Description
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Caverta 100 Mg Tablets
Caverta 100 Mg Tablets contain sildenafil citrate 100 mg, a phosphodiesterase type 5 (PDE5) inhibitor manufactured by Ranbaxy Laboratories (now Sun Pharmaceutical Industries). Caverta is one of the established generic sildenafil formulations used for the treatment of erectile dysfunction (ED) in adult men. It has the same active ingredient, mechanism, and clinical profile as the originator medicine Viagra.
Composition
| Active Ingredient | Strength |
|---|---|
| Sildenafil Citrate | 100 mg per tablet |
About the Manufacturer
Caverta is manufactured by Ranbaxy Laboratories, which is now a part of Sun Pharmaceutical Industries Limited — one of the world’s leading specialty generic pharmaceutical companies, headquartered in Mumbai, India. Ranbaxy was one of the first manufacturers to market generic sildenafil internationally, and Caverta is among its best-known branded generic formulations for erectile dysfunction.
Mechanism of Action
Sildenafil is a selective inhibitor of PDE5, the enzyme that degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle of the corpus cavernosum. During sexual stimulation, nitric oxide activates guanylate cyclase, raising cGMP levels, which relaxes penile smooth muscle and increases blood flow into the corpus cavernosum, producing an erection. By preventing cGMP degradation, sildenafil prolongs and enhances this physiological erectile response. The drug does not produce erection without sexual stimulation.
Indications
- Erectile dysfunction (ED) in adult men — inability to achieve or maintain a satisfactory erection for sexual intercourse
Dosage & Administration
- Swallow tablet whole with water
- Take approximately 30–60 minutes before anticipated sexual activity
- High-fat meals can delay onset of effect — take on an empty stomach or at least 2 hours after a large meal for fastest action
- Standard starting dose: 50 mg; this 100 mg tablet is for men who have not had sufficient response to 50 mg
- Maximum dose: 100 mg once per 24 hours
- Effective window: typically 4–6 hours
Special Populations
- Elderly (>65 years): Start at 25 mg due to reduced clearance
- Severe renal impairment (CrCl <30 mL/min): Starting dose of 25 mg recommended
- Hepatic impairment: Starting dose of 25 mg; maximum 50 mg
- Children: Not indicated
- Women: Not indicated for ED
Precautions
- Cardiovascular risk: ED is a marker of cardiovascular disease; assess cardiac fitness before initiating treatment
- Nitrates: combination with nitrates in any form is absolutely contraindicated — severe, potentially fatal hypotension
- Hypotension: sildenafil causes modest BP reduction; use with caution in patients on antihypertensives or with low BP
- Vision: seek immediate medical attention for sudden vision loss in one or both eyes
- Priapism: erections lasting longer than 4 hours require urgent medical attention to prevent permanent damage
- Colour vision: transient blue-green visual tinge may occur; caution in patients with retinitis pigmentosa
Contraindications
- Concurrent use of nitrates in any form (absolutely contraindicated)
- Concurrent use of nitric oxide donors (amyl nitrite / “poppers”)
- Hypersensitivity to sildenafil or any excipient
- Recent stroke or myocardial infarction
- Serious cardiovascular conditions where sexual activity is inadvisable
- Hereditary degenerative retinal disorders (retinitis pigmentosa)
Side Effects
- Very common: Headache, flushing, dyspepsia
- Common: Nasal congestion, dizziness, visual disturbances (blurred vision, blue-green colour tinge), nausea
- Less common: Palpitations, hypotension, back pain, myalgia, rash
- Rare: Priapism, non-arteritic ischaemic optic neuropathy (NAION), sudden hearing loss, severe cardiovascular events
Drug Interactions
- Nitrates (all forms): Absolutely contraindicated — severe, potentially fatal hypotension
- Alpha-blockers: Additive hypotension; begin at 25 mg if established on an alpha-blocker
- CYP3A4 inhibitors (ritonavir, ketoconazole, itraconazole, erythromycin, grapefruit juice): Increase sildenafil plasma levels significantly; maximum 25 mg per 48 hours with ritonavir
- CYP3A4/CYP2C9 inducers (rifampicin): May significantly reduce sildenafil efficacy
- Other PDE5 inhibitors: Do not combine
- Antihypertensives: Enhanced blood-pressure-lowering effect
Storage
Store below 30°C in a dry place, protected from light and moisture. Keep tablets in the original blister packaging. Keep out of reach of children. Do not use after the expiry date printed on the pack.
Related Products
- Manly 100 Mg Tablets – sildenafil 100 mg for ED
- Erex 50 Mg Tablets – sildenafil 50 mg for ED
- Sildisoft 100 Mg Chewable Tablet – sildenafil 100 mg chewable formulation
- Tazzle 20 Mg Tablets – tadalafil 20 mg alternative PDE5 inhibitor
Frequently Asked Questions
- What is Caverta 100 Mg and what is it used for?
- Caverta 100 Mg is a branded generic sildenafil tablet used to treat erectile dysfunction (ED) in adult men. It contains 100 mg of sildenafil citrate — the same active ingredient as Viagra — and works by increasing blood flow to the penis when a man is sexually stimulated.
- How is Caverta different from Viagra?
- Caverta and Viagra contain the same active ingredient — sildenafil citrate — and work in the same way. The difference is that Caverta is a branded generic manufactured by Ranbaxy/Sun Pharma, typically offered at a lower price than the originator. The clinical effects, onset, duration, and safety profile are the same.
- How long does Caverta 100 Mg take to work?
- Caverta typically begins working within 30–60 minutes of taking the tablet, and its effect lasts approximately 4–6 hours. Taking it on an empty stomach or at least 2 hours after a light meal can speed up the onset of action, as a high-fat meal may delay absorption.
- What is the maximum dose of Caverta I should take?
- The maximum recommended dose is 100 mg once every 24 hours. Many men find that 50 mg is effective, and older patients or those with kidney or liver conditions may need to start at 25 mg. Never exceed 100 mg in one day, and always follow your doctor’s specific instructions.
- Is it safe to take Caverta if I am on blood pressure medicines?
- Sildenafil can be used by some men on blood pressure medicines, but it has additive blood-pressure-lowering effects and must never be combined with nitrate medicines (commonly used for chest pain / angina). Taking it with alpha-blocker medicines for blood pressure or prostate conditions also requires caution. Always tell your doctor about all medications you take before starting Caverta.
References
- NHS – Sildenafil (Viagra)
- MedlinePlus – Sildenafil
- FDA – Viagra (Sildenafil) Prescribing Information
- EMA – Viagra (Sildenafil) EPAR
Disclaimer: This page is for informational purposes only and does not constitute medical advice. Caverta 100 Mg Tablets must be used under the supervision of a qualified healthcare professional. Never combine sildenafil with nitrates in any form. Seek immediate medical attention for chest pain, sudden vision loss, or a prolonged erection lasting more than 4 hours.
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