\/h2>\n<p>\u9274\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6210\u529f\uff0c\u76f8\u5173\u63aa\u65bd\u8fc5\u901f\u8ddf\u8fdb\u3002FDA\u6b63\u5f0f\u6279\u51c6\u5965\u5e0c\u66ff\u5c3c\u8054\u5408\u5316\u7597\u4f5c\u4e3aEGFR\u7a81\u53d8\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027NSCLC\u7684\u4e00\u7ebf\u6cbb\u7597\u3002<\/p>\n<p>\u5c3d\u7ba1\u8be5\u7597\u6cd5\u5df2\u83b7\u5e7f\u6cdb\u6279\u51c6\uff0c\u4f46\u6df1\u5165\u7684\u4e9a\u7ec4\u5206\u6790\u663e\u793a\uff0c\u90e8\u5206\u60a3\u8005\u80fd\u4ece\u4e2d\u83b7\u5f97\u6700\u5927\u76ca\u5904\u3002<\/p>\n<ol>\n<li> \u4f34\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\uff08CNS\uff09\u8f6c\u79fb\u7684\u60a3\u8005<\/li>\n<\/ol>\n<p>\u8111\u8f6c\u79fb\u5728\u665a\u671f\u80ba\u764c\u4e2d\u5f88\u5e38\u89c1\u3002\u7531\u4e8e\u8bb8\u591a\u836f\u7269\u65e0\u6cd5\u901a\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u8111\u8f6c\u79fb\u7684\u6cbb\u7597\u4e00\u76f4\u5f88\u56f0\u96be\u3002\u6cf0\u745e\u6c99\u867d\u80fd\u6709\u6548\u901a\u8fc7\u8840\u8111\u5c4f\u969c\uff0c\u4f46\u4e0e\u5316\u7597\u8054\u5408\u540e\u6291\u5236\u8111\u90e8\u80bf\u7624\u7684\u6548\u679c\u66f4\u597d\u3002<\/p>\n<ol start=\"2\">\n<li> \u4f3421\u53f7\u5916\u663e\u5b50L858R\u66ff\u4ee3\u7a81\u53d8\u7684\u60a3\u8005<\/li>\n<\/ol>\n<p>EGFR\u7a81\u53d8\u53ef\u5206\u4e3a\u4e24\u5927\u7c7b\uff1a19\u53f7\u5916\u663e\u5b50\u7f3a\u5931\u548c21\u53f7\u5916\u663e\u5b50L858R\u7a81\u53d8\u3002\u8fc7\u53bb\uff0c21\u53f7\u5916\u663e\u5b50\u7a81\u53d8\u7684\u80bf\u7624\u5355\u7528TKI\u6cbb\u7597\u7684\u53cd\u5e94\u901a\u5e38\u4e0d\u598219\u53f7\u5916\u663e\u5b50\u7a81\u53d8\u7684\u80bf\u7624\u3002<\/p>\n<p>FLAURA2\u7814\u7a76\u8bc1\u5b9e\uff0c\u52a0\u5165\u5316\u7597\u6709\u52a9\u4e8e\u5f25\u8865\u8fd9\u4e00\u4e0d\u8db3\u3002<\/p>\n<h2>\u526f\u4f5c\u7528\uff1a\u5e73\u8861\u7597\u6548\u4e0e\u751f\u6d3b\u8d28\u91cf<br \/>\n<\/h2>\n<p>\u5b89\u5168\u6027\u5bf9\u6bd4<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\">\u6cf0\u745e\u6c99\u5355\u836f\u6cbb\u7597\uff1a\u5927\u591a\u6570\u60a3\u8005\u5bf9\u5355\u72ec\u670d\u836f\u8010\u53d7\u826f\u597d\u3002\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94\u5305\u62ec\u8f7b\u5fae\u76ae\u75b9\u3001\u6307\u7532\u53d8\u8106\u3001\u8f7b\u5ea6\u8179\u6cfb\u548c\u75b2\u52b3\uff0c\u5bf9\u65e5\u5e38\u6d3b\u52a8\u5f71\u54cd\u5f88\u5c0f\u3002<\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\">\u6cf0\u745e\u6c99\u8054\u5408\u5316\u7597\uff1a\u8be5