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| Brand Name | Imat 400mg |
| Packaging Type | Strip |
| Molecule | Imatinib |
| Generic Name | Imatinib 400mg |
| Manufactured By | Zydus oncosciences |
| Quantity | 10 Tablets |
| Form | Tablet |
| Country of Origin | India |
| Categories | Blood Cancer |
Delivery To:
Delivery in 10 to 15 Business Days*
Introduction to Imat Imatinib 400mg Tablet
Imat Imatinib 400mg Tablets are manufactured by Zydus Oncoscience. They are a targeted cancer therapy approved by the FDA for the treatment of specific cancers. These include chronic myeloid leukemia, acute lymphoblastic leukemia, and gastrointestinal stromal tumors, among others.
The active ingredient, imatinib, is a tyrosine kinase inhibitor. It disrupts abnormal signaling pathways in cancer cells. This effectively halts their growth and spread. Imat is available in the 400mg strength. It is a generic version of the branded drug Gleevec. It offers a cost-effective yet equally potent alternative. Its targeted mechanism makes it suitable for cancers driven by specific genetic mutations. This provides patients with a personalized treatment approach.
Imat 400mg Tablets are designed for optimal absorption and efficacy. They deliver consistent and reliable results in managing cancer. These tablets represent hope for patients with cancers responsive to this therapy. They aid in disease control and improve the quality of life.
How Imatinib Tablet Works?
Imat Imatinib 400mg Tablets are a type of medicine called tyrosine kinase inhibitors. These medicines target specific enzymes that help cells grow, divide, and survive.
In some cancers, genetic changes cause these enzymes, called tyrosine kinases, to become too active. This leads to the uncontrolled growth of cancer cells. The main ingredient in Imat, imatinib, works by blocking these overactive enzymes. It stops them from sending signals that cancer cells need to grow and multiply.
By blocking these signals, Imat slows down the growth of cancer cells and prevents tumors from getting bigger. It also causes cancer cells to die through a process called apoptosis, without harming most normal, healthy cells. This precise way of working makes Imat effective for certain cancers caused by specific genetic mutations.
Uses of Imat Imatinib 400mg Tablets
Imat 400mg Tablets are indicated for the treatment of several cancers and conditions, including:
- Imatinib blocks the BCR-ABL tyrosine kinase enzyme, which is responsible for cancer cell growth in CML.
- Specifically effective for Philadelphia chromosome-positive (Ph+) ALL, a subtype of leukemia. It interrupts the signaling pathways that promote the uncontrolled growth of cancer cells.
- Imatinib inhibits the proteins responsible for tumor growth, slowing or stopping its progression.
- It targets and regulates genetic abnormalities causing these disorders.
- Imatinib helps normalize eosinophil levels by targeting abnormal signaling pathways.
- It blocks PDGF receptor pathways involved in tumor growth, preventing further progression.
Dosage and Administration
Standard Dosage
- The recommended dose for most conditions is 400mg once daily. In some cases, the dose may be increased to 600mg or 800mg daily based on the patient’s response and medical condition.
How to Take
- Swallow the tablet whole with a glass of water. Take it with food to reduce the risk of stomach upset.
Missed Dose
- If you forget to take a dose, take it as soon as you remember. If it’s close to your next dose, skip the missed dose and continue as scheduled. Do not double the dose.
- Continue taking the medication as advised by your doctor. Do not stop treatment unless instructed by your healthcare provider.
Side Effects of Imat Imatinib 400mg Tablets
Like all medications, Imat 400mg Tablets may cause side effects. While many side effects are mild and temporary, it’s important to monitor your health and report any concerns to your doctor.
Common Side Effects
- Swelling
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Muscle cramps
- Fatigue
- Dizziness
- Skin rash
- Increased weight
- Decreased red or white blood cell counts
Serious Side Effects
- Liver problems
- Heart issues
- Gastrointestinal bleeding
- Low blood cell counts lead to anemia
- If you experience severe side effects, such as difficulty breathing, chest pain, or symptoms of liver issues, contact your doctor immediately
Precautions and Warnings
PregnancyImat 400mg Tablets are not safe during pregnancy. Women of childbearing potential should use effective contraception during treatment and for 15 days after the last dose.
BreastfeedingNot recommended as the medication can pass into breast milk and harm the baby.
Driving and machineryAvoid driving or operating machinery if you experience dizziness, drowsiness, or blurred vision.
Liver and Kidney DisordersUse cautiously if you have liver or kidney conditions. Regular monitoring and dose adjustments may be necessary.
InfectionsInform your doctor if you develop fever, fatigue, or unusual bruising, as the medication may lower your immune response.
Drug Interactions
Imat 400mg Tablets may interact with other medications, reducing their efficacy or increasing the risk of side effects. Inform your healthcare provider about all the medicines you are taking, including:
- Antibiotics
- Antifungal medications
- Blood thinners
- Medications for seizures
- Herbal supplements
Why Choose Imat Imatinib 400mg Tablets?
Imat 400mg Tablets are a trusted choice for targeted cancer therapy, offering proven efficacy in treating various cancers with minimal impact on healthy cells. Manufactured to the highest standards, this medication provides hope and relief to patients battling complex cancers. Choose Imat 400mg Tablets for effective, reliable cancer treatment.
| Criteria | Imat Imatinib 400mg Tablet | Gleevec Imatinib 400mg Tablet |
| Active Ingredients | Imatinib | Imatinib |
| Manufacturer | Zydus Oncoscience | Novartis |
| Primary use | Treatment of CML, GST, and other cancer | Treatment of CML, GST, and other cancer |
| Key difference | Generic version of Gleevec, typically more affordable | Branded often, more expensive |
| Side effect | Fatigue, nausea, edema etc | Same as generic, including heart failure, liver issues |
| Cost | $75 (apx) | $30(apx) |
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