Description
About Comfora 100 mg Capsules
Comfora 100 mg Capsules contain pentosan polysulfate sodium, supplied in a pack of 30 capsules. They are taken by mouth with water, at least one hour before or two hours after food, as prescribed.
How it works
The inside of the bladder is lined with a protective layer of glycosaminoglycans that keeps irritating substances in urine away from the bladder wall. In interstitial cystitis this layer is thought to be defective. Pentosan polysulfate is a similar molecule that is taken up into the bladder lining, where it is believed to help restore that barrier.
What it is used for
Pentosan polysulfate sodium is used to relieve the bladder pain and discomfort of interstitial cystitis, also called bladder pain syndrome. It treats the symptoms rather than an infection, and it is not an antibiotic or a painkiller. Benefit builds slowly and may take two to six months to become apparent, so treatment is reviewed rather than judged in the first few weeks.
Important safety information
Changes to the retina at the back of the eye have been reported with long-term use. Tell your doctor about any change in vision, difficulty reading, or trouble adjusting to dim light, and attend any eye checks you are offered. Pentosan polysulfate has a mild blood-thinning effect, so tell your doctor if you take anticoagulants or aspirin, or have a bleeding disorder, and before any surgery or dental work. Nausea, diarrhoea, headache and hair thinning are reported. Tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.


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The standard of medicine, lowest prices, and but my parcel was delivered late, overall Excellent service