\u6cbb\u7597\u589e\u52a0\u4e86\u5316\u7597\u76f8\u5173\u7684\u7ec6\u80de\u6bd2\u6027\u526f\u4f5c\u7528\uff0c\u5305\u62ec\u75b2\u52b3\u52a0\u91cd\u3001\u6076\u5fc3\u3001\u8131\u53d1\uff08\u5934\u53d1\u53d8\u7a00\uff09\u548c\u6682\u65f6\u6027\u8840\u6db2\u6bd2\u6027\u3002\u5316\u7597\u4f1a\u6682\u65f6\u5f71\u54cd\u9aa8\u9ad3\u529f\u80fd\uff0c\u5bfc\u81f4\u8d2b\u8840\uff08\u7ea2\u7ec6\u80de\u51cf\u5c11\u5f15\u8d77\u7684\u75b2\u5026\uff09\u548c\u4e2d\u6027\u7c92\u7ec6\u80de\u51cf\u5c11\uff08\u767d\u7ec6\u80de\u51cf\u5c11\uff0c\u66f4\u6613\u611f\u67d3\uff09\u3002<\/li>\n<\/ul>\n<h3>\u901a\u8fc7\u652f\u6301\u6cbb\u7597\u5ea6\u8fc7\u7597\u7a0b<br \/>\n<\/h3>\n<p>\u5fc5\u987b\u660e\u767d\uff0c\u5316\u7597\u5728\u6574\u4e2a\u6cbb\u7597\u4e2d\u53ea\u662f\u6682\u65f6\u7684\u3002\u901a\u5e38\u60a3\u8005\u53ea\u9700\u63a5\u53d74\u4e2a\u5468\u671f\uff08\u7ea6\u6bcf3\u5468\u4e00\u6b21\uff09\u7684\u5f3a\u5316\u5316\u7597\u3002<\/p>\n<p>\u5b8c\u6210\u8fd9\u4e00\u9636\u6bb5\u540e\uff0c\u60a3\u8005\u8fdb\u5165\u7ef4\u6301\u6cbb\u7597\uff0c\u6bd2\u6027\u660e\u663e\u964d\u4f4e\u3002<\/p>\n<p>\u80bf\u7624\u79d1\u533b\u751f\u4f1a\u79ef\u6781\u91c7\u53d6\u652f\u6301\u6cbb\u7597\u63aa\u65bd\u51cf\u8f7b\u526f\u4f5c\u7528\uff0c\u5305\u62ec\u5316\u7597\u524d\u4f7f\u7528\u5f3a\u6548\u6b62\u5410\u836f\uff0c\u4ee5\u53ca\u6ce8\u5c04\u57f9\u975e\u683c\u53f8\u4ead\u7b49\u751f\u957f\u56e0\u5b50\u3002<\/p>\n<h2>\u7ed3\u8bba\uff1a\u5171\u540c\u51b3\u7b56<br \/>\n<\/h2>\n<p>FLAURA2\u548cTOP\u8bd5\u9a8c\u7684\u7ed3\u679c\u6781\u5927\u5730\u6539\u53d8\u4e86\u533b\u5b66\u754c\u5e94\u5bf9\u665a\u671f\u80ba\u764c\u7684\u65b9\u5f0f\u3002<\/p>\n<p>\u5982\u4eca\u53ef\u4ee5\u786e\u5b9a\uff0c\u6cf0\u745e\u6c99\u8054\u5408\u5316\u7597\u53ef\u5c06\u4e2d\u4f4d\u603b\u751f\u5b58\u671f\u5ef6\u957f\u81f3\u8fd1\u56db\u5e74\uff0847.5\u4e2a\u6708\uff09\uff0c\u5e76\u4f7f\u4f34TP53\u5171\u7a81\u53d8\u7684\u60a3\u8005\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u7ffb\u500d\uff0834.0\u4e2a\u6708\u5bf9\u6bd415.6\u4e2a\u6708\uff09\u3002<\/p>\n<p>\u9009\u62e9\u5355\u836f\u6cbb\u7597\u8fd8\u662f\u8054\u5408\u6cbb\u7597\uff0c\u5e94\u4e0e\u60a8\u7684\u80bf\u7624\u79d1\u533b\u751f\u5766\u8bda\u8ba8\u8bba\u3002<\/p>\n<p>\u5982\u679c\u60a8\u8eab\u4f53\u72b6\u51b5\u826f\u597d\uff0c\u5e76\u5e0c\u671b\u957f\u671f\u63a7\u5236\u80bf\u7624\uff0c\u4ece\u4e00\u5f00\u59cb\u5c31\u8fdb\u884c\u8054\u5408\u6cbb\u7597\u662f\u4e0d\u9519\u7684\u9009\u62e9\u3002<\/p>\n<p>\u5982\u679c\u60a8\u8eab\u4f53\u8f83\u5f31\u6216\u5e0c\u671b\u65e5\u5e38\u6cbb\u7597\u66f4\u6e29\u548c\uff0c\u4ece\u6cf0\u745e\u6c99\u5355\u836f\u5f00\u59cb\u4e5f\u662f\u597d\u7684\u9009\u62e9\u3002<\/p>\n<h2>FAQ<\/h2>\n<h3>1. \u5982\u679c\u6211\u5148\u5355\u7528\u6cf0\u745e\u6c99\uff0c\u80bf\u7624\u8fdb\u5c55\u540e\u80fd\u518d\u52a0\u5316\u7597\u5417\uff1f<br \/>\n<\/h3>\n<p>\u60a8\u968f\u65f6\u53ef\u4ee5\u5728\u4e8c\u7ebf\u6cbb\u7597\u65f6\u9009\u62e9\u5316\u7597\uff0c\u4f46FLAURA2\u8bd5\u9a8c\u7684\u7ed3\u679c\u6e05\u695a\u8868\u660e\uff0c\u4ece\u4e00\u5f00\u59cb\u5c31\u63a5\u53d7\u8054\u5408\u6cbb\u7597\u8981\u6709\u76ca\u5f97\u591a\u3002<\/p>\n<h3>2. \u5982\u4f55\u77e5\u9053\u6211\u662f\u5426\u6709TOP\u8bd5\u9a8c\u4e2d\u63d0\u5230\u7684\u9ad8\u98ce\u9669TP53\u7a81\u53d8\uff1f<br \/>\n<\/h3>\n<p>\u8fd9\u53ef\u4ee5\u4ece\u60a8\u7684\u65b0\u4e00\u4ee3\u6d4b\u5e8f\uff08NGS\uff09\u5168\u9762\u751f\u7269\u6807\u5fd7\u7269\u68c0\u6d4b\u7ed3\u679c\u4e2d\u83b7\u5f97\u3002<\/p>\n<p>\u8fd9\u662f\u5728\u521d\u6b21\u8bca\u65ad\u65f6\u5bf9\u60a8\u7684\u8840\u6db2\u6216\u7ec4\u7ec7\u6837\u672c\u8fdb\u884c\u7684\u57fa\u56e0\u68c0\u6d4b\u3002\u60a8\u53ef\u4ee5\u968f\u65f6\u8bf7\u533b\u751f\u4e0e\u60a8\u8ba8\u8bba\u68c0\u6d4b\u5230\u7684\u5171\u7a81\u53d8\u60c5\u51b5\u3002<\/p>\n<h3>3. \u8054\u5408\u6cbb\u7597\u671f\u95f4\u6211\u4f1a\u6389\u5149\u5934\u53d1\u5417\uff1f<br \/>\n<\/h3>\n<p>\u57f9\u7f8e\u66f2\u585e\u548c\u5361\u94c2\u7b49\u6297\u764c\u836f\u7269\u53ef\u80fd\u5bfc\u81f4\u5934\u53d1\u53d8\u7a00\u548c\u8131\u843d\uff0c\u4f46\u4e0d\u4f1a\u50cf\u4e73\u817a\u764c\u548c\u5375\u5de2\u764c\u7684\u5f3a\u5316\u6cbb\u7597\u90a3\u6837\u5b8c\u5168\u8131\u53d1\u3002\u5b8c\u6210\u524d\u56db\u4e2a\u5316\u7597\u5468\u671f\u540e\uff0c\u5934\u53d1\u4f1a\u91cd\u65b0\u957f\u9f50\u3002<\/p>\n<h2>\u53c2\u8003\u6587\u732e <\/h2>\n<ul>\n<li aria-level=\"1\">\u963f\u65af\u5229\u5eb7\u65b0\u95fb\u4e2d\u5fc3:<a href=\"https:\/\/www.astrazeneca.com\/media-centre\/press-releases\/2025\/tagrisso-plus-chemotherapy-demonstrated-a-median-overall-survival-of-nearly-four-years.html\" target=\"_blank\" rel=\"noopener nofollow\"> \u6cf0\u745e\u6c99\u8054\u5408\u5316\u7597\u5b9e\u73b0\u8fd1\u56db\u5e74\u7684\u4e2d\u4f4d\u603b\u751f\u5b58\u671f<\/a><\/li>\n<li aria-level=\"1\">\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\uff08NEJM\uff09:<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2304594\" target=\"_blank\" rel=\"noopener