Description
About Afayro 40 mg Tablet
Afayro 40 mg Tablet contains 40 mg of afatinib per tablet, supplied as a pack of 28 tablets. Afatinib is a targeted anticancer medicine – an irreversible tyrosine kinase inhibitor of the ErbB family. Treatment is prescribed and supervised by a cancer specialist.
How it works
Some lung cancers grow because of a fault in a cell-surface receptor called EGFR, which becomes stuck in the “on” position and drives the cell to keep dividing. Afatinib binds irreversibly to that receptor and to its relatives HER2 and HER4, blocking the growth signal they send into the cell.
What it is used for
Afatinib is used in non-small cell lung cancer that has spread, where testing has shown the tumour carries an activating EGFR mutation, and in certain squamous non-small cell lung cancers that have progressed after platinum-based chemotherapy. Testing of the tumour decides whether it is suitable.
Important: what this medicine is not
Afatinib is not a skin treatment, an antibiotic or a blood pressure medicine. An acne-like rash is a common side effect of afatinib, not something it treats.
Safety and monitoring
Diarrhoea is the most common serious effect and can begin early; it can lead to dehydration and kidney problems if untreated, so report it rather than waiting. An acne-like rash is common and skin becomes more sensitive to sunlight. Tell your doctor about new or worsening breathlessness or cough, which may need investigation for inflammation in the lungs, and about eye pain, redness or changes in vision. Liver function is monitored.
Prescription and storage
A prescription from your healthcare provider is required to purchase afatinib. Store at room temperature, away from moisture and direct sunlight, and out of the reach of children.
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