Temorel 250 Mg Capsule

Description

About Temorel 250 mg Capsule

Temorel 250 mg Capsule contains 250 mg of temozolomide per capsule, supplied as a pack of 100 capsules. Temozolomide is a cytotoxic chemotherapy medicine of the alkylating agent class, taken by mouth. Treatment is prescribed and supervised by a cancer specialist.

How it works

Temozolomide converts in the body into a reactive compound that attaches a methyl group to the DNA of dividing cells. The cell cannot repair that change, so it stops dividing and dies. It crosses into the brain, which is why it is used for tumours there.

What it is used for

Temozolomide is used in glioblastoma, alongside and after radiotherapy, and in anaplastic astrocytoma that has returned or progressed after other treatment.

Important: what this medicine is not

Temozolomide is not an antibiotic and is not a medicine for epilepsy. It treats tumours of the brain; it does not treat seizures, although people with brain tumours may be prescribed separate medicines for those.

Safety and monitoring

Blood counts fall, particularly platelets, and are checked before each cycle – report fever, bruising or bleeding. While it is given with radiotherapy an antibiotic is usually added to prevent a specific chest infection. Nausea and vomiting are common and anti-sickness medicine is given beforehand. Capsules are swallowed whole, never opened, and the timing in relation to food follows the instructions you are given. Tiredness and constipation are frequent.

Prescription and storage

A prescription from your healthcare provider is required to purchase temozolomide. Store at room temperature, away from moisture and direct sunlight, and out of the reach of children.