Nuparp 200 Mg Tablet

Description

About Nuparp 200 mg Tablet

Nuparp 200 mg Tablet contains rucaparib, a targeted cancer medicine of the PARP inhibitor class, supplied in a pack of 60 tablets to be taken by mouth.

How it works

PARP is an enzyme cells use to repair single-strand breaks in their DNA. Rucaparib blocks PARP. In cancer cells that already have a faulty DNA repair pathway, such as those with a BRCA mutation, losing PARP as well means the damage cannot be repaired and the cell dies, while normal cells with intact repair are better able to cope.

What it is used for

Rucaparib is used in the treatment of ovarian, fallopian tube and primary peritoneal cancer, including as maintenance treatment after platinum-based chemotherapy, and in certain cases of metastatic castration-resistant prostate cancer. Genetic or tumour testing is usually required to decide whether it is appropriate.

Important safety information

Rucaparib can lower blood cell counts, so regular blood tests are needed; tell your doctor about unusual tiredness, breathlessness, fever or bruising. Rarely, serious bone-marrow disorders have been reported with this class of medicine. Nausea, tiredness, taste changes and raised liver enzymes are common. It can harm an unborn baby, and effective contraception is required. Tell your doctor about all other medicines you take and about any liver or kidney problems.

This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.