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9 Best ED Pills That Will Improve Your Sexual Life

Best ED Pills

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A fulfilling sex life is essential for overall well-being, yet millions of men worldwide struggle with Erectile Dysfunction (ED). Fortunately, there are several ED pills available in the market that help men take control and enhance their intimate relationships. 
In this blog, we will discuss the different types of ED medications and pills, highlighting their benefits and side effects. 

What is Erectile Dysfunction?

Erectile Dysfunction (also called Impotence) is one of the most common sexual disorders seen in men. This disorder is associated with the inability to get or maintain an erection long enough for intercourse. 
Facing this issue is not uncommon in men from time to time. However, consulting a doctor is essential if you regularly experience it. However, the disorder is treatable through various means. Common symptoms of ED are:

  • Low libido

  • Inability to maintain an erection 

  • Flaccid penis

ED can result from psychological factors, lifestyle habits, or age-related changes. While addressing underlying health issues can improve symptoms, ED pills provide a direct solution for men seeking immediate relief.

Types of ED Pills

Erectile Dysfunction can be treated with different types of pills available on the market. These pills react with your body to help you maintain a firm erection for satisfying sexual intercourse. 

  • Sildenafil Citrate

Sildenafil Citrate, commonly known as Sildenafil, is a medication that treats erectile dysfunction (ED) as well as PAH or pulmonary arterial hypertension. It belongs to a class of drugs called Phosphodiesterase type 5 (PDE5) inhibitors, which help improve blood flow by relaxing blood vessels.
Sildenafil has the chemical formula C₂₂H₃₀N₆O₄S. It works by inhibiting the PDE5 enzyme, thereby increasing cyclic guanosine monophosphate (cGMP) levels. This results in enhanced blood flow and makes it easier to achieve and maintain an erection when sexually stimulated. 
Viagra 100, manufactured by Pfizer, is the leading branded and FDA-approved ED pill containing Sildenafil Citrate. Another medication, Cenforce 200, which also contains Sildenafil, is marketed by Centurion Laboratories.

  • Avanafil

Avanafil is another PDE5 inhibitor known for its rapid onset of action, making it a preferred choice for those seeking faster results in ED pills. Unlike Sildenafil, Avanafil has a lower likelihood of side effects.
The chemical formula for Avanafil is C₂₃H₂₆ClN₇O₃. It functions similarly to Sildenafil by enhancing blood flow to the penile area, resulting in longer-lasting erections. However, it is considered superior to Sildenafil due to its fewer side effects and faster onset of action. 
Branded erectile dysfunction pills, such as Stendra 100, manufactured by Vivus Incorporated, contain avanafil. Another medication containing avanafil is Avana 100, manufactured by Sunrise Remedies. 

  • Tadalafil

Tadalafil, also dubbed the 'weekend pill', is a drug used to treat Erectile Dysfunction. It follows the exact mechanism as Sildenafil, with a slightly longer duration of action. 
Tadalafil’s chemical formula is C₂₂H₁₉N₃O₄, and it lasts up to 36 hours in the human body, making it ideal for spontaneous sexual activity. 
A widely prescribed branded medication that contains Tadalafil is Cialis, manufactured by Eli Lilly and Company. Another frequently prescribed brand is Vidalista Black 80.

  • Vardenafil

Vardenafil is also a phosphodiesterase type 5 (PDE5) inhibitor used to treat Erectile Dysfunction in men. It works by increasing blood flow to the penis, thus causing an erection. However, it does not cure erectile dysfunction or increase sexual desire. 

The chemical formula for Vardenafil is C23H32N6O4S, and it typically lasts 4 to 6 hours in the human body. Vardenafil is primarily marketed under the brand names Levitra 20 mg (Bayer Pharmaceuticals) and Vilitra (Centurion Laboratories).

How do ED Pills Work?

Erectile dysfunction (ED) medications, including Viagra, Cialis, and Levitra, assist men in achieving and sustaining an erection suitable for sexual activity by enhancing the body's natural erection process. Here is how it works:

  • The Role of Nitric Oxide: When a man is sexually aroused, the brain signals the release of nitric oxide in the penis. This chemical relaxes the smooth muscles in the penile tissue, allowing blood to flow into the spongy chambers (corpora cavernosa and corpus spongiosum), leading to an erection.

  • The Role of PDE5 Inhibitors: In some men, an enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP too quickly, preventing sufficient blood flow to the penis. ED pills inhibit the function of PDE5, allowing cGMP to remain active longer. This results in improved blood flow and helps maintain an erection during sexual stimulation. 

  • Common Misconceptions About ED Pills: There are many misconceptions about the effectiveness of these medications. Here is a list of them: 

    • Sexual Stimulation is Not Required: Erection pills do not cause spontaneous erections; sexual arousal is necessary for them to work. 

