Alkacel 2 mg Tablets

Alkacel 2 mg Tablets is a prescription chemotherapy medicine primarily used for the treatment of certain cancers, including multiple myeloma and ovarian cancer. It is manufactured by Celon Laboratories and contains Melphalan as its active ingredient.

Melphalan belongs to a class of anticancer drugs known as alkylating agents. It works by altering the DNA of cancer cells, preventing them from reproducing and spreading further. Alkacel Melphalan is available in different strengths, including 2 mg and 5 mg tablets, allowing doctors to adjust the dosage according to individual patient needs and disease severity.

Due to its effectiveness and wide clinical use, Alkacel Melphalan is an important component of many cancer treatment protocols and is often prescribed by oncologists. The tablet is usually taken once daily on an empty stomach to improve absorption and is commonly used in combination with other anticancer medicines to enhance treatment outcomes.

How Alkacel 2 mg Tablets Works

Melphalan, the active ingredient in Alkacel Melphalan, is a chemotherapy drug from the alkylating agent class. It targets rapidly dividing cancer cells by attaching an alkyl group to their DNA strands.

This chemical alteration disrupts DNA structure and function, preventing cancer cells from replicating properly. As a result, these cells are unable to divide, leading to cell death. This mechanism makes Melphalan particularly effective against fast-growing cancers such as multiple myeloma and ovarian cancer.

By damaging the DNA of cancer cells, Alkacel Melphalan helps slow tumor growth and reduce cancer spread. It is often used as part of combination therapy and may also be administered before stem cell or bone marrow transplantation to prepare the body for further treatment.

Uses of Alkacel Melphalan 2 mg Tablet

Alkacel Melphalan 2 mg Tablet is widely used for the treatment of certain cancers, including:

• Multiple myeloma, a type of blood cancer affecting plasma cells
• Ovarian cancer, especially when other treatments have not been effective
• High-dose therapy before stem cell or bone marrow transplantation
• Treatment of rare cancers or abnormal cell growth conditions, as determined by a healthcare provider
• Combination chemotherapy regimens to improve overall treatment effectiveness

Dosage of Alkacel Melphalan 2 mg Tablet

The dosage of Alkacel Melphalan 2 mg Tablet is individualized based on the patient’s condition, cancer type, and response to treatment.

Usual Dosage Guidelines

• Starting dose: Typically 2 mg once daily
• Administration: Take the tablet orally with a full glass of water
• Food: Take on an empty stomach for better absorption
• Do not crush, chew, or break the tablet
• If a dose is missed, take it as soon as remembered, unless it is close to the next dose
• Do not double the dose

Your doctor will monitor your progress regularly and adjust the dosage if required. Always follow medical advice strictly.

Side Effects of Alkacel Melphalan 2 mg Tablet

Common Side Effects

• Increased risk of infection
• Breathlessness and pale appearance
• Bruising and bleeding
• Nausea and vomiting
• Tingling or warm sensation in the veins
• Diarrhea
• Mouth sores or ulcers
• Hair loss
• Muscle problems

Less Common Side Effects

• Kidney problems
• Liver function changes
• Blood disorders
• Skin rash or itching
• Lung-related issues
• Allergic reactions

Rare Side Effects

• Secondary cancers such as acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
• Blood clots, causing pain, swelling, redness, or shortness of breath
• Amenorrhoea, where menstrual periods may stop in women

Precautions

Before starting Alkacel Melphalan, inform your doctor about your complete medical history. Important precautions include:

Allergic Reactions

Inform your doctor if you are allergic to Melphalan or any other ingredients.

Pregnancy and Breastfeeding

Melphalan can harm an unborn baby. Avoid pregnancy during treatment and for a recommended period afterward. Breastfeeding should also be avoided, as the drug may pass into breast milk.

Kidney Function

Patients with kidney disease may require dose adjustments and closer monitoring.

Bone Marrow Suppression

Alkacel Melphalan can lower blood cell counts. Regular blood tests are necessary to monitor red blood cells, white blood cells, and platelets.

Vaccinations

Avoid live vaccines during treatment, as the immune system may be suppressed.

Storage and Disposal of Alkacel Melphalan 2 mg Tablet

Storage

• Store in original packaging, tightly closed
• Keep away from moisture and heat
• Store in a cool, dry place, preferably in a refrigerator
• Keep out of reach of children

Disposal

• Do not flush the tablets or throw them in the household trash
• Consult your pharmacist or local waste disposal service for safe disposal instructions

Generic vs Branded Comparison

Important Note

Alkacel Melphalan 2 mg Tablet is a powerful chemotherapy medicine and should only be taken under the supervision of a qualified oncologist. Regular monitoring and strict adherence to medical advice are essential for safe and effective cancer treatment.