Endobloc 10 Mg Tablets

Description

About Endobloc 10 mg Tablets

Endobloc 10 mg Tablets contain 10 mg of Ambrisentan per tablet, supplied as a pack of 10 tablets. Ambrisentan is an endothelin receptor antagonist.

How it works

The lining of the lung arteries produces endothelin, a substance that makes those vessels narrow and thicken. Ambrisentan blocks the endothelin-A receptor it acts on, so the arteries stay wider and the right side of the heart works against less resistance.

What it is used for

Ambrisentan is used in pulmonary arterial hypertension, to improve exercise capacity and slow the worsening of the condition. This is a different condition from ordinary high blood pressure: it affects the arteries carrying blood from the heart to the lungs, and it is not treated with the medicines used for systemic hypertension. Ambrisentan is not interchangeable with those medicines.

Important: it must not be used in pregnancy

Medicines of this class can seriously harm a developing baby. Pregnancy is excluded before treatment starts, and reliable contraception is required throughout and for a period afterwards, with regular pregnancy testing. Tell your doctor at once if you think you may have become pregnant.

Safety and monitoring

Fluid retention and swelling of the legs and ankles are common, and anaemia can develop, so a blood count is checked during treatment. Ambrisentan is not suitable for people with pulmonary hypertension caused by idiopathic pulmonary fibrosis. Tell your doctor about increasing breathlessness, swelling of the ankles or legs, unusual tiredness or a rapid weight gain, which can mean fluid is building up. Mention every other medicine you take.

Prescription and storage

A prescription from your healthcare provider is required to purchase Ambrisentan. Store the tablets at room temperature, away from moisture and direct sunlight, and out of the reach of children.