Description
Extra Super Vilitra | Dual-Action Vardenafil & Dapoxetine Guide
Extra Super Vilitra is a high-potency, dual-action prescription medication engineered to treat two co-occurring male sexual dysfunctions simultaneously: severe Erectile Dysfunction (ED) and Premature Ejaculation (PE). Manufactured by Centurion Laboratories, each tablet combines two active compounds:
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Vardenafil (40 mg): A potent phosphodiesterase type-5 (PDE5) inhibitor formulated at an extra-strength dose to dilate pelvic blood vessels and restore firm erectile rigidity.
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Dapoxetine Hydrochloride (60 mg): A short-acting selective serotonin reuptake inhibitor (SSRI) specifically designed to delay the ejaculatory reflex and enhance climax control.
Critical Medical Warning
Extra Super Vilitra delivers a high-potency combination. Standard single-agent Vardenafil therapies max out at 20 mg; this formulation contains an off-label 40 mg dose of Vardenafil paired with 60 mg of Dapoxetine. This dual-action medication acts on both vascular smooth muscle and central serotonergic pathways. It must only be taken under strict medical supervision by a licensed physician or urologist.
How Extra Super Vilitra Works: Dual Mechanism of Action
Extra Super Vilitra coordinates two distinct biological mechanisms within a single tablet to manage both erection rigidity and ejaculatory timing.
1. Vascular Erection Support (Vardenafil 40 mg)
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Arousal & Nitric Oxide Release: Sexual stimulation prompts local non-adrenergic, non-cholinergic (NANC) nerves and endothelial cells in the penis to release Nitric Oxide (NO).
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Enzyme Activation: NO stimulates the enzyme guanylate cyclase, which synthesizes cyclic guanosine monophosphate (cGMP).
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Smooth Muscle Relaxation: cGMP relaxes smooth muscle tissues within the corpora cavernosa, allowing blood to engorge penile tissue under pressure.
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Selective PDE5 Blockade: Vardenafil selectively binds to the PDE5 enzyme, stopping the premature breakdown of cGMP.
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Sustained Engorgement: Elevated cGMP levels keep the helicine arteries dilated, maintaining a firm erection throughout the intimate encounter.
2. Ejaculatory Delay & Reflex Control (Dapoxetine 60 mg)
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Central Serotonin Reuptake Inhibition: Ejaculation is primarily mediated by the sympathetic nervous system, coordinated in the brain and spinal reflex arcs.
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Elevated Synaptic Serotonin: Dapoxetine selectively blocks the serotonin transporter (SERT), inhibiting the reuptake of serotonin (5-HT) into presynaptic neurons.
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Delaying the Climax Reflex: Increased serotonin levels at the synaptic cleft stimulate 5-HT2C receptors, which increases the sensory threshold required to trigger the ejaculatory reflex, delaying climax.
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Requires Sexual Stimulation: Extra Super Vilitra does not generate an unprompted erection. Natural psychological or physical arousal is necessary to initiate the vascular pathway.
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No Aphrodisiac Effects: This pill does not influence testosterone levels, central libido, or subjective sexual desire.
Product Quick Summary
| Specification Feature | Clinical Details |
| Brand Name | Extra Super Vilitra |
| Active Ingredients | Vardenafil (40 mg) + Dapoxetine HCl (60 mg) |
| Pharmacological Class | PDE5 Inhibitor (Vasodilator) + Short-Acting SSRI |
| Primary Indications | Severe Erectile Dysfunction & Premature Ejaculation |
| Manufacturer | Centurion Laboratories Pvt. Ltd. |
| Dosage Form | Swallowable oral film-coated tablet |
| Onset Window | Approximately 30 to 60 minutes |
| Therapeutic Window | 4 to 5 hours for Vardenafil; 2 to 4 hours for peak Dapoxetine |
| Prescription Status | Prescription-only medicine |
Available Strengths
Clinical Advantages of the Dual Formulation
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Unified Treatment: Simultaneously targets the physical vascular inability to achieve rigidity and the neurochemical impulse to climax prematurely.
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High-Strength Vascular Efficacy: The 40 mg Vardenafil dosage provides high receptor occupancy for men with persistent ED resistant to standard 20 mg formulations.
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Fast Pharmacokinetics: Vardenafil acts quickly (often within 25–40 minutes), and Dapoxetine is rapidly absorbed and eliminated, reducing the risk of prolonged next-day SSRI side effects.
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Improved Sexual Confidence: Eliminates performance anxiety tied to both losing firmness and climaxing too quickly.
Dosage, Administration & Best Practice Protocols
Adhering to strict administration guidelines ensures optimal therapeutic action while minimizing potential drug-drug interactions:
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Administration: Swallow one tablet whole with a full glass of plain water. Do not chew, crush, break, or dissolve the tablet.
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Timing: Take the medication 45 to 60 minutes before planned sexual activity to allow both Vardenafil and Dapoxetine to achieve therapeutic blood levels simultaneously.
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Dietary Factors: Can be taken with or without food. Taking it on an empty stomach supports optimal absorption. Avoid consuming heavy or high-fat meals directly before dosing, as excessive dietary lipids can delay gastric emptying and slow the onset of Vardenafil.
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Strict Daily Cap: Do not exceed one tablet within 24 hours. Exceeding this limit causes extreme vascular and neurological strain, elevating the risk of fainting, sudden hypotension, and serotonin toxicity.
