Description
About Herhope 440 mg Injection
Herhope 440 mg Injection contains trastuzumab, a monoclonal antibody, supplied as a multi-dose vial of powder that is reconstituted and given as an intravenous infusion by trained healthcare staff.
How it works
Some cancers make too much of a protein called HER2 on the surface of their cells, which drives the cells to grow and divide. Trastuzumab attaches to HER2 and blocks that growth signal, and also flags the cell so that the body’s own immune cells can attack it.
What it is used for
Trastuzumab is used in the treatment of HER2-positive breast cancer, in both early and advanced disease, and in HER2-positive metastatic cancer of the stomach and gastro-oesophageal junction. It is often given alongside chemotherapy. HER2 status must be confirmed by a validated test before treatment begins.
Important safety information
Trastuzumab can reduce the heart’s pumping function, so heart function is assessed before treatment and monitored during it; the risk is higher when it is given with or after anthracycline chemotherapy. Infusion-related reactions and, uncommonly, lung problems can occur, so the first infusions are given with close observation. It can harm an unborn baby and effective contraception is required. Tell your doctor about any heart or lung condition and all other medicines you take.
This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.
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