Description
About Sugistran 12.5 mg Capsule
Sugistran 12.5 mg Capsule contains 12.5 mg of sunitinib per capsule, supplied as a pack of 28 capsules. Sunitinib is a targeted anticancer medicine – a multi-kinase inhibitor. Treatment is prescribed and supervised by a cancer specialist.
How it works
Sunitinib blocks a group of enzymes, among them VEGFR, PDGFR and KIT, that tumour cells use to grow and to build the new blood vessels that feed them. Blocking these signals slows the tumour and cuts off part of its blood supply.
What it is used for
Sunitinib is used in advanced renal cell carcinoma, in gastrointestinal stromal tumours where imatinib has stopped working or cannot be tolerated, and in certain pancreatic neuroendocrine tumours.
Important: what this medicine is not
Sunitinib has no role in erectile dysfunction, epilepsy or any neurological condition, and it does not treat raised blood pressure – it can cause it.
Safety and monitoring
Serious liver injury is a recognised risk and liver function is checked before and during treatment – report yellowing of the eyes or skin, dark urine or persistent nausea at once. Tell your doctor about breathlessness, swollen ankles or an irregular heartbeat, any bleeding, and soreness or peeling of the palms and soles. Blood pressure and thyroid function are monitored. The skin may turn yellowish and hair may lose colour; both are expected and reversible.
Prescription and storage
A prescription from your healthcare provider is required to purchase sunitinib. Store at room temperature, away from moisture and direct sunlight, and out of the reach of children.


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