Description
About Unigef 250 mg Tablet
Unigef 250 mg Tablet contains gefitinib, a targeted cancer medicine supplied in a pack of 10 tablets to be taken by mouth once daily as prescribed.
How it works
Gefitinib blocks the epidermal growth factor receptor (EGFR), a protein on the surface of cells that passes on signals telling the cell to grow and divide. In lung cancers that carry an activating EGFR mutation, that signal is permanently switched on; gefitinib switches it off, slowing or stopping tumour growth.
What it is used for
Gefitinib is used in the treatment of locally advanced or metastatic non-small cell lung cancer in people whose tumour carries an activating EGFR mutation. A tumour test confirming the mutation is required before treatment, because gefitinib does not work in tumours without it.
Important safety information
Rarely, gefitinib can cause serious inflammation of the lungs. Report any new or worsening breathlessness, cough or fever to your doctor straight away. Skin rash, dry skin, nail changes and diarrhoea are common, and liver enzymes are monitored during treatment. Tell your doctor about any existing lung or liver condition, about eye problems, and about all other medicines you take, including antacids and stomach-acid medicines, which can affect how gefitinib is absorbed.
This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.


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