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| Brand Name | Alkacel 2 |
| Packaging Type | Bottle |
| Molecule | Melphalan |
| Generic Name | Melphalan 2mg |
| Manufactured By | Celon Laboratories |
| Quantity | 25 Tablets |
| Form | Tablet |
| Country of Origin | India |
| Categories | Oncology |
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Delivery in 10 to 15 Business Days*
Introduction to Alkacel Melphalan 2mg Tablet
Alkacel melphalan 2mg Tablet is a chemotherapy medicine used on prescription. It is mainly used for the treatment of specific cancers which include ovarian cancer, and multiple myeloma. Celon Laboratories is known for manufacturing this medication. Melphalan is a member of a class of drugs called alkylating agents.
Melphalan is the active ingredient of Alkacel melphalan. Melphalan works by altering the DNA of the cancerous cells such that they are not able to reproduce or spread. The medication can be found in formulations of 2mg and 5mg tablets among other strengths. That gives medical practitioners more freedom in dosing since they can adjust the dosage form according to the needs of each patient and their condition.
Alkacel Melphalan is an important component in the treatment plans of patients suffering from cancer. It has been effective in the management of cancer and other less common conditions. For its effectiveness, safety, and predominately wide use, it is often prescribed by oncologists. The substance is taken on an empty stomach once a day to increase its absorption rate. It is most often used alongside other medications to increase its effectiveness against cancer.
How Alkacel Melphalan 2mg Tablet Works
Melphalan, the active ingredient in Melphalan 2mg Tablets, is a chemotherapy drug. It belongs to the class of alkylating agents. These agents target the DNA of rapidly dividing cancer cells.
Melphalan works by attaching an alkyl group to the DNA strands in cancer cells. This chemical alteration disrupts the structure and function of the DNA. It prevents the cells from replicating properly.
Without the ability to duplicate their DNA, cancer cells cannot divide. As a result, these cells are unable to multiply and eventually die.
This mechanism makes Melphalan effective against fast-growing cancers. These include multiple myeloma and ovarian cancer. By damaging the DNA of cancer cells, Melphalan halts their growth. It also helps reduce the size and spread of tumors.
Unlike some other treatments, Melphalan targets cancer cells that divide quickly. While it can affect some normal cells, its precision helps minimize damage to healthy tissue.Melphalan is often used in combination therapy to enhance its effectiveness. In some cases, it is used before stem cell transplantation. This prepares the body for further treatment.
Uses of Alkacel Melphalan 2mg Tablet
Alkacel Melphalan 2mg Tablets are a chemotherapy medication widely used for treating certain cancers. Its primary uses include:
- Alkacel Melphalan is a standard treatment for multiple myeloma. This is a type of blood cancer that affects plasma cells in the bone marrow.
- The medication is also used to treat ovarian cancer. It is particularly helpful when other treatments have not been successful.
- Alkacel Melphalan is often given in high doses before stem cell or bone marrow transplantation.
- In some cases, it is used to treat rare cancers or conditions involving abnormal cell growth. This is determined by a healthcare provider.
- It is frequently combined with other chemotherapy drugs. This enhances its effectiveness in fighting cancer.
Dosage of Alkacel Melphalan 2mg Tablet
The dosage of Alkacel Melphalan 2mg Tablet is tailored to each patient's specific medical needs and condition. It is typically taken as a daily dose on an empty stomach to ensure the best possible medication absorption.
Usual Dosage:
- Starting Dose: The initial dosage is usually 2mg taken once daily. The doctor may adjust the dosage depending on the patient's response and the type of cancer.
- Administration: The tablet should be taken orally with a full glass of water. Do not crush, chew, or break the tablet. If you miss a dose, take it as soon as you remember, but skip the missed dose if it's almost time for the next one. Do not double up on doses.
Your doctor will monitor your progress and adjust the treatment plan as needed. It is crucial to follow the prescribed dosage and not make any changes without consulting your healthcare provider.
Side Effects of Alkacel Melphalan 2mg Tablet
Common Side Effects:
- Increased Risk of Infection
- Breathlessness and Pale Appearance
- Bruising and Bleeding
- Nausea and Vomiting
- Tingling or Warm Feeling in the Vein
- Diarrhea
- Mouth Sores and Ulcers.
- Hair Loss
- Muscle Problems
- Less Common Side Effects:
- Kidney Issues
- Liver Changes
- Blood Disorders
- Skin Rash or Itchiness
- Lung Issues
- Allergic Reactions
Rare Side Effects:
- Second Cancers: Such as acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
- Blood Clots: Symptoms include pain, redness, or swelling at the clot site and shortness of breath.
- Amenorrhoea: Women may experience a stop in menstrual periods.
Precautions
Before starting treatment with Alkacel Melphalan, discuss your full medical history with your doctor. Some important factors to consider include:
Allergic ReactionsInform your doctor if you have any known allergies to Melphalan or other ingredients in the tablet.
Pregnancy and BreastfeedingMelphalan can harm a developing fetus, so it should not be taken during pregnancy. Women should avoid pregnancy during treatment and for a certain period afterward. Discuss contraception options with your doctor. Melphalan can also pass into breast milk, so breastfeeding should be avoided during treatment.
Kidney FunctionAlkacel Melphalan may affect kidney function. If you have kidney disease or have had recent kidney issues, your doctor may adjust your dosage or monitor your kidney function more closely.
Bone Marrow SuppressionMelphalan may cause bone marrow suppression, leading to low blood cell counts. Regular blood tests are required to monitor your red blood cell, white blood cell, and platelet levels during treatment.
Vaccinations
Avoid live vaccines while taking Melphalan, as the drug may suppress your immune system, making vaccinations less effective.
Storage and Disposal of Alkacel Melphalan 2mg Tablet
Proper storage and disposal are critical for maintaining the effectiveness and safety of Alkacel Melphalan:
Storage: Store the medication in its original packaging, tightly closed, and away from moisture and heat. Keep the medication in a cool, dry place, preferably in the refrigerator, and out of reach of children.
Disposal: Do not dispose of this medication by flushing it down the toilet or throwing it in the trash. Contact your pharmacist or local waste disposal service for guidance on safe disposal methods.
Compare Generic Vs branded
| Category | Alkacel | Alkeran |
| Active Ingredients | Melphalan | Melphalan |
| Manufacturer | Celon Laboratories | Glaxo Smithe Kline Group |
| Primary Use | Multiple myeloma, Ovarian Cancer, and a rare cancers | Multiple Myeloma, Ovarian Cancer |
| Key Difference | Generic Version, Offers Cost-effective treatment | Branded Version, Higher cost |
| Potential Side Effect | Nausea, vomiting, low blood counts | Nausea, fatigue, mouth sores |
| Cost | $140 (50 tablet) | $605 (50 tablet) |
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