Description
About Zyceva 150 mg Tablets
Zyceva 150 mg Tablets contain erlotinib, a targeted cancer medicine taken by mouth once daily. It should be taken at least one hour before, or two hours after, food.
How it works
Erlotinib blocks the epidermal growth factor receptor (EGFR), a protein on the cell surface that signals the cell to grow and divide. In lung cancers carrying an activating EGFR mutation that signal is permanently switched on; erlotinib switches it off, slowing or halting tumour growth.
What it is used for
Erlotinib is used in the treatment of locally advanced or metastatic non-small cell lung cancer in people whose tumour carries an activating EGFR mutation, and in advanced pancreatic cancer in combination with gemcitabine. A tumour test is required before treatment for the lung cancer indication.
Important safety information
An acne-like rash and diarrhoea are the most common side effects and are often manageable with supportive treatment; tell your doctor rather than stopping the medicine yourself. Rarely, erlotinib can cause serious inflammation of the lungs, so any new or worsening breathlessness or cough should be reported immediately. Liver function is monitored. Smoking reduces the amount of erlotinib in the blood. Avoid grapefruit, and tell your doctor about all other medicines including stomach-acid medicines and warfarin.
This is a prescription-only medicine. It should be used only under the supervision of a qualified healthcare professional, who will decide whether it is suitable for you and at what dose.
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