Potential Side Effects & Safety Profile
Because this formulation contains both a vasodilator and an SSRI, patients may encounter transient side effects during absorption:
Common & Mild Side Effects
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Headaches and lightheadedness
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Facial flushing, redness, or neck warmth
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Mild nausea or stomach discomfort (primarily driven by Dapoxetine)
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Nasal congestion or runny nose
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Dizziness upon standing (postural hypotension)
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Dry mouth or insomnia
Serious Adverse Reactions (Seek Immediate Emergency Care)
Discontinue use and seek urgent emergency medical attention if any of the following occur:
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Priapism: An erection that remains rigid, painful, and persists longer than 4 hours. Without prompt urological care, ischemic priapism can result in permanent penile fibrosis and irreversible ED.
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Sudden Vision or Hearing Loss: Abrupt loss of sight (symptom of NAION) or sudden bilateral/unilateral hearing reduction.
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Cardiac Distress: Angina (chest pain), irregular heartbeat, severe dyspnea, or syncope during sexual activity.
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Serotonin Toxicity / Syndrome: Signs of confusion, high fever, shivering, excessive sweating, hyperreflexia, or severe tremors.
Critical Contraindications & Drug Interactions
Critical Nitrate & Psychiatric Warnings
Never take Extra Super Vilitra alongside organic nitrates (nitroglycerin, isosorbide mononitrate/dinitrate, or recreational “poppers” like amyl nitrite). Combining Vardenafil with nitrates causes catastrophic, irreversible drops in systemic blood pressure that can be fatal.
Never combine with psychiatric medications, including Monoamine Oxidase Inhibitors (MAOIs), Selective Serotonin Reuptake Inhibitors (SSRIs), Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs), Tricyclic Antidepressants (TCAs), or Lithium. Allow a 14-day washout period between these medications and Dapoxetine to avoid Serotonin Syndrome.
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QT Prolongation & Antiarrhythmics: Vardenafil can produce slight QT interval prolongation. Do not take this medication if you have a congenital QT prolongation or take Class IA (e.g., quinidine, procainamide) or Class III (e.g., amiodarone, sotalol) antiarrhythmics.
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Alpha-Blockers (e.g., Tamsulosin, Doxazosin): Co-administration triggers severe additive hypotension and syncope. Alpha-blocker doses must be stable before starting PDE5 inhibitors.
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CYP3A4 Inhibitors: Drugs such as ketoconazole, itraconazole, and ritonavir inhibit hepatic metabolism of both active ingredients, leading to dangerous plasma accumulation.
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Grapefruit & Grapefruit Juice: Grapefruit inhibits intestinal CYP3A4 enzymes, unpredictably increasing blood levels of Vardenafil.
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Alcohol: Avoid alcohol entirely. Combining alcohol with Dapoxetine heightens neurocognitive impairment, increases the risk of syncope (fainting), and counteracts the vascular mechanisms necessary for an erection.
Medical Contraindications
Do not take Extra Super Vilitra if you have:
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Had a myocardial infarction (heart attack) or stroke in the last 6 months.
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Severe heart failure (NYHA Class II-IV), unstable angina, or significant cardiac valvular disease.
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Resting hypotension (BP < 90/50 mmHg) or uncontrolled hypertension.
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Severe hepatic impairment (Child-Pugh Class C) or end-stage renal disease.
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Known hereditary degenerative retinal disorders, such as Retinitis Pigmentosa.
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Under 18 years of age or female.
Storage and Handling
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Store tablets in the original blister foil at room temperature between 15°C and 30°C (59°F to 86°F).
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Keep protected from high humidity, ambient moisture, and direct sunlight.
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Keep safely stored out of reach of children and domestic animals.
Frequently Asked Questions (FAQs)
What makes Extra Super Vilitra different from standard Vilitra?
Standard Vilitra contains only Vardenafil (typically 20 mg) to treat erectile dysfunction. Extra Super Vilitra doubles the Vardenafil dose to 40 mg for severe ED and adds 60 mg of Dapoxetine to simultaneously treat premature ejaculation and provide climax control.
How quickly does Extra Super Vilitra take effect?
The medication should be consumed roughly 45 to 60 minutes before sexual intercourse with a full glass of water.
How long do the effects last?
The therapeutic window for Vardenafil’s erection support lasts approximately 4 to 5 hours, while Dapoxetine’s climax-delaying effect peaks within 2 to 4 hours post-ingestion.
Can I drink alcohol while taking Extra Super Vilitra?
No. Alcohol should be avoided entirely. Combining alcohol with Dapoxetine increases the incidence of severe dizziness, fainting (syncope), and cognitive impairment, while also diminishing the pro-erectile effects of Vardenafil.
References
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National Center for Biotechnology Information (NCBI):
PubChem Compound Summary for CID 110634: Vardenafil. National Library of Medicine.
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National Center for Biotechnology Information (NCBI):
PubChem Compound Summary for CID 71353: Dapoxetine. National Library of Medicine.
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PubMed Central (PMC):
Efficacy and Safety of Dapoxetine in the Treatment of Premature Ejaculation: An Evidence-Based Clinical Review.
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Drugs.com Professional Monograph:
Vardenafil Monograph: Clinical Pharmacology, Interactions, and Dosing Guidelines.










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