Resihance 40 Mg Tablets

Description

About Resihance 40 mg Tablets

Resihance 40 mg Tablets contain regorafenib, a targeted cancer medicine taken by mouth. It is normally taken once daily with a low-fat meal, in cycles of three weeks on and one week off, as prescribed.

How it works

Regorafenib blocks a number of kinases at once. Some, such as VEGFR, control the growth of the new blood vessels a tumour needs; others, such as KIT and RAF, carry growth signals inside the cancer cell itself. Blocking several pathways together limits both the tumour’s blood supply and its growth signalling.

What it is used for

Regorafenib is used in the treatment of metastatic colorectal cancer after previous therapy, gastrointestinal stromal tumours that have progressed on or do not tolerate earlier treatment, and hepatocellular carcinoma (liver cancer) after previous systemic treatment.

Important safety information

Regorafenib can cause serious liver injury, so liver function is tested before and regularly during treatment; report yellowing of the skin or eyes, dark urine or unusual tiredness at once. Redness, pain, blistering or peeling of the palms and soles (hand-foot skin reaction) is common and should be reported early, as the dose can be adjusted. It also raises blood pressure, which is monitored, and can increase the risk of bleeding and affect wound healing, so treatment is paused around surgery. Take it with a low-fat meal as directed, avoid grapefruit, and tell your doctor about all other medicines you take.

This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.