{"id":39442,"date":"2025-03-20T11:46:00","date_gmt":"2025-03-20T11:46:00","guid":{"rendered":"https:\/\/indogenmed.org\/resource\/osimertinib-side-effects-common-severe-and-long-term-risks-you-should-know\/"},"modified":"2026-07-03T17:24:29","modified_gmt":"2026-07-03T17:24:29","slug":"osimertinib-side-effects-common-long-term-risks","status":"publish","type":"post","link":"https:\/\/indogenmed.org\/zh-hans\/resource\/osimertinib-side-effects-common-long-term-risks\/","title":{"rendered":"\u5965\u5e0c\u66ff\u5c3c\u526f\u4f5c\u7528\uff1a\u5e38\u89c1\u3001\u4e25\u91cd\u548c\u957f\u671f\u98ce\u9669\uff0c\u60a8\u5e94\u8be5\u4e86\u89e3"},"content":{"rendered":"<p>\u533b\u751f\u901a\u5e38\u4f1a\u5f00\u5177<a href=\"\/molecule\/osimertinib\/\" target=\"_blank\" rel=\"noopener\">\u5965\u5e0c\u66ff\u5c3c<\/a>\u6765\u6cbb\u7597\u4e0e\u7279\u5b9a EGFR\uff08\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff09\u7a81\u53d8\u76f8\u5173\u7684\u80ba\u764c\u3002\u7136\u800c\uff0c\u5b83\u7684\u5f71\u54cd\u8fdc\u4e0d\u6b62\u4e8e\u6b64\u3002\u867d\u7136\u5965\u5e0c\u66ff\u5c3c\u7684\u4e00\u4e9b\u526f\u4f5c\u7528\u8f83\u8f7b\u3001\u77ed\u6682\u4e14\u53ef\u81ea\u884c\u6d88\u9000\uff0c\u4f46\u53e6\u4e00\u4e9b\u526f\u4f5c\u7528\u53ef\u80fd\u66f4\u4e25\u91cd\u6216\u6301\u7eed\u5b58\u5728\u3002\u6709\u4e9b\u95ee\u9898\u53ef\u80fd\u65e9\u671f\u51fa\u73b0\uff0c\u800c\u53e6\u4e00\u4e9b\u5219\u5728\u957f\u671f\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u540e\u624d\u4f1a\u51fa\u73b0\u3002\u4e86\u89e3\u8fd9\u4e9b\u6f5c\u5728\u7684\u5965\u5e0c\u66ff\u5c3c\u526f\u4f5c\u7528\u6709\u52a9\u4e8e\u505a\u51fa\u660e\u667a\u7684\u51b3\u5b9a\u5e76\u6709\u6548\u7ba1\u7406\u5065\u5eb7\u72b6\u51b5\u3002<\/p>\n<h2>\u5965\u5e0c\u66ff\u5c3c\u662f\u4ec0\u4e48\uff1f<\/h2>\n<p>\u5965\u5e0c\u66ff\u5c3c\u662f\u4e00\u79cd\u7528\u4e8e\u6cbb\u7597\u67d0\u4e9b\u4e0e\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53 (EGFR) \u7a81\u53d8\u76f8\u5173\u7684<a href=\"\/zh-hans\/medicine\/lung-cancer\/\" target=\"_blank\" rel=\"noopener\">\u80ba\u764c<\/a>\u7684\u836f\u7269\u3002\u5b83\u901a\u5e38\u4ee5\u5546\u54c1\u540d\u6cf0\u745e\u6c99 ( <a href=\"\/zh-hans\/product\/tagrisso-40-mg-tablets\/\">Tagrisso)<\/a>\u51fa\u552e\uff0c\u5176\u4f5c\u7528\u673a\u5236\u662f\u963b\u6b62\u5bfc\u81f4\u764c\u7ec6\u80de\u5feb\u901f\u751f\u957f\u548c\u589e\u6b96\u7684\u86cb\u767d\u8d28\u7684\u4ea7\u751f\u3002\u7b80\u800c\u8a00\u4e4b\uff0c\u5b83\u6709\u52a9\u4e8e\u51cf\u7f13\u751a\u81f3\u963b\u6b62\u764c\u7ec6\u80de\u7684\u751f\u957f\uff0c\u56e0\u6b64\u662f\u4e00\u79cd\u6709\u6548\u7684\u6cbb\u7597\u9009\u62e9\u3002\u5965\u5e0c\u66ff\u5c3c\u4e5f\u53ef\u80fd\u7528\u4e8e\u6cbb\u7597\u5176\u4ed6\u75be\u75c5\uff0c\u56e0\u6b64\u5728\u670d\u7528\u524d\u52a1\u5fc5\u54a8\u8be2\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u6216\u836f\u5242\u5e08\u3002<\/p>\n<h2>\u4e3a\u4ec0\u4e48\u8981\u4f7f\u7528\u5965\u5e0c\u66ff\u5c3c\uff1f<\/h2>\n<p>\u8bf7\u9605\u8bfb\u4ee5\u4e0b\u90e8\u5206\uff0c\u4e86\u89e3\u533b\u751f\u4e3a\u4f55\u5f00\u5177\u6b64\u836f\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u533b\u751f\u5efa\u8bae\u670d\u7528\u6cf0\u745e\u6c99\uff08\u5965\u5e0c\u66ff\u5c3c\uff09\u6cbb\u7597\u67d0\u4e9b\u643a\u5e26\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u7a81\u53d8\u7684\u80ba\u764c\u60a3\u8005\u3002EGFR\u662f\u4e00\u79cd\u4f4d\u4e8e\u7ec6\u80de\u8868\u9762\u7684\u86cb\u767d\u8d28\u5c42\uff0c\u5728\u764c\u7ec6\u80de\u7684\u751f\u957f\u548c\u589e\u6b96\u4e2d\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5f53EGFR\u53d1\u751f\u7a81\u53d8\u65f6\uff0c\u764c\u7ec6\u80de\u4f1a\u8fc5\u901f\u751f\u957f\u548c\u589e\u6b96\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u533b\u751f\u901a\u5e38\u5efa\u8bae\u4f7f\u7528\u6cf0\u745e\u6c99\uff08\u5965\u5e0c\u66ff\u5c3c\uff09\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\uff0c\u6216\u4e0e\u5176\u4ed6\u6709\u6548\u836f\u7269\u8054\u5408\u4f7f\u7528\uff0c\u4ee5\u4e13\u95e8\u9776\u5411EGFR\u7a81\u53d8\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5965\u5e0c\u66ff\u5c3c\u53ef\u7528\u4e8e\u6cbb\u7597\u5df2\u6269\u6563\u81f3\u90bb\u8fd1\u7ec4\u7ec7\u4e14\u65e0\u6cd5\u901a\u8fc7\u624b\u672f\u5207\u9664\u7684\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002\u5b83\u6700\u9002\u7528\u4e8e\u5df2\u63a5\u53d7\u8fc7\u5316\u7597\u548c\u653e\u7597\u7684\u60a3\u8005\u3002<\/p>\n<\/li>\n<\/ul>\n<h2>\u5b83\u662f\u5982\u4