Afatin 20mg Tablet is a targeted therapy medication used in the treatment of certain types of non-small cell lung cancer (NSCLC) that have specific genetic mutations. The active ingredient, Afatinib, is a tyrosine kinase inhibitor (TKI) that works by blocking the signals that cancer cells need to grow and divide. It specifically targets the epidermal growth factor receptor (EGFR) pathway, which is often overactive in certain lung cancers.
Afatinib is indicated for patients with metastatic NSCLC whose tumors have specific EGFR mutations (exon 19 deletions or exon 21 (L858R) substitution mutations) as detected by an FDA-approved test. It is typically used as a first-line treatment for these patients.
The recommended dosage is usually 40mg once daily. However, dosage adjustments may be made by a healthcare professional based on individual response and tolerance. It is important to take Afatin 20mg Tablet exactly as prescribed by your doctor, with or without food. Do not crush or chew the tablets.
Common side effects may include diarrhea, rash, acneiform dermatitis, stomatitis, and decreased appetite. Serious side effects can occur, and patients should report any new or worsening symptoms to their doctor immediately. Afatin 20mg Tablet should be stored at room temperature, away from moisture and heat.
