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AVAILABLE MEDICINE FOR Sildenafil Citrate


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Assurans Sildenafil 10mg/12.5ml Injection Assurans Sildenafil 10mg/12.5ml Injection

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Cenforce 100mg Tablets Cenforce 100mg Tablets

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Showing 1 to 20 of 56 (3 Pages)

Sildenafil Citrate, commonly used to treat erectile dysfunction, belongs to a group of molecules known as Phosphodiesterase 5 (PDE 5) inhibitors. It is commonly known by its several brand names such as Viagra, Cenforce and Revatio. 

Beyond its primary use for erectile dysfunction, Sildenafil Citrate is also prescribed for pulmonary arterial hypertension (PAH), where it helps improve blood flow and reduce pressure in the lungs.

Basic Information 

Sildenafil Citrate is the citrate salt form of Sildenafil, a molecule that relaxes blood vessels and enhances blood flow. Below are its key features:

  1. Chemical Structure & Formula: C₂₈H₃₈N₆O₁₁S

  2. Discovered In: The chemical was discovered at Pfizer laboratories in 1989 during research for a chest pain treatment.

  3. FDA approval: The Food and Drug Administration (FDA) approved it as a treatment for ED in March 1998. India’s Central Drugs Standard Control Organisation (CDSCO) approved it for pulmonary arterial hypertension (PAH) in 2007 and for ED in 2013.

  4. Regulatory status: In India, Sildenafil Citrate is a prescription-only medication regulated by the CDSCO and cannot be obtained over the counter.

Uses of Sildenafil Citrate

Sildenafil Citrate helps to treat conditions such as Erectile Dysfunction (ED) and Pulmonary Arterial Hypertension (PAH). 

  1. Erectile Dysfunction (ED)

Erectile dysfunction hampers the ability to get or maintain an erection. Although it is not uncommon to sometimes face this issue, a persistent flaccid penis is a cause for concern. 

If you face any of the below symptoms, consult a doctor:

  • Flaccid penis 

  • Reduced sexual desire

  • Trouble keeping an erection

This drug helps to overcome these symptoms, thus improving your performance and sexual life. Viagra, the first branded formulation by Pfizer, contains Sildenafil Citrate as its active ingredient.

  1. Pulmonary Arterial Hypertension (PAH)

PAH is a condition characterised by high blood pressure between the heart and lungs, affecting the right side of the heart and pulmonary arteries. If you face any of these symptoms, talk to your doctor immediately:

  • Breath shortness while resting

  • Fast pulse

  • Fatigue

  • Blue or gray skin

Sildenafil Citrate helps manage PAH symptoms by improving blood circulation, enhancing heart function, and increasing overall quality of life. Revatio, another branded formulation of Sildenafil Citrate, is specifically used to treat PAH.

Off-Label Uses  of  Sildenafil Citrate

In addition to its approved uses, Sildenafil Citrate is sometimes prescribed for other conditions when alternative treatments are unavailable. These are considered off-label uses, as the drug is not officially authorised for these conditions but may still provide therapeutic benefits.

Sildenafil Citrate is commonly used to treat Secondary Raynaud’s Phenomenon, a condition in which reduced oxygen supply and narrowed blood vessels cause the hands and feet to turn blue. This condition is often associated with underlying health issues such as connective tissue diseases, smoking, carpal tunnel syndrome and blood vessel disorders.

Unlike Primary Raynaud’s Disease, which occurs without an underlying cause, Secondary Raynaud’s Phenomenon is less common and typically develops around the age of 40.

Sildenafil Citrate has been explored as a potential treatment for Female Sexual Arousal Disorder (FSAD) by increasing blood flow to the genital area, potentially improving arousal and sensitivity.

How It Works

Sildenafil Citrate enhances blood flow by targeting cyclic guanosine monophosphate (cGMP), a molecule responsible for smooth muscle relaxation.