nofollow\"> \u5965\u5e0c\u66ff\u5c3c\u8054\u5408\u6216\u4e0d\u8054\u5408\u5316\u7597\u6cbb\u7597EGFR\u7a81\u53d8\u665a\u671fNSCLC\uff08FLAURA2\uff09<\/a><\/li>\n<li aria-level=\"1\">\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09:<a href=\"https:\/\/www.fda.gov\/drugs\/resources-information-approved-drugs\/fda-approves-osimertinib-chemotherapy-egfr-mutated-non-small-cell-lung-cancer\" target=\"_blank\" rel=\"noopener nofollow\"> FDA\u6279\u51c6\u5965\u5e0c\u66ff\u5c3c\u8054\u5408\u5316\u7597\u6cbb\u7597EGFR\u7a81\u53d8\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/a><\/li>\n<li aria-level=\"1\">Oncology News Central\uff0fOncLive:<a href=\"https:\/\/www.onclive.com\/view\/osimertinib-plus-chemotherapy-doubles-pfs-in-egfr--tp53-mutant-advanced-nsclc\" rel=\"nofollow noopener\" target=\"_blank\"> TOP\u8bd5\u9a8c\u5206\u6790\uff1a\u5965\u5e0c\u66ff\u5c3c\u8054\u5408\u5316\u7597\u4f7f\u9ad8\u98ce\u9669EGFR\/TP53\u7a81\u53d8\u4e9a\u7ec4\u7684\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u7ffb\u500d<\/a><\/li>\n<li aria-level=\"1\">NCBI Bookshelf:<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/BK596656\/\" target=\"_blank\" rel=\"noopener nofollow\"> \u5965\u5e0c\u66ff\u5c3c\u6982\u51b5\u53ca\u5176\u5728\u7cbe\u51c6\u80bf\u7624\u5b66\u4e2d\u7684\u5e94\u7528<\/a><\/li>\n<\/ul>\n<h2>\u76f8\u5173\u9605\u8bfb\u4e0e\u8d44\u6e90<br \/>\n<\/h2>\n<p><em>\u5982\u679c\u60a8\u60f3\u6df1\u5165\u4e86\u89e3\u8fd9\u79cd\u836f\u7269\u7684\u4f5c\u7528\u539f\u7406\u3001\u8d39\u7528\u9009\u62e9\u6216\u65e5\u5e38\u62a4\u7406\uff0c\u8bf7\u9605\u8bfb\u4ee5\u4e0b\u60a3\u8005\u6307\u5357\uff1a<\/em><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><em><b>\u4eff\u5236\u6cf0\u745e\u6c99\uff08\u5965\u5e0c\u66ff\u5c3c\uff09\u5982\u4f55\u6cbb\u7597\u80ba\u764c<\/b><b><br \/><\/b>\u4e86\u89e3\u5965\u5e0c\u66ff\u5c3c\u9776\u5411\u80bf\u7624\u7ec6\u80de\u3001\u963b\u6b62\u5176\u589e\u6b96\u7684\u5fae\u89c2\u79d1\u5b66\u539f\u7406\u3002<\/em><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><em><a href=\"https:\/\/indogenmed.org\/zh-hans\/resource\/why-tagrisso-expensive-generic-alternatives-tagrisso\/\"><b>\u6cf0\u745e\u6c99\u4e3a\u4ec0\u4e48\u8fd9\u4e48\u8d35\uff1f\u4e86\u89e3\u6cf0\u745e\u6c99\u7684\u4eff\u5236\u66ff\u4ee3\u836f<\/b><b><br \/><\/b><\/a>\u900f\u660e\u89e3\u6790\u80bf\u7624\u836f\u7269\u5b9a\u4ef7\u3001\u8de8\u56fd\u4fdd\u9669\u529e\u7406\uff0c\u4ee5\u53ca\u5982\u4f55\u5b89\u5168\u83b7\u5f97\u4ef7\u683c\u5b9e\u60e0\u7684\u4f18\u8d28\u4eff\u5236\u836f\u3002<\/em><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><em><a