    • Timing: These medications are typically taken before sexual activity. The onset of action varies; some may work within 15 minutes, while others might take up to an hour.

    • Consultation is Necessary: Always consult a healthcare provider before using ED pills, especially if you have underlying health conditions or take other medications.

By supporting the body’s natural processes, ED medications can significantly improve sexual function for many men, provided they are used correctly and under medical supervision. 

9 Best ED Pills That Help Treat ED

Before purchasing or using any erectile dysfunction medications, consult a doctor. With that said, here are the best medications available to help treat ED:

  1. Avana Avanafil 100

Avana 100 mg is a prescription medication used to treat erectile dysfunction (ED) in men. It contains Avanafil, a PDE5 inhibitor that enhances blood flow to the penis during sexual stimulation, helping men achieve and maintain an erection.
Dosages of Avanafil are available in 50 mg, 100 mg, and 200 mg. It has a relatively quick onset period of about 15 minutes, although this may vary from person to person. The maximum duration of action for Avanafil is 6 hours.
The common side effects of Avana Avanafil include:

  • Flushing

  • Headache

  • Dizziness

  • Back pain and muscle aches

  • Nasal congestion

Apart from all these common side effects, rare side effects may also appear, which are: 

  • Priapism, that is, a painful and prolonged period of erection

  • Hearing loss

  • Vision changes

  • Allergic reactions 

If you experience any of these rare side effects, especially priapism, hearing loss, or vision changes, seek medical attention immediately.

  1. Cenforce Sildenafil 100

Cenforce 100 is an effective medication for treating erectile dysfunction (ED). The active ingredient in Cenforce 100 is Sildenafil Citrate, which is a PDE-5 inhibitor.
This medication is available in various strengths, including 25 mg, 50 mg, 100 mg, 150 mg, and 200 mg tablets. The onset of action can vary from person to person, but on average, it typically takes between 30 minutes to an hour to start working. The effects generally last for about 3 to 4 hours.
Some of the common side effects of Cenforce are: 

  • Distortion of vision

  • Rashes 

  • Dizziness

  • Nausea

  • Clogged nose

  • Muscle aches

  • Flushing, a warm sensation in the cheeks, ears, neck, and trunk

  • Indigestion

  1. Viagra Sildenafil 

Viagra, manufactured by Pfizer Inc., is a well-known medication used to treat erectile dysfunction (ED) in men. Sildenafil, its active ingredient, belongs to a class of drugs called PDE5 inhibitors, which enhance blood flow to the penis during sexual stimulation.
Viagra is available in a variety of strengths ranging from 25 mg to 100 mg. It typically begins to take effect within 30 to 60 minutes after taking the pill and should reach its maximum effectiveness within 2 hours. The effects usually last 4 to 5 hours.
Some common side effects of Viagra include:

  • Headaches

  • Nausea

  • Flushing

  • Stuffy nose

  • Dizziness

Some serious side effects, which require medical attention, include: 

  • Sudden loss of vision

  • Serious allergic reaction

  • Serious chest pains

  • Painful and prolonged erection. 

If you face a prolonged and painful erection or sudden loss of vision, contact your doctor immediately. 

  1. Kamagra Chewable Tablets

This generic Sildenafil tablet is classified as a phosphodiesterase type 5 (PDE5) inhibitor. Similar to Viagra, it works by enhancing blood flow to the penile area, stimulating an erection. 
These tablets dissolve quickly and are absorbed into the bloodstream very quickly. The medication starts to take effect after about 30 minutes and lasts 3-5 hours. 
The common side effects of Kamagra include: 

  • Blurred vision

  • Muscle pain

  • Flushing

  • Indigestion

  • Upset stomach

  • Rashes

  • Dizziness 

  • Nausea

  • Stuffy or clogged nose

These side effects are generally a result of your body reacting to a new medication and typically subside over time. 

  1. Cialis Tadalafil 10

Cialis (tadalafil) 10 mg is a tablet used to treat erectile dysfunction. It belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors and is manufactured by Eli Lilly and Company. The drug has received approval from the Food and Drug Administration (FDA) for use in adults to address ED. 
It comes in 2.5 mg, 5 mg, 10 mg, and 20 mg tablets and takes about 30 minutes to take effect in a person’s body. The effects of Cialis may last up to 36 hours in a person’s body (dubbed the "weekend pill" for this effect). 
Some of the side effects of Cialis are: 

