Chemotinib 400 Mg Tablet

Description

About Chemotinib 400 mg Tablet

Chemotinib 400 mg Tablet contains imatinib, a targeted cancer medicine taken by mouth, usually once daily with food and a large glass of water.

How it works

Imatinib blocks specific tyrosine kinases, in particular the abnormal BCR-ABL protein produced by the Philadelphia chromosome, and the KIT and PDGFR proteins. These act as permanently switched-on growth signals in certain cancers; imatinib switches them off, so the cancer cells stop multiplying.

What it is used for

Imatinib is used in the treatment of Philadelphia chromosome-positive chronic myeloid leukaemia and acute lymphoblastic leukaemia, gastrointestinal stromal tumours (GIST), and several rarer blood and soft-tissue disorders driven by the same signalling proteins.

Important safety information

Fluid retention, showing as puffiness around the eyes, swollen ankles or sudden weight gain, is common and should be reported. Imatinib lowers blood counts and can affect the liver, so blood tests are taken regularly. Nausea, muscle cramps, rash and tiredness are common. Take it with food to reduce stomach upset, and avoid grapefruit. Tell your doctor about all other medicines, including paracetamol and herbal products, and about any heart, liver or kidney problems.

This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.