f55\u8fd0\u4f5c\u7684\uff1f<\/h2>\n<p>\u5965\u5e0c\u66ff\u5c3c\uff08\u5965\u5e0c\u66ff\u5c3c\u6216\u6cf0\u745e\u6c99\uff09\u9776\u5411\u764c\u7ec6\u80de\u8868\u9762\u7684\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff08EGFR\uff09\u86cb\u767d\u3002\u8fd9\u4e9b\u86cb\u767d\u5728\u4fc3\u8fdb\u764c\u7ec6\u80de\u751f\u957f\u548c\u589e\u6b96\u65b9\u9762\u8d77\u7740\u81f3\u5173\u91cd\u8981\u7684\u4f5c\u7528\u3002\u5982\u679c\u60a8\u60a3\u6709EGFR\u7a81\u53d8\u7684\u764c\u75c7\uff0c\u5219\u88ab\u8ba4\u4e3a\u662fEGFR\u9633\u6027\uff0c\u8fd9\u79cd\u836f\u7269\u65e8\u5728\u9776\u5411\u5e76\u6cbb\u7597\u8fd9\u79cd\u7279\u5b9a\u7684\u7a81\u53d8\u3002\u533b\u751f\u4f1a\u5728\u5f00\u5177\u6b64\u836f\u524d\u8981\u6c42\u60a8\u8fdb\u884c\u4e00\u4e9b\u68c0\u67e5\uff0c\u4ee5\u786e\u5b9a\u662f\u5426\u5b58\u5728\u8fd9\u4e9b\u53d7\u4f53\u3002\u5965\u5e0c\u66ff\u5c3c\u53ef\u4ee5\u5e2e\u52a9\u9650\u5236\u764c\u75c7\u7684\u6269\u6563\u6216\u963b\u6b62\u5176\u751f\u957f\uff0c\u5c24\u5176\u662f\u5728\u764c\u75c7\u665a\u671f\u3002\u5728\u67d0\u4e9b\u60c5\u51b5\u4e0b\uff0c\u5b83\u8fd8\u53ef\u4ee5\u7528\u4e8e\u9884\u9632\u624b\u672f\u540e\u764c\u75c7\u590d\u53d1\uff0c\u4ece\u800c\u63d0\u4f9b\u989d\u5916\u7684\u4fdd\u62a4\uff0c\u9632\u6b62\u75be\u75c5\u590d\u53d1\u3002<\/p>\n<h2>\u670d\u7528\u6b64\u836f\u524d\u60a8\u5e94\u8be5\u544a\u8bc9\u533b\u751f\u4ec0\u4e48\uff1f<\/h2>\n<p>\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u9700\u8981\u4e86\u89e3\u60a8\u662f\u5426\u60a3\u6709\u4ee5\u4e0b\u4efb\u4f55\u75be\u75c5\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u810f\u75c5<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u65e2\u5f80\u8840\u6db2\u75be\u75c5\u53f2\uff0c\u4f8b\u5982\u518d\u751f\u969c\u788d\u6027\u8d2b\u8840<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8840\u6db2\u4e2d\u9541\u3001\u94be\u6216\u94a0\u7684\u542b\u91cf\u8fc7\u9ad8\u6216\u8fc7\u4f4e<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u75c5<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u80ba\u529f\u80fd\u969c\u788d<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u8df3\u6216\u8282\u5f8b\u4e0d\u89c4\u5219<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u60a8\u76ee\u524d\u6b63\u5728\u670d\u7528\u7684\u5176\u4ed6\u836f\u7269\u6216\u8865\u5145\u5242<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6000\u5b55\u6216\u6b63\u5728\u5907\u5b55<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u54fa\u4e73<\/p>\n<\/li>\n<\/ul>\n<h2>\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528<\/h2>\n<p>\u4ee5\u4e0b\u662f\u5965\u5e0c\u66ff\u5c3c\u6700\u5e38\u89c1\u7684\u526f\u4f5c\u7528\u5217\u8868\u3002\u5982\u679c\u60a8\u6301\u7eed\u51fa\u73b0\u4ee5\u4e0b\u4efb\u4f55\u75c7\u72b6\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u751f\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8840\u6db2\u75be\u75c5<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u75b9<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8179\u6cfb<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6307\u7532\u51fa\u73b0\u80bf\u80c0\u3001\u75bc\u75db\u3001\u53d1\u7ea2\u3001\u65ad\u88c2\u3001\u5206\u79bb\u6216\u4ece\u7532\u5e8a\u4e0a\u8131\u843d\u7b49\u53d8\u5316\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u808c\u8089\u6216\u9aa8\u9abc\u75bc\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u75b2\u5026<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5e72\u6027\u76ae\u80a4<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u53e3\u8154\u6e83\u75a1<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u7126\u8651<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u80f8\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5934\u6655\u6216\u660f\u53a5<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u7a81\u7136\uff0c\u4e00\u9635\u5267\u70c8\u7684\u5934\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u547c\u5438\u56f0\u96be<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u624b\u81c2\u6216\u817f\u90e8\u65e0\u529b\u6216\u9ebb\u6728<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u53e3\u9f7f\u4e0d\u6e05<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u4fbf\u79d8<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u7619\u75d2<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u80a4\u5e72\u71e5\u6216\u76b2\u88c2<\/p>\n<\/li>\n<\/ul>\n<h3>\u5965\u5e0c\u66ff\u5c3c\u4e0d\u5e38\u89c1\u7684\u526f\u4f5c\u7528<\/h3>\n<p>\u867d\u7136