Osimert 80 mg – Generic Tagrisso

Osimert 80 mg, manufactured by Everest Pharmaceuticals, is a popular prescription medicine for treating non-small cell lung cancer (NSCLC). This medicine’s active ingredient is Osimertinib, and it functions by blocking the EGFR protein, the main source of growth in cancer cells. By blocking this protein, Osimertinib helps to slow tumour progression and alleviate symptoms such as coughing and difficulty breathing.

Osimert 80mg is typically taken as a single, whole tablet once a day. One of its key advantages is that it tends to cause fewer side effects compared to traditional chemotherapy treatments. Proper medical supervision is necessary before taking this medicine.

Key Benefits of Osimert 80

Here are some common distinguishing benefits of Osimert 80mg:

• Osimert 80mg particularly targets EGFR mutations that are responsible for the growth of cancer cells. This kind of focused intervention disrupts the process and hinders cancer progression at its core.
• Osimert 80mg is especially beneficial for patients who have developed resistance to first-generation EGFR inhibitors. This medicine is not only used as an effective treatment option but also serves as a line of defence against cancer.
• As per the clinical evidence, it is suggested that Osimert 80mg by Everest Pharma significantly contributes to progression-free survival in patients with advanced NSCLC. By slowing tumour growth, it offers hope for extending life and alleviating disease progression, improving patients’ overall prognosis.
• Unlike traditional chemotherapy, Osimert 80mg primarily targets cancer cells, minimizing harm to healthy, normal cells. This selective action reduces side effects and helps enhance the body’s tolerance to the medication, making the treatment more manageable for patients.

How Does Osimert 80 Work?

Osimert 80mg, commonly known as Tagrisso Generic, is a powerful medicine for treating lung cancer. It works well by blocking the EGFR protein, which is the root cause of cancer cells growing. This protein component keeps on changing among lung cancer patients and thus the disease becomes difficult and challenging to cure. In many lung cancer patients, the EGFR protein undergoes mutations, which allow cancer cells to grow uncontrollably.

It also lowers the growth of tumours, improving breathing and coughing over time. Before taking this medicine, patients should follow doctors’ instructions carefully.

For individuals with pre-existing lung or heart conditions, it is crucial to monitor these aspects regularly while using Osimert 80mg, as the medication may have some impact on these organs. When used correctly, Osimert 80mg can provide significant relief and improve the quality of life for patients, helping them manage the disease and live longer.

Dosage and Administration of Osimert 80

Here is how Osimert should be administered:

• The recommended dosage of Osimert 80mg by Everest Pharma is once daily until disease progression occurs or if unacceptable toxicity is observed.
• Individuals can take this medicine both with and without food.
• If you miss any dosage of Osimertinib, do not go for the missed dose; instead, take the next dose as scheduled.
• If there is difficulty in swallowing solids, the Osimert 80mg tablet should be dissolved into 4 tablespoons of noncarbonated water only. Continue stirring until it is completely dispersed, and then swallow it through a nasogastric tube immediately.
• Make sure not to heat, crush, or ultrasonicate during preparation.

Strengths and Substitutes of Osimert 80

Osimert 80mg helps to treat non-small cell lung cancer (NSCLC) with EGFR mutations. It primarily targets cancer cells, slows tumour growth, and enhances patient survival rates. It has fewer side effects than traditional chemotherapy, making it suitable and convenient for patients.  There is only one strength of Osimert, which is 80mg.

The most popular substitute for Osimert 80mg is Tagrisso 80mg. Both medications contain the same active ingredients, but Tagrisso is a popular brand name manufactured by AstraZeneca. However, there are quite a few more substitute medications available:

• Tagrisso Osimertinib 80mg Tablets
• Ositab 80mg Tablet
• Irmukin 80mg Tablets
• Tasso 80mg Tablets
• Osimatab 80mg Tablet
• Tagrix Osimertinib 80mg Tablets
• Osikin 80mg Tablets
• Osicent Osimertinib 80mg Tablets
• Osinib 80mg Tablets
• Tasso 80mg Tablets
• Osmigen 80mg Tablets

Side Effects of Osimert 80

Some of the common side effects of Osimert 80mg include the following:

• Diarrhea
• Tired feeling
• Loss of appetite
• Mouth sores
• Dry skin
• Rash
• Discolouration
• Pain
• Infection
• Problems with fingernails or toenails

Some other more serious side effects include:

• Shortness of breath with mild exertion
• The feeling of lightheadedness, you might pass out
• Fast heartbeat
• Swelling
• Fast weight gain
• Worsening of lung symptoms such as discomfort, chest pain, dry cough, wheezing, shortness of breath and others
• Eye problems – changes in vision, watery eyes, eye pain, redness, increased sensitivity to light

Safety and Precautions of Osimert 80

Osimert 80 is one of the popular and targeted treatments used for treating non-small cell lung cancer (NSCLC) with specific genetic mutations. With its effectiveness, it needs close monitoring because of its potential side effects.

