Description
About Assurans Injection
Assurans Injection contains 10 mg of sildenafil citrate per vial. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, and at this strength and in this form it is used for pulmonary arterial hypertension.
How it works
PDE5 is the enzyme that breaks down cyclic GMP, the signal that keeps blood vessels relaxed. By blocking it, sildenafil allows cyclic GMP to persist in the arteries supplying the lungs, so those vessels stay wider and the pressure within them falls. That reduces the load on the right side of the heart.
What it is used for
Sildenafil in this form is used for pulmonary arterial hypertension, for patients who are temporarily unable to take the oral tablets. This is raised pressure in the lung arteries — a different condition from ordinary high blood pressure, and not treated with the medicines used for that.
Important: medicines it must not be combined with
Sildenafil must not be used with nitrates or other nitric oxide donors, nor with riociguat, because the combination can cause a dangerous fall in blood pressure. Tell your doctor every medicine you take.
Safety and monitoring
This medicine is given by a doctor or nurse and is not self-administered. Headache, flushing, indigestion and nasal congestion are common. Tell your doctor about sudden changes in vision or hearing, and about an erection lasting more than four hours, which needs urgent medical attention. Suitability depends on your diagnosis, your heart and liver function and your other medicines.
Prescription and storage
A prescription from your healthcare provider is required. Store as directed on the pack, away from direct sunlight, and out of the reach of children.
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