Description
About Sugistran 25 mg Capsule
Sugistran 25 mg Capsule contains 25 mg of sunitinib per capsule, supplied as a pack of 28 capsules. Sunitinib is a targeted anticancer medicine — a multi-kinase inhibitor — prescribed and supervised by a cancer specialist.
How it works
Sunitinib blocks a group of enzymes, among them VEGFR, PDGFR and KIT, that tumour cells use to grow and to build the new blood vessels that feed them. Blocking these signals slows the tumour and cuts off part of its blood supply.
What it is used for
Sunitinib is used in advanced renal cell carcinoma (kidney cancer), in gastrointestinal stromal tumours where imatinib has stopped working or cannot be tolerated, and in certain pancreatic neuroendocrine tumours.
Important: this is a cancer medicine
Sunitinib has no role in erectile dysfunction, and it does not treat pulmonary or any other form of raised blood pressure. Raised blood pressure is in fact one of its side effects, and is monitored during treatment.
Safety and monitoring
Serious liver injury is a recognised risk, and liver function is checked before and during treatment — report yellowing of the eyes or skin, dark urine or persistent nausea and abdominal pain at once. Tell your doctor about breathlessness, swollen ankles or an irregular heartbeat, about any bleeding, and about soreness or peeling of the palms and soles. Thyroid function is monitored, as the thyroid can become underactive. The skin may turn yellowish and hair may lose its colour; both are expected and reversible.
Prescription and storage
A prescription is required, and treatment is given under the supervision of a cancer specialist. Store at room temperature, away from moisture and direct sunlight, and out of the reach of children.


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