| Brand Name | Osimert |
| Packaging Type | Bottle |
| Molecule | Osimertinib |
| Generic Name | Osimertinib 80mg |
| Manufactured By | Everest Pharmaceuticals |
| Quantity | 30 Tablets |
| Form | Tablet |
| Country of Origin | Bangladesh |
| Categories | Oncology |
Description
Overview of Osimert 80mg
Osimert 80mg, manufactured by Everest Pharmaceuticals, is a popular prescription medicine for treating non-small cell lung cancer (NSCLC). This medicine's active ingredient is Osimertinib, which blocks the EGFR protein, the main driver of cancer cell growth. By blocking this protein, Osimertinib helps to slow tumour progression and alleviate symptoms such as coughing and difficulty breathing.
Osimert 80mg is typically taken as a single, whole tablet once a day. One of its key advantages is that it tends to cause fewer side effects than traditional chemotherapy. Proper medical supervision is necessary before taking this medicine.
Key Benefits of Osimert 80
Here are some common distinguishing benefits of Osimert 80mg:
Osimert 80mg particularly targets EGFR mutations that are responsible for the growth of cancer cells. This kind of focused intervention disrupts the process and hinders cancer progression at its core.
Osimert 80mg is especially beneficial for patients who have developed resistance to first-generation EGFR inhibitors. This medicine is not only used as an effective treatment option but also serves as a line of defence against cancer.
Based on clinical evidence, Osimert 80mg by Everest Pharma is associated with improved progression-free survival in patients with advanced NSCLC. By slowing tumour growth, it offers hope for extending life and alleviating disease progression, improving patients' overall prognosis.
Unlike traditional chemotherapy, Osimert 80mg primarily targets cancer cells, minimizing harm to healthy, normal cells. This selective action reduces side effects and helps enhance the body’s tolerance to the medication, making the treatment more manageable for patients.
How Does Osimert 80 Work?
Osimert 80mg, commonly known as Tagrisso Generic, is a powerful medicine for treating lung cancer. It works well by blocking the EGFR protein, which is the root cause of cancer cells growing. This protein component keeps changing among lung cancer patients, and thus, the disease becomes difficult and challenging to cure. In many lung cancer patients, the EGFR gene undergoes mutations, allowing cancer cells to grow uncontrollably.
It also reduces tumour growth, improving breathing and coughing over time. Before taking this medicine, patients should follow their doctors' instructions carefully.
For individuals with pre-existing lung or heart conditions, it is crucial to monitor these aspects regularly while using Osimert 80mg, as the medication may have some impact on these organs. When used correctly, Osimert 80mg can provide significant relief and improve patients' quality of life, helping them manage the disease and live longer.
Dosage and Administration of Osimert 80
Here is how Osimert should be administered:
The recommended dosage of Osimert 80mg by Everest Pharma is once daily until disease progression occurs or if unacceptable toxicity is observed.
Individuals can take this medicine both with and without food.
If you miss a dose of Osimertinib, do not take the missed dose; instead, take the next dose as scheduled.
If there is difficulty swallowing solids, the Osimert 80mg tablet should be dissolved in only four tablespoons of noncarbonated water. Continue stirring until completely dispersed, then immediately swallow it through a nasogastric tube.
Do not heat, crush, or ultrasonicate during preparation.
Strengths and Substitutes of Osimert 80
Osimert 80mg helps to treat non-small cell lung cancer (NSCLC) with EGFR mutations. It primarily targets cancer cells, slows tumour growth, and improves patient survival. It has fewer side effects than traditional chemotherapy, making it suitable and convenient for patients. There is only one strength of Osimert: 80mg.
Strength | Alternative Forms |
80 mg | Take the tablet by mouth once a day. |
The most popular substitute for Osimert 80mg is Tagrisso 80mg. Both medications contain the same active ingredients, but Tagrisso is a popular brand name manufactured by AstraZeneca. However, there are quite a few more substitute medications available:
Ositab 80mg Tablet
Irmukin 80mg Tablets
Tasso 80mg Tablets
Osimatab 80mg Tablet
Osikin 80mg Tablets
Osicent Osimertinib 80mg Tablets
Osinib 80mg Tablets
Tasso 80mg Tablets
Osmigen 80mg Tablets
Side Effects of Osimert 80
Some of the common side effects of Osimert 80mg include the following:
Diarrhea
Tired feeling
Loss of appetite
Mouth sores
Dry skin
Rash
Discolouration
Pain
Infection
Problems with fingernails or toenails
Some other more serious side effects include:
Shortness of breath with mild exertion
The feeling of lightheadedness, you might pass out
Fast heartbeat
Swelling
Fast weight gain
Worsening of lung symptoms such as discomfort, chest pain, dry cough, wheezing, shortness of breath, and others
Eye problems – changes in vision, watery eyes, eye pain, redness, increased sensitivity to light.
Safety and Precautions of Osimert 80
Osimert 80 is one of the popular and targeted treatments used for treating non-small cell lung cancer (NSCLC) with specific genetic mutations. Given its effectiveness, it needs close monitoring due to potential side effects.
Patients should follow medical guidance and undergo regular check-ups to ensure safety. Let us explore the safety and precautions of Osimert 80 in detail below:
Interstitial Lung Disease (ILD): Commonly known as pneumonia, patients diagnosed with this disease should permanently discontinue this medicine.
Cardiomyopathy: Before starting Osimert 80mg, a patient’s left ventricular ejection fraction (LVEF) should be assessed. Regular monitoring of LVEF should continue every 3 months during treatment to detect any potential signs of cardiomyopathy.
QTc Interval Prolongation: Patients with a history of QTc prolongation or those taking medicines that prolong the QTc interval should undergo daily electrolyte monitoring and electrocardiogram monitoring. If significant QTc prolongation is observed, Osimert 80mg may need to be withheld and later reintroduced at a reduced dose, or permanently discontinued.
Keratitis: Patients should inform their healthcare provider immediately if they have this eye disease and experience symptoms such as lacrimation, eye inflammation, eye pain, light sensitivity, redness, or vision changes.
Embryo Fetal Toxicity: Osimert 80mg can cause significant harm to a developing fetus, making it unsafe for pregnant women. Females of childbearing potential should use effective contraception during treatment with Osimert and continue for 6 weeks after the last dose. On the other hand, males should use effective contraception for 4 months after the final dose to prevent potential exposure to the drug through semen.
Consult with your doctor to see if Osimert 80mg is suitable for you. Make sure to follow the medical advice carefully and do not start taking the medicine without consulting a healthcare professional.