Milrineon 10mg Injection

Milrineon 10 mg Injection contains milrinone, a phosphodiesterase-3 (PDE3) inhibitor used in the short-term management of severe heart failure. It is administered intravenously in hospital settings to improve heart function in patients with acute decompensated heart failure.

This medicine is typically used in intensive care or cardiac care units under strict medical supervision.

Indications

Milrineon 10 mg Injection is indicated for:

• Short-term treatment of acute heart failure

• Patients with reduced cardiac output

• Supportive therapy in patients awaiting advanced cardiac intervention

It is not intended for long-term outpatient therapy.

Mechanism of Action

Milrinone works by inhibiting phosphodiesterase type 3 (PDE3).

Blocking this enzyme increases intracellular cyclic AMP levels in cardiac muscle and vascular smooth muscle. This leads to:

• Improved myocardial contractility (positive inotropic effect)

• Reduced vascular resistance (vasodilation)

• Improved cardiac output

The combined effect helps the heart pump more efficiently.