href=\"https:\/\/indogenmed.org\/zh-hans\/resource\/osimertinib-first-line-therapy-approvals-for-lung-cancer\/\"><b>\u5965\u5e0c\u66ff\u5c3c\u4f5c\u4e3a\u4e00\u7ebf\u6cbb\u7597\uff1a\u80ba\u764c\u60a3\u8005\u7684\u5173\u952e\u6279\u51c6\u4e0e\u83b7\u76ca<\/b><b><br \/><\/b><\/a>\u4e86\u89e3\u5168\u7403\u536b\u751f\u76d1\u7ba1\u673a\u6784\u4e3a\u4f55\u5c06\u8fd9\u79cd\u836f\u7269\u5b9a\u4e3aEGFR\u7a81\u53d8\u80bf\u7624\u7684\u521d\u59cb\u6807\u51c6\u6cbb\u7597\u3002<\/em><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><em><a href=\"https:\/\/indogenmed.org\/zh-hans\/resource\/osimertinib-side-effects-common-long-term-risks\/\"><b>\u5965\u5e0c\u66ff\u5c3c\u7684\u526f\u4f5c\u7528\uff1a\u5e38\u89c1\u3001\u4e25\u91cd\u53ca\u957f\u671f\u98ce\u9669<\/b><b><br \/><\/b><\/a>\u4e00\u4efd\u4ee5\u60a3\u8005\u4e3a\u4e2d\u5fc3\u7684\u5b9e\u7528\u624b\u518c\uff0c\u6559\u60a8\u8ffd\u8e2a\u75c7\u72b6\u3001\u5728\u5bb6\u5904\u7406\u76ae\u75b9\u6216\u8179\u6cfb\uff0c\u5e76\u5728\u6cbb\u7597\u671f\u95f4\u4fdd\u62a4\u91cd\u8981\u5668\u5b98\u3002<\/em><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u665a\u671f\u80ba\u764c\u7684\u6cbb\u7597\u53d6\u5f97\u4e86\u91cd\u5927\u8fdb\u5c55\u3002\u591a\u5e74\u6765\uff0c\u60a3\u8005\u53ea\u80fd\u4f9d\u9760\u4f20\u7edf\u5316\u7597\uff0c\u5b83\u867d\u80fd\u6e05\u9664\u764c\u7ec6\u80de\uff0c\u5374\u4f1a\u7ed9\u5168\u8eab\u5e26\u6765\u8bf8\u591a\u526f\u4f5c\u7528\u3002 \u7cbe\u51c6 [&hellip;]<\/p>\n","protected":false},"author":2144,"featured_media":134507,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6122,5954],"tags":[],"class_list":["post-134500","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer-medicine","category-generic-drugs"],"_links":{"self":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts\/134500","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/users\/2144"}],"replies":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/comments?post=134500"}],"version-history":[{"count":0,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts\/134500\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/media\/134507"}],"wp:attachment":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/media?parent=134500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/categories?post=134500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/tags?post=134500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}