Tentide Em Tablets

Description

About Tentide EM Tablet

Tentide EM Tablet is manufactured by Sun Pharmaceutical Industries in India and is a fixed-dose combination containing tenofovir disoproxil fumarate in one tablet, supplied as a strip of 30. It is taken by mouth once daily.

How it works

Both ingredients are nucleoside or nucleotide reverse transcriptase inhibitors. HIV needs the enzyme reverse transcriptase to turn its genetic material into DNA that can be inserted into a human cell. These two medicines resemble the building blocks that the enzyme uses, and when it takes them up instead, the chain cannot be completed and the virus cannot replicate. Two agents are combined because using more than one pathway makes resistance far less likely.

What it is used for

This combination is used as part of antiretroviral therapy in the treatment of HIV-1 infection, normally alongside a third agent, and also for pre-exposure prophylaxis (PrEP) in people at substantial risk of acquiring HIV.

Important safety information

For PrEP, HIV-negative status must be confirmed before starting and re-tested regularly; taking this combination alone while HIV is present can cause resistance. Both ingredients are also active against hepatitis B, so hepatitis B status should be known before starting, and stopping treatment can trigger a severe flare.

Tenofovir disoproxil can affect the kidneys and reduce bone mineral density, so kidney function is monitored. Take it every day without missing doses. Tell your doctor about all other medicines, particularly anything affecting the kidneys.

This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.