Proluton Depot 500 Mg Injection

Description

About Proluton Depot 500 mg Injection

Proluton Depot 500 mg Injection contains 500 mg of hydroxyprogesterone caproate in a 2 ml vial. It is a progestogen — a synthetic form of the hormone progesterone — formulated as a long-acting (depot) intramuscular injection, and is given by a doctor or nurse rather than self-administered.

How it works

Progesterone is the hormone that prepares and maintains the lining of the womb and keeps the muscle of the uterus quiet. Hydroxyprogesterone caproate acts in the same way but is released slowly from the injection site over days, so a single dose keeps hormone levels steady far longer than progesterone taken by mouth.

What it is used for

Hydroxyprogesterone caproate is prescribed by a specialist in pregnancy-related and gynaecological conditions, and the decision depends on the diagnosis and on national guidance. Its use to reduce the risk of preterm birth has been reassessed in recent years: the licence for that indication was withdrawn in the United States in 2023 after a confirmatory trial did not show benefit, and practice differs between countries. Your doctor will explain why it is being offered in your case.

Important: this is an injection, not a tablet

This product is supplied as a vial for intramuscular injection and is given by a healthcare professional. It is not taken by mouth.

Safety and monitoring

Tell your doctor before treatment about any history of blood clots, stroke or heart disease, liver problems, breast or other hormone-sensitive cancer, or unexplained vaginal bleeding, as these may make it unsuitable. Seek medical attention promptly for pain or swelling in a leg, chest pain, sudden breathlessness, a severe headache or changes in vision. Pain, swelling, itching or a lump at the injection site is common. Tell your doctor about every other medicine you take.

Prescription and storage

A prescription from your healthcare provider is required. The injection is stored and handled according to the pack instructions, away from light, and out of the reach of children.