  • Headaches

  • Nausea

  • Clogged nose

  • Indigestion

  • Muscle aches

  1. Extra Super Tadarise

Sunrise Remedies manufactures Extra Super Tadarise, a product containing two active ingredients: Tadalafil and Dapoxetine. Tadalafil is a PDE5 inhibitor that helps treat erectile dysfunction (ED) by relaxing the smooth muscles in the blood vessels of the penis, thereby improving blood circulation. 
Dapoxetine, on the other hand, is a Selective Serotonin Reuptake Inhibitor (SSRI) that enhances control over ejaculation. Together, these ingredients work to address both erectile dysfunction and premature ejaculation effectively. 
It is available in 40 mg and 60 mg strengths, to be taken orally. As its active ingredient is Tadalafil, it takes about 30 minutes to take effect, and the effects last for about 36 hours. 
The common side effects of Extra Super Tadarise are as follows:

  • Flushing

  • Headaches

  • Dizziness

  • Nausea

Some of the rare side effects are listed below. Consult a doctor if you face any. 

  • Indigestion

  • Back pain

  • Abdominal pain

  • Vision changes

  • Hearing loss

  • Priapism (prolonged and painful erections).

  1. Levitra Vardenafil 

Manufactured by Bayer Healthcare Pharmaceuticals Inc., Levitra Vardenafil is a phosphodiesterase type 5 inhibitor drug prescribed to treat male impotence. However, it does not boost sexual desire in itself and only works when the person is sexually stimulated. 
Levitra is available in 5 mg, 10 mg, and 20 mg strengths, and the drug is effective in about 30 to 60 minutes and lasts for approximately 4 hours. 
Some of the side effects of Levitra Vardenafil include,

  • Dyspepsia

  • Flu-like symptoms

  • Sinus inflammation 

  • Dizziness

  • Back pain

  • Nausea

  • Headache

  • Increased creatine levels in the blood.

  1. Vilitra 60

Vilitra 60 is a medicine that contains Vardenafil as its main ingredient. This also belongs to the category of phosphodiesterase type 5 inhibitor medications. Centurion Laboratories, a renowned name in the pharmaceutical industry, manufactures Vilitra. 
Vilitra 60 comes in different strengths like 20 mg, 40 mg, and 60 mg. The onset of action for Vilitra 60 is between 30 and 60 minutes, and its effects last 4 to 6 hours.
The side effects of Vilitra 60 are as follows:

  • Upset stomach

  • Headaches

  • Dizziness

  • Vision changes

  • Priapism 

  • Nasal congestion

  • Flushing

  • Allergic reactions

  1. Vidalista Black 80

Vidalista Black 80 is produced by Centurion Laboratories, and its active ingredient is Tadalafil. This medication improves blood flow to the penis. It is available exclusively in an 80 mg strength. The effects typically take 30 to 60 minutes to become noticeable and can last approximately 36 hours.
Some common side effects of Vidalista Black 80 are:

  • Headache

  • Flushing

  • Dizziness

  • Back pain

  • Clogged nose

  • Muscle aches

These side effects are mild and usually go away on their own. However, the following side effects are serious and require immediate medical intervention.

  • Sudden vision loss

  • Hearing loss

  • Irregular heartbeat

  • Fainting

  • Priapism

Dosages of ED Pills

Always follow your doctor's recommended dosage and avoid self-medication. They will determine the best dosage to fit your needs.
Sildenafil25, 50,10050 mg
Avanafil50, 100, 200100 mg
Tadalafil2.5, 5, 10, 2010 mg
Vardenafil2.5, 5, 10, 2010mg

When are ED Pills Not Safe?

Certain conditions and medications may make ED pills unsafe. Avoid these medications if you:

  • Nitrate Medicines: These medicines are commonly prescribed for chest pain (also called angina). People who are taking nitrates like Isosorbide Dinitrate (Isordil) or Nitroglycerin (Nitrostat) should avoid these pills. The combination of these two medications is dangerous and can cause severe hypotension (low blood pressure). 

  • Alpha-blockers: These medications are typically prescribed to treat an enlarged prostate or male pattern baldness. Examples include Doxazosin (Cardura) and Dutasteride (Avodart, Jalyn).

  • CYP3A4 Enzyme Blocking Medicines: Some medications, such as ritonavir, can slow the breakdown of ED drugs like Viagra, leading to increased levels in the body and a higher risk of side effects. Other CYP3A4 inhibitors include Itraconazole (Sporanox, Tolsura) and Ketoconazole (Extina, Ketozole).

Oral medicine for erectile dysfunction also might not work or be safe if you have the following conditions:

  1. Hypotension, or very low blood pressure.

  2. Hypertension, or uncontrolled high blood pressure.

  3. Severe liver disease or kidney disease that requires dialysis.

  4. Recent heart or blood vessel problems (within the past six months), including heart attacks, strokes, or life-threatening arrhythmias

  5. Eye diseases such as non-arteritic anterior ischemic optic neuropathy (NAION) or retinitis pigmentosa

  6. Allergies to ED pills

To ensure safe treatment, always disclose your complete medical history to your doctor and exercise caution.