\u4e0d\u592a\u5e38\u89c1\uff0c\u4f46\u5965\u5e0c\u66ff\u5c3c\u6700\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u6982\u8ff0\u5982\u4e0b\u3002\u8bf7\u4ed4\u7ec6\u9605\u8bfb\u4ee5\u4e0b\u4fe1\u606f\uff0c\u4e86\u89e3\u5982\u679c\u51fa\u73b0\u8fd9\u4e9b\u526f\u4f5c\u7528\u8be5\u5982\u4f55\u5e94\u5bf9\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94\uff1a\u670d\u7528\u6cf0\u745e\u6c99\u540e\uff0c\u53ef\u80fd\u4f1a\u51fa\u73b0\u4e00\u4e9b\u4e25\u91cd\u7684\u8fc7\u654f\u53cd\u5e94\u3002\u5982\u679c\u60a8\u51fa\u73b0\u4ee5\u4e0b\u4efb\u4f55\u4e25\u91cd\u8fc7\u654f\u53cd\u5e94\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u505c\u6b62\u670d\u7528\u5e76\u54a8\u8be2\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\uff1a<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5173\u8282\u75bc\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u547c\u5438\u56f0\u96be\u6216\u5598\u606f<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u5f8b\u4e0d\u9f50<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6dcb\u5df4\u7ed3\u80bf\u5927<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6076\u5fc3\u6216\u5455\u5410<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u80c3\u75c9\u631b<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u9762\u90e8\u3001\u5634\u5507\u3001\u53e3\u8154\u3001\u820c\u5934\u6216\u5589\u5499\u80bf\u80c0<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u53d1\u70e7\u6216\u5168\u8eab\u4e0d\u9002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u80a4\u7619\u75d2\u3001\u76ae\u75b9\u6216\u76ae\u80a4\u4e0a\u51fa\u73b0\u6de1\u7ea2\u8272\u80bf\u5757\u88ab\u79f0\u4e3a\u8368\u9ebb\u75b9\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u541e\u54bd\u56f0\u96be\u6216\u5589\u5499\u7d27\u7ef7<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u80ba\u90e8\u708e\u75c7\uff1a\u95f4\u8d28\u6027\u80ba\u75c5\u6216\u80ba\u90e8\u708e\u75c7\u662f\u5965\u5e0c\u66ff\u5c3c\u7684\u53e6\u4e00\u4e2a\u4e25\u91cd\u526f\u4f5c\u7528\u3002\u5982\u679c\u957f\u671f\u4e0d\u6cbb\u7597\uff0c\u53ef\u80fd\u4f1a\u5371\u53ca\u751f\u547d\u3002\u5982\u679c\u60a8\u51fa\u73b0\u547c\u5438\u56f0\u96be\u3001\u6c14\u77ed\u3001\u5598\u606f\u6216\u80f8\u95f7\u7b49\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u5c31\u533b\u3002\u6301\u7eed\u54b3\u55fd\u548c\/\u6216\u53d1\u70e7\u4e5f\u662f\u80ba\u90e8\u708e\u75c7\u7684\u75c7\u72b6\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u5f8b\u5931\u5e38\uff1a\u670d\u7528\u6cf0\u745e\u7d22\u53ef\u80fd\u5bfc\u81f4\u5fc3\u5f8b\u5931\u5e38\uff0c\u8fdb\u800c\u5f15\u8d77\u5fc3\u5f8b\u4e0d\u9f50\u548c\u6655\u53a5\u3002\u8fd9\u53ef\u80fd\u5bfc\u81f4\u5fc3\u810f\u9aa4\u505c\uff0c\u5373\u5fc3\u810f\u7a81\u7136\u505c\u6b62\u8df3\u52a8\u3002\u5982\u679c\u60a8\u51fa\u73b0\u4ee5\u4e0b\u4efb\u4f55\u5fc3\u810f\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u5bfb\u6c42\u7d27\u6025\u533b\u7597\u6551\u52a9\uff1a<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5267\u70c8\u80f8\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u611f\u5230\u5934\u6655\u3001\u5934\u660f\u6216\u6655\u53a5<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u7387\u53d8\u5316\u53ef\u80fd\u5305\u62ec\u5fc3\u8df3\u8fc7\u5feb\u6216\u8fc7\u6162\uff0c\u6709\u65f6\u4f60\u53ef\u80fd\u4f1a\u611f\u5230\u5fc3\u8df3\u5267\u70c8\u6216\u6f0f\u8df3\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u4e25\u91cd\u7684\u76ae\u80a4\u53cd\u5e94\uff1a\u867d\u7136\u5965\u5e0c\u66ff\u5c3c\u662f\u6cbb\u7597 EGFR \u9633\u6027\u80ba\u764c\u7684\u6709\u6548\u836f\u7269\uff0c\u4f46\u5fc5\u987b\u6ce8\u610f\u5176\u53ef\u80fd\u51fa\u73b0\u7684\u4e25\u91cd\u526f\u4f5c\u7528\uff0c\u5305\u62ec\u53f2\u8482\u6587\u65af-\u7ea6\u7ff0\u900a\u7efc\u5408\u5f81 (SJS) \u548c\u4e2d\u6bd2\u6027\u8868\u76ae\u574f\u6b7b\u677e\u89e3\u75c7 (TEN)\u3002\u8fd9\u4e9b\u90fd\u662f\u4e25\u91cd\u7684\u76ae\u80a4\u53cd\u5e94\uff0c\u5982\u4e0d\u53ca\u65f6\u6cbb\u7597\u53ef\u80fd\u5371\u53ca\u751f\u547d\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u75bc\u75db\u7684\u76ae\u80a4<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u80a4\u5448\u7ea2\u8272\u6216\u7d2b\u8272\uff0c\u770b\u8d77\u6765\u50cf\u70e7\u4f24\u4e86\u4e00\u6837\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u80a4\u3001\u751f\u6b96\u5668\u3001\u53e3\u8154\u548c\u9f3b\u5b50\u51fa\u73b0\u7ea2\u8272\u76ae\u75b9\u6216\u6c34\u75b1<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u775b\u75bc\u75db\u3001\u6d41\u6cea\u3001\u53d1\u7ea2<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8840\u6db2\u7cfb\u7edf\u75be\u75c5\uff1a\u90e8\u5206\u60a3\u8005\u5728\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u4e00\u6bb5\u65f6\u95f4\u540e\u4f1a\u51fa\u73b0\u8840\u6db2\u611f\u67d3\u3002\u8fd9\u4e9b\u75be\u75c5\u5305\u62ec\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\uff08\u8840\u5c0f\u677f\u8ba1\u6570\u4f4e\uff09\u3001\u767d\u7ec6\u80de\u51cf\u5c11\u75c7\uff08\u767d\u7ec6\u80de\u8ba1\u6570\u4f4e\uff09\u548c\u518d\u751f\u969c\u788d\u6027\u8d2b\u8840\u3002\u5982\u679c\u60a8\u51fa\u73b0\u4ee5\u4e0b\u4efb\u4f55\u75c7\u72b6\uff0c\u8bf7\u52ff\u670d\u7528\u6cf0\u745e\u6c99\uff08Tagrisso\uff09\u5e76\u7acb\u5373\u5c31\u533b\uff1a<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u76ae\u80a4\u82cd\u767d\u6216\u6cdb\u9ec4<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u51fa\u8840\u6216\u5bb9\u6613\u7600\u4f24<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u9891\u7e41\u7684\u8840\u6db2\u611f\u67d3<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5934\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u5f8b\u5f02\u5e38<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u611f\u89c9\u81ea\u5df1\u5feb\u8981\u6655\u5012\u4e86<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u4e25\u91cd\u7684\u514d\u75ab\u7cfb\u7edf\u53cd\u5e94\uff1a\u670d\u7528\u6cf0\u745e\u6c99\u540e\uff0c\u90e8\u5206\u60a3\u8005\u53ef\u80fd\u4f1a\u51fa\u73b0\u809d\u810f\u3001\u8840\u7ba1\u6216\u6dcb\u5df4\u7ba1\u708e\u75c7\u3002\u8fd9\u79cd\u514d\u75ab\u7cfb\u7edf\u53cd\u5e94\u4e5f\u79f0\u4e3a\u76ae\u80a4\u8840\u7ba1\u708e\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u9664\u6b64\u4e4b\u5916\uff0c\u90e8\u5206\u60a3\u8005\u8fd8\u4f1a\u51fa\u73b0\u8368\u9ebb\u75b9\u6027\u8840\u7ba1\u708e\u3001\u767d\u7ec6\u80de\u7834\u788e\u6027\u8840\u7ba1\u708e\u548cIgA\u8840\u7ba1\u708e\u3002\u5982\u679c\u60a8\u53d1\u73b0\u4ee5\u4e0b\u4efb\u4f55\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u505c\u6b62\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u5e76\u54a8\u8be2\u533b\u751f\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u7d2b\u8272\u6591\u70b9\uff0c\u53d1\u7ea2<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6309\u538b\u540e\u4ecd\u4e0d\u892a\u8272\u7684\u76ae\u80a4\u53d8\u8272<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8eab\u4f53\u5927\u9762\u79ef\uff08\u8eaf\u5e72\uff09\u51fa\u73b0\u5927\u7247\u8368\u9ebb\u75b9<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u4e25\u91cd\u76ae\u75b9<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5173\u8282\u75bc\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u6301\u7eed\u53d1\u70ed<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u957f\u65f6\u95f4\u7684\u75b2\u52b3<\/p>\n<\/li>\n<\/ul>\n<h3>\u5965\u5e0c\u66ff\u5c3c\u7f55\u89c1\u526f\u4f5c\u7528<\/h3>\n<p>\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u6216\u6cf0\u745e\u6c99\u7684\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u4e00\u4e9b\u7f55\u89c1\u7684\u526f\u4f5c\u7528\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u90e8\u95ee\u9898\uff1a\u6cf0\u745e\u6c99\uff08Tagrisso\uff09\u5728\u6781\u5c11\u6570\u60c5\u51b5\u4e0b\u53ef\u80fd\u5f15\u8d77\u773c\u90e8\u95ee\u9898\uff0c\u4f8b\u5982\u6e83\u75a1\u3002\u5982\u679c\u60a8\u53d1\u73b0\u4ee5\u4e0b\u773c\u90e8\u95ee\u9898\uff0c\u8bf7\u9884\u7ea6\u5c31\u533b\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u75db<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u775b\u56e0\u523a\u6fc0\u800c\u6d41\u6cea<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u773c\u775b\u80bf\u80c0\u6216\u53d1\u7ea2<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u89c6\u529b\u6a21\u7cca<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5bf9\u5149\u654f\u611f<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5fc3\u529b\u8870\u7aed\uff1a\u670d\u7528\u6cf0\u745e\u6c99\uff08Tagrisso\uff09\u53ef\u80fd\u4f1a\u589e\u52a0\u5fc3\u529b\u8870\u7aed\u7684\u98ce\u9669\u3002\u5982\u679c\u60a8\u51fa\u73b0\u4ee5\u4e0b\u5fc3\u529b\u8870\u7aed\u75c7\u72b6\uff0c\u8bf7\u7acb\u5373\u8054\u7cfb\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\uff1a<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5f02\u5e38\u6216\u6301\u7eed\u7684\u75b2\u52b3<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u547c\u5438\u6025\u4fc3\u6216\u547c\u5438\u56f0\u96be\uff0c\u5c24\u5176\u662f\u5728\u8eba\u4e0b\u65f6<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u811a\u3001\u8e1d\u6216\u817f\u80bf\u80c0<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5feb\u901f\u589e\u91cd<\/p>\n<\/li>\n<\/ul>\n<h2>\u5982\u4f55\u50a8\u5b58\u5965\u5e0c\u66ff\u5c3c\uff1f<\/h2>\n<p>\u5965\u5e0c\u66ff\u5c3c\u5e94\u50a8\u5b58\u5728\u5ba4\u6e29 