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Tucanat 150 mg Tablet

Tucanat 150 mg Tablet

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Description

Tucanat 150mg Tablet is a treatment for a type of breast cancer called HER2-positive breast cancer. It is beneficial when the cancer has spread to other parts of the body, including the brain. It is usually taken together with two other medicines: trastuzumab and capecitabine.

The main ingredient, Tucatinib, works by blocking the HER2 protein that helps cancer cells grow. This helps slow down or stop the cancer from spreading.

Tucatinib is not chemotherapy. It is a targeted therapy, meaning it primarily targets cancer cells and is less harmful to normal cells. It must be taken only as prescribed by a doctor, with regular checkups during the treatment.

Tucanat 150mg Tablet is used for:

  • HER2-positive breast cancer that has spread or become advanced

  • Breast cancer that has spread to the brain

  • Given with trastuzumab and capecitabine after other HER2 treatments stop working

This medicine is usually used when earlier treatments have become ineffective.


How It Works

Tucanat 150mg Tablet belongs to a group of medicines called tyrosine kinase inhibitors.

It works by:

  • Targeting the HER2 protein that helps cancer cells grow

  • Blocking signals that allow cancer cells to multiply

  • Working together with other cancer medicines

  • Reaching cancer that has spread to the brain

This helps slow the disease while avoiding damage to healthy cells.


Drug Interactions

Tell your doctor about every medicine, supplement, or herbal product you are taking.

Some medicines can affect how Tucanat works, such as:

  • Certain antifungal medicines

  • Some antibiotics

  • Rifampin-type medicines

  • Seizure medications

  • St. John’s Wort

  • Some medicines for acidity or stomach issues

These can increase side effects or reduce Tucanat's effectiveness.


Storage

  • Store below 30°C and keep away from sunlight.

  • Keep the tablets in the original packaging until use.

  • Do not freeze.

  • Keep away from children.

  • Dispose of unused or expired tablets safely. Don’t flush them.


How to Take It

  • Take it exactly as your cancer doctor tells you.

  • Usually taken twice daily (every 12 hours), with or without food.

  • Swallow whole, don’t crush or chew.

  • Try to take it at the exact times every day.

  • If you vomit after taking it, don’t take another dose — wait for the next one.

  • Don’t skip doses or stop taking it unless your doctor tells you to.


Safety Advice

Pregnancy: Do not use during pregnancy. Women should use contraception during treatment and for at least one week after the last dose.

Breastfeeding: Do not breastfeed while taking this medicine.

Liver: Regular liver tests are required because the medicine can affect liver function.

Lungs: Use only under strict doctor supervision. Report breathing issues immediately.

Alcohol: Avoid alcohol — it may worsen liver side effects.

Some people feel dizzy or tired — be cautious when driving.

Side Effects

Common Side Effects

Some people may experience:

  • Diarrhea

  • Tiredness

  • Nausea or vomiting

  • Mouth sores

  • Loss of appetite

  • Red or sore hands and feet

  • Changes in liver test results

These often improve over time. Tell your doctor if they become severe or persist.

Serious Side Effects — Contact Your Doctor Immediately

  • Yellow skin or eyes

  • Heavy diarrhea with weakness

  • Breathing difficulty or swelling

  • High fever or infections

Helpful Tips

  • Keep ORS (oral rehydration solution) handy for diarrhea.

  • Use sunscreen and moisturizer if your skin becomes sensitive.

  • Eat mild, non-spicy foods if you have nausea.

  • Inform your doctor about any over-the-counter medications you take.

  • Track your symptoms daily — it helps your doctor guide your treatment.

FAQs 

Q1: What is Tucanat 150mg used for?
For HER2-positive breast cancer that has spread, including to the brain. Often used after other treatments stop working.

Q2: How is this different from chemotherapy?
It targets only cancer cells that express the HER2 protein, causing fewer side effects in normal cells.

Q3: What is the usual dose?
Typically 300mg twice daily — meaning two 150mg tablets in the morning and two in the evening.

Q4: What if I miss or vomit a dose?
If more than 8 hours have passed, skip it and continue with your normal schedule. Don’t double the dose. If you vomit after taking it, don’t re-take — wait for the next dose.

Q5: Can it help with cancer that spreads to the brain?
Yes. Tucatinib can reach the brain and help control cancer there.

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