How to Buy ED Pills Online?

Many websites sell ED pills online, but be cautious of scams and unreliable sites offering counterfeit medications. If you are willing to buy ED pills online, you may purchase them from the Indogenmed website: 

  1. Obtain a Prescription: In the USA, Sildenafil, Avanafil, Tadalafil, and Vardenafil require a doctor’s prescription. Some reputable online pharmacies offer telehealth consultations, allowing licensed healthcare professionals to assess your condition and prescribe medication if appropriate.  

  2. Choose a Reputable Pharmacy: Avoid those online pharmacies that do not list their phone numbers or physical addresses. Avoid websites offering ED pills without a prescription or at suspiciously low prices, as they may sell counterfeit drugs.

  3. Verify Legitimacy: In the United States, you can check the legitimacy of online pharmacies through the National Association of Boards of Pharmacy. 

Final Thoughts

Erectile Dysfunction is a common but treatable condition affecting men. While addressing underlying health issues can often improve symptoms, ED pills provide an effective solution for those seeking immediate results.
However, it is crucial to avoid self-medication and talk to your doctor to ensure safety. With the proper medication and approach, men can regain control over their sexual lives. You should always prioritize making informed choices based on the advice of a licensed healthcare professional. 

Frequently Asked Questions

  1. Are ED Pills prescription only?

Yes, Erectile Dysfunction medicines are prescription-only drugs and cannot be obtained over the counter. Always consult your doctor before taking ED pills. 

  1. Are ED medicines safe?

Yes, erectile dysfunction (ED) medications are generally safe when taken as prescribed. However, they may cause side effects such as dizziness, headaches, or gastrointestinal issues. Individuals with serious heart conditions, kidney disease, or those taking certain medications should exercise caution.

  1. Do erectile dysfunction pills work?

Yes, Erectile Dysfunction medications are clinically proven to help men achieve and maintain an erection by increasing blood flow to the penis. However, to be effective, sexual stimulation is essential.

  1. Can I take ED pills with blood thinners?

While erectile dysfunction (ED) pills are usually safe to take alongside blood thinners, it's essential to consult a doctor before combining these medications. Individuals diagnosed with pulmonary hypertension have a higher risk of bleeding when using both blood thinners and ED pills. 

  1. Which is the best pill for ED?

The best pill to treat ED largely varies depending on individual needs. Sildenafil (Viagra) works quickly but lasts only for a few hours, whereas Tadalafil (Cialis) lasts up to 36 hours. On the other hand, Avanafil offers a faster onset with fewer side effects. The best way to determine the most suitable option is to consult a doctor.

  1. How long do ED pills last?

The duration mainly depends on the type of pill used.

  • Sildenafil: 4 – 6 hours

  • Tadalafil: Up to 36 hours

  • Avanafil: 6 – 12 hours

  • Vardenafil: 4 – 6 hours

  1. Is Viagra the best pill for ED?

Viagra is one of the most well-known brands when it comes to treatment for Erectile Dysfunction, but whether or not it is the best pill depends on individual needs. People may also prefer Cialis for its long-lasting effects or Stendra for its fewer side effects. 

  1. How many inches does Viagra give you?

Viagra does not increase penis size. It enhances erections by directing blood flow to the penis, which may create the illusion of a size increase.

  1. Can you take ED pills without having erectile dysfunction?

No, you should not take ED pills without having any sexual disorders. This pill does not enhance sexual performance and should strictly be taken under medical supervision. 

  1. Are tablets the only option for ED treatment? 

No, ED medications come in different forms. In addition to traditional tablets, oral jelly is also available as an alternative. Oral jelly works similarly to tablets but may be absorbed faster, making it a preferred option for some individuals.
Do not compromise on quality when it comes to your health. Indogenmed offers trusted, doctor-approved ED medications delivered discreetly to your door. Take the first step toward confidence and order now!
Disclaimer: Always disclose your medical history to your doctor before using ED medication. Use only as prescribed, and seek medical attention if you experience any adverse effects.
Reference links:

https://www.webmd.com/erectile-dysfunction/erectile-dysfunction-treatment

https://www.mayoclinic.org/diseases-conditions/erectile-dysfunction/symptoms-causes/syc-20355776

https://my.clevelandclinic.org/health/diseases/9127-penile-disorders

https://www.drugs.com/sildenafil.html

https://medlineplus.gov/druginfo/meds/a603035.html

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Renu Meena

Renu Meena is an experienced Medical Content Writer with a strong foundation in pharmacy practice. She holds a Bachelor of Pharmacy (B.Pharm) degree from Rajasthan University of Health Sciences (RUHS), Jaipur, and has 4+ years of experience across clinical pharmacy and medical content development.
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