20\u00b0C \u81f3 25\u00b0C\uff0868\u00b0F \u81f3 77\u00b0F\uff09\u7684\u5bc6\u95ed\u5bb9\u5668\u4e2d\u3002\u52a1\u5fc5\u907f\u514d\u836f\u7269\u53d7\u70ed\u3001\u53d7\u6f6e\u548c\u9633\u5149\u76f4\u5c04\u3002\u6b64\u5916\uff0c\u8bf7\u52ff\u51b7\u51bb\uff0c\u5e76\u5c06\u836f\u7269\u653e\u5728\u513f\u7ae5\u548c\u5ba0\u7269\u63a5\u89e6\u4e0d\u5230\u7684\u5730\u65b9\u3002\u5982\u679c\u836f\u7269\u5df2\u8fc7\u671f\uff0c\u8bf7\u4e22\u5f03\u4efb\u4f55\u672a\u4f7f\u7528\u7684\u836f\u7269\u3002<\/p>\n<h2>\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u524d\u9700\u6ce8\u610f\u7684\u7279\u6b8a\u4e8b\u9879<\/h2>\n<p>\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u524d\uff0c\u60a8\u9700\u8981\u9075\u5faa\u4ee5\u4e0b\u6ce8\u610f\u4e8b\u9879\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5982\u679c\u60a8\u5bf9\u5965\u5e0c\u66ff\u5c3c\u8fc7\u654f\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u3002<\/p>\n<\/li>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u8bf7\u544a\u77e5\u533b\u751f\u60a8\u6b63\u5728\u670d\u7528\u7684\u5904\u65b9\u836f\u548c\u975e\u5904\u65b9\u836f\u3002\u6b64\u5916\uff0c\u8fd8\u8981\u544a\u77e5\u60a8\u6b63\u5728\u670d\u7528\u7684\u7ef4\u751f\u7d20\u3001\u8425\u517b\u8865\u5145\u5242\u548c\u8349\u836f\u4ea7\u54c1\u7684\u540d\u79f0\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u5982\u679c\u60a8\u6709\u6216\u66fe\u7ecf\u6709\u4ee5\u4e0b\u75c7\u72b6\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\uff1a<\/p>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\"> QT \u7efc\u5408\u5f81\uff0c\u5fc3\u5f8b\u4e0d\u9f50\uff1b\u9ad8\u8840\u538b\uff1b\u5fc3\u529b\u8870\u7aed\uff1b\u8840\u6db2\u4e2d\u94a0\u3001\u94be\u3001\u9499\u6216\u9541\u542b\u91cf\u5931\u8861\uff1b\u4e25\u91cd\u7684\u773c\u90e8\u75be\u75c5\uff1b\u80ba\u529f\u80fd\u969c\u788d\u3001\u80ba\u764c\uff1b\u6216\u80be\u810f\u75be\u75c5\u3002<\/p>\n<\/li>\n<\/ul>\n<ul>\n<li dir=\"ltr\">\n<p dir=\"ltr\" role=\"presentation\">\u5982\u679c\u60a8\u662f\u5a74\u5e7c\u513f\u7684\u6bcd\u4eb2\uff0c\u8bf7\u544a\u77e5\u60a8\u7684\u533b\u751f\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u533b\u751f\u53ef\u80fd\u4f1a\u5efa\u8bae\u60a8\u5728\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u671f\u95f4\u4e0d\u8981\u54fa\u4e73\uff0c\u5e76\u5728\u6700\u540e\u4e00\u6b21\u670d\u836f\u540e\u4e24\u5468\u5185\u907f\u514d\u54fa\u4e73\u3002<\/p>\n<\/li>\n<\/ul>\n<p>\u4e86\u89e3\u60c5\u51b5\u540e\uff0c\u60a8\u7684\u533b\u751f\u53ef\u80fd\u4f1a\u8c03\u6574\u60a8\u7684\u836f\u7269\u5242\u91cf\uff0c\u6216\u8005\u8981\u6c42\u60a8\u76d1\u6d4b\u5965\u5e0c\u66ff\u5c3c\u7684\u526f\u4f5c\u7528\u3002<\/p>\n<h2>\u5965\u5e0c\u66ff\u5c3c\u4e0e\u5176\u4ed6\u836f\u7269\u7684\u76f8\u4e92\u4f5c\u7528\u3002<\/h2>\n<p>\u4ee5\u4e0b\u8868\u683c\u5217\u51fa\u4e86\u53ef\u80fd\u4e0e\u5965\u5e0c\u66ff\u5c3c\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\u7684\u836f\u7269\u3002\u867d\u7136\u6b64\u8868\u5e76\u672a\u5305\u542b\u6240\u6709\u53ef\u80fd\u4e0e\u6cf0\u745e\u6c99\uff08Tagrisso\uff09\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\u7684\u836f\u7269\uff0c\u4f46\u53ef\u4ee5\u5e2e\u52a9\u60a8\u4e86\u89e3\u6f5c\u5728\u7684\u98ce\u9669\uff1a <\/p>\n<table dir=\"ltr\" style=\"height: 1542px\" border=\"1\" width=\"1379\" cellspacing=\"0\" cellpadding=\"0\" data-sheets-root=\"1\" data-sheets-baot=\"1\">\n<colgroup>\n<col width=\"100\">\n<col width=\"100\">\n<col