Patients should follow the medical guidance and undergo check-ups on a regular basis to ensure safety. Let us explore the safety and precautions of Osimert 80 in detail below:

• Interstitial Lung Disease (ILD): Commonly known as pneumonia, patients diagnosed with this disease should permanently discontinue this medicine.
• Cardiomyopathy: Before starting Osimert 80mg, a patient’s left ventricular ejection fraction (LVEF) should be assessed. Regular monitoring of LVEF should continue every 3 months during treatment to detect any potential signs of cardiomyopathy.
• QTc Interval Prolongation: Patients with a history of QTc prolongation or those who take medicines for prolonging the QTc interval should keep daily monitoring of electrolytes and electrocardiograms. If significant QTc prolongation is observed, Osimert 80mg may need to be withheld and later reintroduced at a reduced dose, or it may need to be permanently discontinued.
• Keratitis: Patients should inform their healthcare provider immediately if they are suffering from this eye disease and have symptoms such as lacrimation, eye inflammation, pain in the eyes, light sensitivity, redness in the eyes, and changes in vision.
• Embryo Fetal Toxicity: Osimert 80mg can cause significant harm to a developing fetus, making it unsafe for pregnant women. Females of childbearing potential should use effective contraception during treatment with Osimert and continue for 6 weeks after the last dose. On the other hand, males should use effective contraception for 4 months after the final dose to prevent potential exposure to the drug through semen.

Consult with your doctor to see if Osimert 80mg is suitable for you. Make sure to follow the medical advice carefully and do not start consuming the medicine without consultation from a healthcare professional.

Frequently Asked Questions

• What is Osimert 80mg specifically used for?

Osimert 80mg medication treats non-small cell lung cancer (NSCLC) with EGFR mutations. It slows the growth of cancer cells and improves breathing and coughing problems.

• How should I consume Osimert 80mg?

Take Osimert 80mg daily with or without food. Swallow this medicine as a whole with water. Make sure not to crush or break the tablet while consuming.

• What might happen if a dose of Osimert 80mg is missed?

If you have missed a dose of Osimert 80mg and 12 hours have passed, skip the missed dose and continue with your next scheduled dose.

• Can Osimert 80mg cure lung cancer?

Osimert 80mg is not a cure for lung cancer, but it helps to control it. It slows down the growth of tumours, reduces symptoms and improves the quality of life.

• What are the most common side effects of Osimert 80mg?

Some of the most common side effects of Osimert 80mg include dry skin, nausea, skin rash, diarrhoea, and fatigue. Some people also experience heart or lung issues. If these side effects persist for a long time or worsen, contact your doctor immediately.

• Will it be beneficial to take Osimert 80mg with other medications?

Yes, Osimert 80mg can be consumed with other medications. Make sure to inform your doctor about all the medications and supplements you are taking.

• Is Osimert 80mg safe during pregnancy?

No, Osimert 80mg is unsafe to consume during pregnancy. It might affect an unborn baby.

• Is alcohol consumption normal while taking Osimert 80mg?

No, there is no direct connection between Osimert 80mg and alcohol, but alcohol can worsen the side effects, such as fatigue and nausea. It is advisable to consult your doctor about alcohol consumption.

• For how long do doctors prescribe taking Osimert 80mg?

The treatment duration of Osimert 80mg depends on how you are responding to the medication. For some patients, it can take several months or even years. It is the doctor’s responsibility to monitor progress and determine the best treatment plan.

•  What should I do if I experience severe side effects of Osimert 80mg?

If you experience severe side effects like difficulty breathing, vision issues, diarrhoea, chest pain, or others, seek immediate help from your doctor.

Disclaimer: This information is only for educational purposes. Always consult a doctor before using Osimert 80mg. Carefully follow your doctor’s instructions and attend regular check-ups. If you experience any side effects or unusual symptoms, report them to your healthcare provider immediately.

References

https://pmc.ncbi.nlm.nih.gov/articles/PMC11315406/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6516134/

https://www.researchgate.net/publication/381124538_Phase_II_Efficacy_and_Safety_of_80_mg_Osimertinib_in_Patients_With_Leptomeningeal_Metastases_Associated_With_Epidermal_Growth_Factor_Receptor_Mutation-Positive_Non-Small_Cell_Lung_Cancer_BLOSSOM

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