Hisone 20 Mg Tablets

Description

Hisone 20 mg Tablets (Hydrocortisone 20 mg)

Hisone 20 mg Tablets contains hydrocortisone 20 mg, a corticosteroid hormone used for two broad purposes: replacing the natural cortisol the body does not make enough of, and reducing inflammation in a range of conditions. It is manufactured in India and supplied as a prescription medicine. Hisone is available in several strengths, and this product is the 20 mg tablet. It should be taken only under medical supervision.

Composition

Product Details

Hisone 20 is a 20 mg hydrocortisone tablet, sold in strips of 10 tablets in most Indian presentations. The lower Hisone strengths, 5 mg and 10 mg, are used when a smaller dose is needed. Because the tablet strength determines the dose, always check the number of tablets against the prescription. Pack details may vary between suppliers.

Mechanism of Action

Hydrocortisone is a naturally occurring glucocorticoid. It binds to intracellular glucocorticoid receptors and changes the expression of many genes, which reduces the production of inflammatory mediators and suppresses immune responses. It also acts as a replacement for cortisol, the hormone the adrenal glands make, which is needed for stress response, blood pressure, blood sugar and metabolism.

Indications

Hisone 20 is used as a replacement therapy in adrenal insufficiency, where the body does not make enough cortisol. It is also used for inflammatory and allergic conditions such as arthritis, certain skin disorders, allergic reactions and some bowel inflammation. The doctor decides the dose and duration based on the condition being treated. The initial dose may range widely, depending on the disease being treated.

Dosage and Administration

Take the tablet exactly as prescribed, usually in divided doses through the day for inflammatory conditions and as a once-daily or split dose for hormone replacement. Take the tablets with food to reduce stomach upset. Do not stop suddenly after long-term use, because the body may not restore its own cortisol production quickly and withdrawal can be dangerous. When the dose is reduced, the doctor will taper it gradually. Carry a steroid alert card if you are on long-term treatment, and tell any doctor or dentist who treats you that you take this medicine.

Special Populations

Children: Long-term corticosteroid therapy can slow growth and development in children, so paediatric use should be monitored closely by a specialist.

Pregnancy and breastfeeding: The effect of this medicine during pregnancy and while breastfeeding should be weighed by the doctor against the benefit. Tell the doctor about any pregnancy before starting.

Older adults: Older patients are more prone to bone thinning, high blood sugar, high blood pressure and infections while on steroids, so their treatment is monitored more closely.

Precautions

Hydrocortisone lowers the body’s ability to fight infection. Avoid contact with people who have measles or chickenpox, and tell your doctor at once if you develop a fever, cough or any new infection. Avoid excess salt, since steroids can cause fluid retention and raise blood pressure. Diabetes, high blood pressure, heart failure, stomach ulcers, osteoporosis, glaucoma and mental health conditions can all be affected, so tell your doctor about them before starting. Do not stop the tablets abruptly, and do not skip doses during illness or surgery without medical advice.

Contraindications

Do not use Hisone 20 if you are allergic to hydrocortisone or to any ingredient in the tablet. Do not use it for an untreated systemic fungal infection. Use only with specialist guidance in active tuberculosis or other serious infections.

Side Effects

Common effects include increased appetite, weight gain, fluid retention, ankle swelling, headache, dizziness, insomnia and mood changes. Long-term use can cause raised blood sugar, high blood pressure, thinning bones, muscle weakness, stomach irritation and an increased risk of infection. Seek urgent medical help for signs of infection, black or bloody stools, severe abdominal pain, vision changes, or a sudden drop in energy with dizziness or vomiting, which can signal adrenal crisis.

Drug Interactions

Hydrocortisone can interact with blood thinners such as warfarin, with diabetes medicines, with diuretics that lower potassium, and with some vaccines. Mifepristone can reduce the effect of hydrocortisone, and natalizumab can increase the risk of infection when combined with it. Non-steroidal anti-inflammatory drugs taken together with steroids raise the risk of stomach bleeding. Tell your doctor about every medicine you take, including over-the-counter and herbal products.

Storage

Store the tablets at room temperature, away from moisture, heat and direct sunlight, in the original pack. Keep them out of the reach of children and pets, and do not use tablets if the packaging is damaged or the tablets look discoloured.

Frequently Asked Questions

Can I stop Hisone once my symptoms improve?
No. Stopping suddenly can cause withdrawal symptoms and adrenal crisis. The doctor will reduce the dose slowly.

Should I take it with food?
Yes. Taking the tablet with food helps reduce stomach discomfort.

Can I take this medicine with a vaccine?
Tell your doctor before any vaccination, because steroids can affect how vaccines work and some vaccines are not suitable while on steroid treatment.

What should I do if I miss a dose?
Take it as soon as you remember unless it is almost time for the next dose. Do not take two doses together.

References

• GNH India, Hisone 20 (Hydrocortisone USP 20 mg tablet) product information: https://www.gnhindia.com/products/hisone-20-tablet
• Apollo Pharmacy, Hisone-20 Tablet product information (hydrocortisone 20 mg, interactions with mifepristone and natalizumab): https://www.apollopharmacy.in/medicine/hisone-20mg-tablet
• Medkart, Hisone 20 mg Tablet 10’s (food and dosing guidance): https://www.medkart.in/gu/order-medicine/hisone-20mg-tablet-10s

Disclaimer

This information is for general education and does not replace advice from a qualified doctor or pharmacist. Use Hisone 20 mg Tablets only under a valid prescription and follow the dose and taper your doctor sets.