width=\"675\"><\/colgroup>\n<tbody>\n<tr>\n<td>\u533b\u5b66\u8bfe<\/td>\n<td>\u533b\u5b66\u5b9e\u4f8b<\/td>\n<td>\u4e0e\u5965\u5e0c\u66ff\u5c3c\u7684\u76f8\u4e92\u4f5c\u7528\u7ed3\u679c<\/td>\n<\/tr>\n<tr>\n<td>\u7279\u5b9a\u6297\u7cbe\u795e\u75c5\u836f\u7269<\/td>\n<td>\u6c2f\u6c2e\u5e73\uff08Clozaril\uff09<\/p>\n<p>\u963f\u7acb\u54cc\u5511\uff08\u5b89\u7acb\u798f\uff09<\/p>\n<p>\u55b9\u786b\u5e73\uff08\u601d\u745e\u5eb7\uff09<\/td>\n<td>\u5b83\u53ef\u80fd\u5bfc\u81f4\u957fQT\u95f4\u671f\u7efc\u5408\u5f81\uff0c\u4e00\u79cd\u5f02\u5e38\u7684\u5fc3\u5f8b\uff0c\u8fdb\u800c\u5f15\u53d1\u4e25\u91cd\u7684\u5fc3\u810f\u95ee\u9898\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u7279\u5b9a\u7684\u6b62\u5410\u836f\u7269<\/td>\n<td>\u6602\u4e39\u53f8\u743c\uff08\u4f50\u592b\u5170\uff09<\/p>\n<p>\u591a\u62c9\u53f8\u743c\uff08\u5b89\u6cfd\u7f8e\uff09<\/td>\n<td>\u53ef\u80fd\u5bfc\u81f4\u957fQT\u95f4\u671f\u7efc\u5408\u5f81\uff0c\u589e\u52a0\u5fc3\u5f8b\u5931\u5e38\u7684\u98ce\u9669\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u67d0\u4e9b\u827e\u6ecb\u75c5\u836f\u7269<\/td>\n<td>\u4f9d\u975e\u97e6\u4f26<\/p>\n<p>\u5229\u5339\u97e6\u6797\uff08Edurant\uff09<\/p>\n<p>\u591a\u66ff\u62c9\u97e6\uff08Tivicay\uff09<\/td>\n<td>\u53ef\u80fd\u589e\u52a0 HIV \u836f\u7269\u526f\u4f5c\u7528\u7684\u98ce\u9669\uff0c\u5305\u62ec\u53d1\u751f\u957f QT \u7efc\u5408\u5f81\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u67d0\u4e9b\u6297\u751f\u7d20<\/td>\n<td>\u83ab\u897f\u6c99\u661f\uff08Avelox\uff09<\/p>\n<p>\u514b\u62c9\u9709\u7d20<\/p>\n<p>\u963f\u5947\u9709\u7d20\uff08\u5e0c\u8212\u7f8e\uff09<\/td>\n<td>\u53ef\u80fd\u5bfc\u81f4\u5fc3\u5f8b\u5931\u5e38\u6216\u52a0\u91cd\u5df2\u6709\u7684\u5fc3\u810f\u95ee\u9898\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u67d0\u4e9b\u6297\u6291\u90c1\u836f<\/td>\n<td>\u827e\u53f8\u897f\u915e\u666e\u5170\uff08Lexapro\uff09<\/p>\n<p>\u897f\u915e\u666e\u5170\uff08Celexa\uff09<\/p>\n<p>\u6c2f\u7c73\u5e15\u660e\uff08Anafranil\uff09<\/td>\n<td>\u53ef\u5bfc\u81f4\u957fQT\u95f4\u671f\u7efc\u5408\u5f81\uff0c\u8fdb\u800c\u5f15\u8d77\u5fc3\u5f8b\u5931\u5e38\u548c\u6f5c\u5728\u7684\u5fc3\u810f\u98ce\u9669\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u6297\u5fc3\u5f8b\u5931\u5e38\u836f<\/td>\n<td>\u80fa\u7898\u916e\uff08Pacerone\uff09<\/p>\n<p>\u7d22\u4ed6\u6d1b\u5c14\uff08\u500d\u4ed6\u6d1b\u5c14\u3001\u7d22\u6797\uff09<\/p>\n<p>\u4e19\u5421\u80fa\uff08Norpace\uff09<\/td>\n<td>\u53ef\u5f15\u8d77\u6216\u52a0\u91cd\u957fQT\u7efc\u5408\u5f81\uff0c\u8fdb\u800c\u5bfc\u81f4\u5371\u53ca\u751f\u547d\u7684\u5fc3\u5f8b\u5931\u5e38\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u6297\u7ed3\u6838\u836f\u7269<\/td>\n<td>\u5229\u798f\u5e73<\/p>\n<p>\u91cc\u6cd5\u4e01<\/p>\n<p>\u5229\u9a6c\u5766<\/td>\n<td>\u5b83\u53ef\u4ee5\u901a\u8fc7\u589e\u52a0\u5965\u5e0c\u66ff\u5c3c\u7684\u4ee3\u8c22\u548c\u964d\u4f4e\u5176\u8840\u6d46\u6d53\u5ea6\u6765\u964d\u4f4e\u5965\u5e0c\u66ff\u5c3c\u7684\u7597\u6548\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u80c6\u56fa\u9187\u836f\u7269<\/td>\n<td>\u745e\u8212\u4f10\u4ed6\u6c40<\/td>\n<td>\u53ef\u80fd\u4f1a\u589e\u52a0\u745e\u8212\u4f10\u4ed6\u6c40\u526f\u4f5c\u7528\u7684\u98ce\u9669\uff0c\u4f8b\u5982\u808c\u8089\u95ee\u9898\u6216\u809d\u635f\u4f24\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u6b62\u6cfb\u836f<\/td>\n<td>\u6d1b\u54cc\u4e01\u80fa<\/td>\n<td>\u53ef\u80fd\u4f1a\u589e\u52a0\u6d1b\u54cc\u4e01\u80fa\u526f\u4f5c\u7528\u7684\u98ce\u9669\uff0c\u4f8b\u5982\u5fc3\u5f8b\u5931\u5e38\u6216\u4fbf\u79d8\u3002<\/td>\n<\/tr>\n<tr>\n<td>\u7279\u6548\u6297\u766b\u75eb\u836f\u7269<\/td>\n<td>\u5361\u9a6c\u897f\u5e73\uff08Tegretol \u7b49\uff09<\/p>\n<p>\u82ef\u59a5\u82f1\u94a0\uff08Dilantin\uff09<\/p>\n<p>\u82ef\u5df4\u6bd4\u59a5<\/td>\n<td>\u53ef\u80fd\u4f1a\u964d\u4f4e\u5965\u5e0c\u66ff\u5c3c\u7684\u7597\u6548\uff0c\u4f7f\u5176\u5728\u6cbb\u7597\u764c\u75c7\u65b9\u9762\u6548\u679c\u964d\u4f4e\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h2 dir=\"ltr\">\u7ed3\u8bba<\/h2>\n<p dir=\"ltr\">\u5965\u5e0c\u66ff\u5c3c\u662f\u80ba\u764c\u6cbb\u7597\u9886\u57df\u7684\u4e00\u9879\u7a81\u7834\u6027\u53d1\u660e\uff0c\u4f46\u5b83\u4e5f\u5b58\u5728\u4e00\u4e9b\u98ce\u9669\u3002\u7136\u800c\uff0c\u4e0e\u6240\u6709\u5f3a\u6548\u836f\u7269\u4e00\u6837\uff0c\u5b83\u4e5f\u4f1a\u5e26\u6765\u8f7b\u5fae\u548c\u66f4\u4e25\u91cd\u7684\u6f5c\u5728\u526f\u4f5c\u7528\u3002<\/p>\n<p dir=\"ltr\">\u5965\u5e0c\u66ff\u5c3c\u7684\u4e00\u4e9b\u526f\u4f5c\u7528\u53ef\u80fd\u662f\u6682\u65f6\u7684\u4e14\u53ef\u63a7\u7684\uff0c\u4f46\u53e6\u4e00\u4e9b\u526f\u4f5c\u7528\u2014\u2014\u867d\u7136\u7f55\u89c1\u2014\u2014\u53ef\u80fd\u5f88\u4e25\u91cd\uff0c\u4f1a\u5f71\u54cd\u91cd\u8981\u5668\u5b98\u5e76\u5bfc\u81f4\u957f\u671f\u5065\u5eb7\u5e76\u53d1\u75c7\u3002\u4e86\u89e3\u8fd9\u4e9b\u526f\u4f5c\u7528\u5bf9\u4e8e\u5b89\u5168\u6cbb\u7597\u81f3\u5173\u91cd\u8981\u3002<\/p>\n<p dir=\"ltr\">\u60f3\u4ee5\u4f18\u60e0\u7684\u4ef7\u683c\u4e70\u5230\u53ef\u9760\u7684\u836f\u54c1\u5417\uff1f\u7acb\u5373\u8bbf\u95ee