What is Truvada?

Published: 28, Dec 2024

What is Truvada?

Truvada is a medication used to prevent and treat HIV. It is a combination of two drugs: emtricitabine and tenofovir disoproxil fumarate. It works by blocking HIV from replicating, helping protect the immune system. 

Truvada is widely known as a PrEP (Pre-Exposure Prophylaxis) medication, which means it helps people who are at high risk avoid contracting HIV. 

It can also be part of a treatment plan for those living with HIV.


How Does Truvada Work?

Truvada blocks enzymes that HIV needs to multiply in the body. If taken daily, it can reduce the risk of HIV transmission significantly. 

For people at risk, such as those with an HIV-positive partner, this medication is life-changing.


Truvada Uses

  • HIV Prevention (PrEP): Truvada helps prevent HIV in people at high risk.
  • HIV Treatment: It is also part of combination therapies for people who already have HIV.
  • Post-Exposure Prophylaxis (PEP): In some cases, Truvada may be used after potential exposure to HIV.


Truvada Dosage

The amount of Truvada you should take depends on your weight and doctor's prescription. Always follow your doctor’s instructions for the right dose.

Each Truvada tablet has two main medicines: emtricitabine and tenofovir disoproxil fumarate. There are four tablet strengths available:

  • 100 mg emtricitabine / 150 mg tenofovir
  • 133 mg emtricitabine / 200 mg tenofovir
  • 167 mg emtricitabine / 250 mg tenofovir
  • 200 mg emtricitabine / 300 mg tenofovir


Truvada Dosage for HIV Treatment

The dosage of Truvada depends on a person’s weight.

WeightTablet StrengthDosage
77 lbs (35 kg) or more200 mg emtricitabine / 300 mg tenofovirTake 1 tablet once daily
62–75 lbs (28–34 kg)167 mg emtricitabine / 250 mg tenofovirTake 1 tablet once daily
48–59 lbs (22–27 kg)133 mg emtricitabine / 200 mg tenofovirTake 1 tablet once daily
37–46 lbs (17–21 kg)100 mg emtricitabine / 150 mg tenofovirTake 1 tablet once daily


Generic Truvada

Generic Truvada contains the same active ingredients but costs less. Generics are FDA-approved and offer the same efficacy. This makes HIV prevention more accessible to people around the world.


Side Effects of Truvada

Like any medication, Truvada can cause side effects.

 Common side effects:

  • Nausea
  • Headaches
  • Fatigue
  • vomiting
  • Diarrhea
  • High cholesterol
  • Dizziness
  • Sinus infection
  • Rash
  • Headache
  • Insomnia 
  • Sore throat
  • Respiratory infections
  • Serious side effects:
  • Kidney damage
  • Liver problems. 
  • Depression. 
  • Bone loss
  • Lactic acidosis
  • Worsening of hepatitis B virus infection

If you experience severe side effects, talk to your doctor immediately.

Long-Term Effects of Truvada

Some people worry about Truvada's long-term effects. While it’s generally safe, prolonged use may affect kidney function or weaken bones. Regular check-ups with your doctor can help catch any issues early.


Truvada Cost and Accessibility

The cost of Truvada, especially the brand-name version, can be high. However, generic Truvada offers a more affordable alternative. Many programs also help make PrEP accessible to those in need.


The test required before stating Truvada : 

Test TypePurpose
Hepatitis B Virus TestTo check for an existing hepatitis B infection.
Kidney Function TestTo ensure healthy kidneys, Truvada can affect kidney performance.
Liver Function TestTo identify any liver problems before starting the medication.
HIV Test (for PrEP)To confirm that you do not have HIV before using Truvada for PrEP.
HIV and Immune Cell CountTo assess the level of HIV infection and immune strength (for HIV treatment only).



Common FAQ’S

What is Truvada used for? 

 It’s used for HIV prevention (PrEP) and treatment in combination with other drugs.


Is there a generic version of Truvada?

 Yes, generic Truvada offers the same benefits at a lower price.


Can Truvada harm the kidneys?

 Long-term use may affect kidney health. Regular check-ups are recommended.


how long does it take for Truvada to work

Truvada takes about 7 to 20 days of daily use to reach full effectiveness


Can Truvada be used after exposure to HIV?

 Yes, it may be part of a PEP regimen but it must be started within 72 hours of exposure.
                                                                     

Conclusion

Truvada has revolutionized HIV prevention and treatment, offering hope and protection for millions. While concerns about side effects and costs exist, generics and medical advancements continue to improve access.
 Always consult a healthcare provider to determine if Truvada is the right option.