Normally, PDE5 enzymes break down cGMP, leading to muscle contraction and restricted blood flow. Sildenafil Citrate inhibits PDE5, allowing cGMP to persist, leading to smooth muscle relaxation and better blood flow to the penis, aiding erection during sexual stimulation.

This mechanism helps maintain an erect penis when sexually stimulated. The same mechanism relaxes the smooth muscles in the lungs, reducing pressure on the heart and improving oxygenation.

Common Side Effects

Sildenafil Citrate causes some common and rare side effects.  Common side effects tend to go away after your body adjusts to the medicine. However, seek a doctor immediately if you face rare side effects. 

Here is a list of common side effects:

  • Nausea 

  • Headaches

  • Flushing 

  • Diarrhea 

  • Bloody nose

  • Warm skin

  • Sneezing 

  • Muscle pain

  • Skin redness

  • Breathing difficulty

  • Pain around eyes and cheekbone

  • Stomach discomfort

  • Stuffy nose

  • Dizziness 

Below are rare symptoms that are associated with sildenafil:

  • Anxiety 

  • Sudden vision loss

  • Chest pain

  • Confusion 

  • Blurred vision

  • Double vision

  • Dry mouth 

  • Dry eyes

  • Behavioural change

  • Excessive hunger 

  • Migraine 

  • Hand numbness 

  • Pain in the joints 

  • Seizures 

  • Skin rash or hives

  • Muscle twitching

  • Shakiness 

  • Sore throat 

There may be other side effects which are not listed here. If you think you are having a side effect as a result of taking sildenafil, contact your doctor immediately. Additionally, if an erection lasts for more than 4 hours and is painful, consult your doctor. 

Avoid Sildenafil if you have underlying heart conditions. Do not take it with nitrate-containing medications, as this can cause a dangerous drop in blood pressure. Inform your doctor about any existing medical conditions or medications before use.

Available Medicines 

Here is a list of companies providing Sildenafil Citrate tablets. 

Brand name

Manufacturer 

Strengths 

Viagra 

Pfizer 

25mg, 50mg,100mg

Cenforce

Centurion Laboratories 

25mg, 50mg, 100mg, 120mg, 130mg, 150mg, 200mg

Endogain-S

Adorefem

25mg

Malegra 

Sunrise Remedies

25mg, 50mg, 100mg, 120mg, 200mg

Suhagra 

Cipla 

25mg, 100mg

Penegra 

Zydus Healthcare 

25mg, 50mg, 100mg, 

Manforce 100

Mankind Pharma

50mg, 100mg, 

Caverta 

Sun Pharmaceuticals

25mg, 50mg, 100mg

Revatio

Pfizer

20mg

Silnafil 

Emcure Pharmaceuticals

25mg

Zenegra 

Alkem Laboratories 

50mg, 100mg

Manly 

Cooper Pharma 

100mg

Vigora 

German Remedies 

25mg, 50mg, 100mg

Femafil 

Ambitree 

100mg

Buy Sildenafil Citrate tablets from Indogenmed and take control of your sexual life again. 

Disclaimer: For information purposes only, it does not replace professional advice. Seek a doctor before consuming Sildenafil Citrate. 

Reference Links:

https://www.drugs.com/history/revatio.html

https://www.webmd.com/drugs/2/drug-7418/sildenafil-oral/details

https://pubmed.ncbi.nlm.nih.gov/16291984/

https://cdscoonline.gov.in/CDSCO/Drugs

https://link.springer.com/chapter/10.1007/978-3-0348-7945-3_1

https://www.medicines.org.uk/emc/ingredient/2366#gref

https://www.adorefem.com/sildenafil-citrate-tablets-brands-in-india/

https://pubchem.ncbi.nlm.nih.gov/compound/Sildenafil-Citrate

https://www.sciencedirect.com/topics/neuroscience/cyclic-guanosine-monophosphate

https://www.ncbi.nlm.nih.gov/books/NBK558978/