Indogenmed\u2014\u2014\u60a8\u503c\u5f97\u4fe1\u8d56\u7684\u5728\u7ebf\u836f\u623f\uff0c\u4e3a\u60a8\u63d0\u4f9b\u5feb\u901f\u3001\u5b89\u5168\u3001\u4fbf\u6377\u7684\u5904\u65b9\u836f\u9001\u8d27\u4e0a\u95e8\u670d\u52a1\u3002<\/p>\n<p dir=\"ltr\">\u7acb\u5373\u8d2d\u4e70\uff0c\u81ea\u4fe1\u638c\u63a7\u60a8\u7684\u5065\u5eb7\uff01<\/p>\n<h2 dir=\"ltr\">\u5e38\u89c1\u95ee\u9898\u89e3\u7b54<\/h2>\n<ol>\n<li dir=\"ltr\">\n<h3>\u836f\u7269\u6700\u4e25\u91cd\u7684\u526f\u4f5c\u7528\u4e4b\u4e00\u662f\u4ec0\u4e48\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u6cf0\u745e\u6c99\uff08Tagrisso\uff09\u6709\u51e0\u79cd\u4e25\u91cd\u7684\u526f\u4f5c\u7528\uff0c\u5305\u62ec\u4e25\u91cd\u7684\u8fc7\u654f\u53cd\u5e94\u3001\u5fc3\u5f8b\u5931\u5e38\u3001\u5fc3\u810f\u9aa4\u505c\u3001\u4e25\u91cd\u7684\u773c\u90e8\u95ee\u9898\u3001\u4e25\u91cd\u7684\u76ae\u80a4\u53cd\u5e94\u3001\u80ba\u90e8\u708e\u75c7\u548c\u8840\u6db2\u75be\u75c5\u3002<\/p>\n<ol start=\"2\">\n<li dir=\"ltr\">\n<h3>\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u671f\u95f4\u5e94\u907f\u514d\u98df\u7528\u54ea\u4e9b\u98df\u7269\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u8461\u8404\u67da\u548c\u8461\u8404\u67da\u6c41\u4f1a\u5e72\u6270\u5965\u5e0c\u66ff\u5c3c\u7684\u836f\u6548\uff0c\u5f71\u54cd\u5176\u8840\u6db2\u6d53\u5ea6\uff0c\u4ece\u800c\u53ef\u80fd\u964d\u4f4e\u7597\u6548\u6216\u589e\u52a0\u526f\u4f5c\u7528\u3002\u56e0\u6b64\uff0c\u6cbb\u7597\u671f\u95f4\u52a1\u5fc5\u907f\u514d\u98df\u7528\u8461\u8404\u67da\u548c\u8461\u8404\u67da\u6c41\u3002<\/p>\n<ol start=\"3\">\n<li dir=\"ltr\">\n<h3>\u6cf0\u745e\u6c99\u7684\u526f\u4f5c\u7528\u4f1a\u6d88\u5931\u5417\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u670d\u7528\u6cf0\u745e\u6c99\u53ef\u80fd\u4f1a\u5f15\u8d77\u591a\u79cd\u526f\u4f5c\u7528\uff0c\u6709\u4e9b\u526f\u4f5c\u7528\u6bd4\u8f83\u5e38\u89c1\uff0c\u6709\u4e9b\u5219\u8f83\u4e3a\u7f55\u89c1\u3002\u8fd9\u4e9b\u526f\u4f5c\u7528\u53ef\u80fd\u4f1a\u6301\u7eed\u6570\u5929\u6216\u6570\u5468\u3002\u7136\u800c\uff0c\u4e5f\u5b58\u5728\u4e00\u4e9b\u4e25\u91cd\u4e14\u7f55\u89c1\u7684\u98ce\u9669\uff0c\u9700\u8981\u54a8\u8be2\u5408\u683c\u7684\u533b\u751f\u3002<\/p>\n<ol start=\"4\">\n<li dir=\"ltr\">\n<h3>\u54ea\u91cc\u53ef\u4ee5\u4e70\u5230\u5965\u5e0c\u66ff\u5c3c\u836f\u7269\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u8d2d\u4e70\u5965\u5e0c\u66ff\u5c3c\u836f\u7269\u65f6\uff0c\u8bf7\u52a1\u5fc5\u9009\u62e9\u50cfIndogenmed\u8fd9\u6837\u503c\u5f97\u4fe1\u8d56\u7684\u6e20\u9053\u3002\u6211\u4eec\u63d0\u4f9b\u4f18\u8d28\u3001\u7ecf\u533b\u751f\u8ba4\u53ef\u7684\u836f\u7269\uff0c\u5e76\u9001\u8d27\u4e0a\u95e8\u3002\u6211\u4eec\u7684\u76ee\u6807\u662f\u4e3a\u5168\u7403\u6700\u4e25\u91cd\u7684\u75be\u75c5\u63d0\u4f9b\u53ef\u6301\u7eed\u4e14\u7ecf\u6d4e\u6709\u6548\u7684\u836f\u7269\u3002<\/p>\n<ol start=\"5\">\n<li dir=\"ltr\">\n<h3> Tagrisso \u4e0e\u75ab\u82d7\u4e4b\u95f4\u662f\u5426\u5b58\u5728\u76f8\u4e92\u4f5c\u7528\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u533b\u5b66\u7814\u7a76\u8868\u660e\uff0c\u5965\u5e0c\u66ff\u5c3c\u4e0e\u75ab\u82d7\u4e4b\u95f4\u6ca1\u6709\u5df2\u77e5\u7684\u76f8\u4e92\u4f5c\u7528\u3002\u4f46\u662f\uff0c\u5982\u679c\u60a8\u5373\u5c06\u63a5\u79cd\u6216\u8fd1\u671f\u63a5\u79cd\u8fc7\u4efb\u4f55\u75ab\u82d7\uff0c\u8bf7\u52a1\u5fc5\u544a\u77e5\u60a8\u7684\u533b\u751f\u6216\u836f\u5242\u5e08\u3002<\/p>\n<ol start=\"6\">\n<li dir=\"ltr\">\n<h3>\u5982\u679c\u6211\u6f0f\u670d\u4e86\u4e00\u6b21\u5965\u5e0c\u66ff\u5c3c\u600e\u4e48\u529e\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u5982\u679c\u60a8\u5fd8\u8bb0\u670d\u836f\uff0c\u53ea\u9700\u8df3\u8fc7\u8be5\u5242\u5373\u53ef\u3002\u8bf7\u5728\u9884\u5b9a\u65f6\u95f4\u670d\u7528\u4e0b\u4e00\u5242\u5965\u5e0c\u66ff\u5c3c\u3002\u5207\u52ff\u4e3a\u4e86\u5f25\u8865\u6f0f\u670d\u7684\u5242\u91cf\u800c\u670d\u7528\u989d\u5916\u5242\u91cf\u6216\u540c\u65f6\u670d\u7528\u4e24\u5242\u3002<\/p>\n<ol start=\"7\">\n<li dir=\"ltr\">\n<h3>\u5965\u5e0c\u66ff\u5c3c\u6cbb\u7597\u7684\u63a8\u8350\u7597\u7a0b\u662f\u591a\u4e45\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u6839\u636e NCCN \u6307\u5357\uff0c\u5965\u5e0c\u66ff\u5c3c\uff08\u6cf0\u745e\u6c99\uff09\u901a\u5e38\u63a8\u8350\u7528\u4e8e\u5b8c\u5168\u5207\u9664\u7684 IB-IIIA \u671f\u6216 IIIB \u671f\uff08T3\uff0cN2\uff09EGFR \u7a81\u53d8\uff0819 \u53f7\u5916\u663e\u5b50\u7f3a\u5931\uff0c21 \u53f7\u5916\u663e\u5b50 L858R \u7a81\u53d8\uff09\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u7684\u8f85\u52a9\u6cbb\u7597\uff0c\u7597\u7a0b\u4e3a 3 \u5e74\u3002<\/p>\n<ol start=\"8\">\n<li dir=\"ltr\">\n<h3>\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u53ef\u80fd\u5b58\u5728\u54ea\u4e9b\u5fc3\u810f\u98ce\u9669\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u867d\u7136\u7f55\u89c1\uff0c\u4f46\u5965\u5e0c\u66ff\u5c3c\u4e0e\u5fc3\u810f\u6bd2\u6027\u6709\u5173\uff0c\u5305\u62ec\u5fc3\u529b\u8870\u7aed\u3001QT\u95f4\u671f\u5ef6\u957f\u548c\u5fc3\u623f\u98a4\u52a8\u7b49\u75be\u75c5\uff0c\u5c24\u5176\u662f\u5728\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u4e2d\u3002<\/p>\n<ol start=\"9\">\n<li dir=\"ltr\">\n<h3>\u6211\u53ef\u4ee5\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u591a\u4e45\uff1f<\/h3>\n<\/li>\n<\/ol>\n<p dir=\"ltr\">\u5965\u5e0c\u66ff\u5c3c\u7684\u6cbb\u7597\u6301\u7eed\u65f6\u95f4\u53d6\u51b3\u4e8e\u836f\u7269\u7597\u6548\u548c\u60a3\u8005\u5bf9\u526f\u4f5c\u7528\u7684\u8010\u53d7\u7a0b\u5ea6\u3002\u901a\u5e38\u60c5\u51b5\u4e0b\uff0c\u53ea\u8981\u836f\u7269\u6709\u6548\u4e14\u526f\u4f5c\u7528\u53ef\u63a7\uff0c\u60a8\u5c31\u9700\u8981\u7ee7\u7eed\u6cbb\u7597\uff0c\u533b\u751f\u4f1a\u5b9a\u671f\u76d1\u6d4b\u60a8\u7684\u6cbb\u7597\u8fdb\u5c55\u3002<\/p>\n<p dir=\"ltr\"><b>\u514d\u8d23\u58f0\u660e<\/b>\uff1a\u670d\u7528\u5965\u5e0c\u66ff\u5c3c\u7247\u524d\uff0c\u8bf7\u52a1\u5fc5\u54a8\u8be2\u5408\u683c\u7684\u533b\u7597\u4fdd\u5065\u4e13\u4e1a\u4eba\u5458\uff0c\u4ee5\u786e\u4fdd\u5176\u5b89\u5168\u6027\u548c\u9002\u5408\u60a8\u7684\u5065\u5eb7\u9700\u6c42\u3002<\/p>\n<h2>\u53c2\u8003\uff1a<\/h2>\n<p dir=\"ltr\"> <a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements\/osimertinib-oral-route\/description\/drg-20165188\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.mayoclinic.org\/drugs-supplements\/osimertinib-oral-route\/description\/drg-20165188<\/a><\/p>\n<p dir=\"ltr\"> <a href=\"https:\/\/my.clevelandclinic.org\/health\/drugs\/19333-osimertinib-tablets\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/my.clevelandclinic.org\/health\/drugs\/19333-osimertinib-tablets<\/a><\/p>\n<p dir=\"ltr\"> <a href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-170434\/tagrisso-oral\/details\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.webmd.com\/drugs\/2\/drug-170434\/tagrisso-oral\/details<\/a><\/p>\n<p dir=\"ltr\"> <a href=\"https:\/\/www.cancerresearchuk.org\/about-cancer\/treatment\/drugs\/osimertinib\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.cancerresearchuk.org\/about-cancer\/treatment\/drugs\/osimertinib<\/a><\/p>\n<p dir=\"ltr\"> <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/drugs-tagrisso-interactions#tagrisso-and-other-medications\" target=\"_blank\" rel=\"noopener nofollow\">https:\/\/www.medicalnewstoday.com\/articles\/drugs-tagrisso-interactions#tagrisso-and-other-medications<\/a> <a href=\"https:\/\/www.medicalnewstoday.com\/articles\/drugs-tagrisso-interactions#tagrisso-and-other-medications\" target=\"_blank\" rel=\"noopener nofollow\">\u00a0<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u533b\u751f\u901a\u5e38\u4f1a\u5f00\u5177\u5965\u5e0c\u66ff\u5c3c\u6765\u6cbb\u7597\u4e0e\u7279\u5b9a EGFR\uff08\u8868\u76ae\u751f\u957f\u56e0\u5b50\u53d7\u4f53\uff09\u7a81\u53d8\u76f8\u5173\u7684\u80ba\u764c\u3002\u7136\u800c\uff0c\u5b83\u7684\u5f71\u54cd\u8fdc\u4e0d\u6b62\u4e8e\u6b64\u3002\u867d\u7136 [&hellip;]<\/p>\n","protected":false},"author":124,"featured_media":137034,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2895],"tags":[],"class_list":["post-39442","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer-medicine"],"_links":{"self":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts\/39442","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/users\/124"}],"replies":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/comments?post=39442"}],"version-history":[{"count":0,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/posts\/39442\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/media\/137034"}],"wp:attachment":[{"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/media?parent=39442"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/categories?post=39442"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/indogenmed.org\/zh-hans\/wp-json\/wp\/v2\/tags?post=39442"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}