Amifostine 500 mg · Vial

Ethyfos 500 Mg Injection

Rx (Prescription Medicine)

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Ethyfos 500mg Injection contains amifostine, a cytoprotective agent that helps protect healthy cells from damage caused by chemotherapy and radiation therapy. It is used to reduce side effects like mucositis and nephrotoxicity.

Key facts

Active ingredient
Amifostine
Strength
500 mg
Form
Injection
Drug class
Generic
Brand
Ethyfos
Manufacturer
Zee Laboratories
Pack sizes
1 Vial

Description

Ethyfos 500mg Injection is a medication containing Ethyol (amifostine) as its active ingredient. Amifostine is a cytoprotective agent, meaning it helps protect healthy cells from damage caused by chemotherapy and radiation therapy. It works by being metabolized into a free thiol compound that can scavenge free radicals, which are harmful molecules generated during these treatments. This protective action can help reduce the severity of certain side effects, such as dry mouth and radiation-induced xerostomia (dryness of the mouth), and can also mitigate nephrotoxicity (kidney damage) associated with some chemotherapy drugs like cisplatin.

Ethyfos 500mg Injection is indicated for reducing the incidence of severe thrombocytopenia (low platelet count) and mucositis (inflammation of the mucous membranes) in patients with advanced squamous cell carcinoma of the head and neck cancer receiving radiation therapy, and for reducing the incidence of severe nephrotoxicity in patients with advanced ovarian cancer receiving cisplatin. The dosage and administration should be strictly determined by a qualified healthcare professional based on the patient’s condition and treatment regimen. Common side effects may include nausea, vomiting, dizziness, and transient hypotension (low blood pressure). It is crucial to store Ethyfos 500mg Injection as per the manufacturer’s instructions, typically at room temperature and protected from light.

Additional information

Medicine Form

Injection

Rx Status

Prescription Required

Medicine Type

Allopathy

Molecule

Amifostine

Strength

500mg

Brand Name

Molecule

Strength

500 mg

Medicine Form

Injection

Pack Quantity

1 Vial

Packaging Type

Vial

Medicine Type

Generic

Country Of Origin

India

Rx Status

Rx (Prescription Medicine)

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  1. Key facts
  2. Description
  3. Additional information

Content integrity

Medically reviewed by

Renu Meena, B.Pharm

Medical Content Writer

Renu Meena is an experienced Medical Content Writer with a strong foundation in pharmacy practice. She holds a Bachelor of Pharmacy (B.Pharm) degree from Rajasthan University of Health Sciences (RUHS), Jaipur, and is registered with the Rajasthan State Pharmacy Council (Reg. No. 55661). With 4+ years of experience across clinical pharmacy and medical content development, she creates evidence-based content for medicines, diseases, and patient education. Her work is shaped by a strong understanding of pharmacovigilance and regulatory standards, including ICH guidelines, GVP modules, ICD-10/11, and safety reporting requirements. Renu focuses on making complex medical information simple, accurate, and useful for readers while maintaining high quality and compliance.

Last reviewed 11/08/2026

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