Flutopic 10 Gm

What is Flutopic 10 Gm?

Flutopic 10 Gm is a topical corticosteroid cream containing Fluticasone Propionate, used for the short-term treatment of inflammatory and pruritic skin conditions in adults and children. Fluticasone propionate is a potent synthetic glucocorticoid that reduces redness, swelling, itching, and skin irritation caused by inflammatory dermatological conditions such as eczema, psoriasis, and contact dermatitis.

Each tube of Flutopic 10 Gm contains Fluticasone Propionate 0.05% cream — a standard concentration used for inflammatory skin conditions on the body (excluding the face, groin, and axillae where lower-potency preparations are preferred). The product is supplied in a 10 gram tube, providing sufficient quantity for a targeted short course of treatment.

Flutopic is manufactured by Systopic Laboratories Pvt. Ltd., an Indian specialty pharmaceutical company focused on topical and dermatological preparations alongside a range of systemic medicines.

Prescription only (Rx). Use externally only. Do not apply to the face, eyes, or broken skin unless specifically directed by your doctor.

Composition

About Systopic Laboratories Pvt. Ltd.

Systopic Laboratories Pvt. Ltd. is an Indian pharmaceutical company headquartered in Delhi, specialising in topical and dermatological preparations alongside a range of systemic medicines. The company manufactures branded generic medicines distributed across India and international markets, with product quality conforming to Indian Pharmacopoeia (IP) and GMP standards. Systopic’s portfolio covers dermatological, anti-infective, and specialty formulations. Flutopic is Systopic’s branded formulation of Fluticasone Propionate, one of the most widely prescribed topical corticosteroids for inflammatory skin conditions.

How Fluticasone Propionate Works

Fluticasone propionate is a synthetic, highly selective glucocorticoid receptor agonist with potent anti-inflammatory activity. When applied topically, it exerts its effects locally within the skin through several mechanisms:

• Glucocorticoid receptor binding: Fluticasone propionate binds to cytoplasmic glucocorticoid receptors within keratinocytes and immune cells in the skin with very high affinity — among the highest of any topical corticosteroid. The receptor-drug complex translocates to the nucleus and modulates gene transcription.
• Cytokine suppression: Transactivation and transrepression of inflammatory gene targets suppresses the production of pro-inflammatory cytokines (IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, TNF-α, interferon-gamma) and chemokines that mediate the inflammatory cascade in eczema and other dermatoses.
• Arachidonic acid pathway inhibition: Fluticasone induces lipocortin-1 (annexin-1), which inhibits phospholipase A2 and thereby reduces production of arachidonic acid metabolites — prostaglandins, leukotrienes, and thromboxanes — all of which contribute to vasodilation, oedema, and itch in inflammatory skin disease.
• Mast cell stabilisation: Reduces mast cell mediator release, contributing to reduced itch, urticaria, and acute inflammatory responses.
• Vasoconstriction: Topical corticosteroids reduce cutaneous vasodilation (blanching effect), which reduces the erythema, warmth, and oedema of inflamed skin.

The net result is a reduction in the cardinal signs of skin inflammation: redness (erythema), swelling (oedema), itch (pruritus), and scaling. Fluticasone propionate 0.05% is classified as a potent topical corticosteroid — effective for most inflammatory dermatoses on the body while carrying a lower risk of systemic absorption compared to very potent agents (e.g., clobetasol propionate 0.05%).

Indications: When Is Flutopic 10 Gm Prescribed?

Fluticasone propionate cream is indicated for the symptomatic treatment of steroid-responsive inflammatory skin conditions in adults and children:

• Atopic dermatitis (eczema): The most common indication. Reduces flare-related redness, itch, lichenification, and weeping. Applied during flares on the body (not the face in children); used intermittently as part of a maintenance strategy (proactive therapy) to prevent recurrence.
• Psoriasis: Reduces plaque erythema, scaling, and thickness on the body. Often combined with vitamin D analogues for synergistic effect; not a first-line face treatment.
• Contact dermatitis (allergic and irritant): Reduces the inflammatory response following contact with allergens or irritants, relieving itch, blistering, and redness.
• Seborrheic dermatitis: Used on the body for inflammatory seborrhoeic plaques; lower-potency agents are preferred on the face and scalp.
• Lichen simplex chronicus: Thick, leathery, itchy skin plaques on the nape, shins, and ankles resulting from chronic scratching; potent corticosteroids are often required for adequate control.
• Discoid eczema (nummular dermatitis): Coin-shaped eczematous plaques on the limbs and trunk.
• Insect bite reactions: Short-term use to reduce localised swelling and intense itch from insect bites.

Flutopic 10 Gm is for use on the body. Do not apply to the face, scalp, genitals, or axillae without specific medical direction, as these sites absorb topical corticosteroids more readily and are at higher risk of local side effects such as skin atrophy. Topical corticosteroids treat symptoms; they do not cure the underlying condition. Treatment should be combined with appropriate emollient (moisturiser) use and avoidance of triggers.

Dosage and Application

• Apply a thin layer to the affected area(s) of skin once or twice daily, as directed by your doctor.
• Gently rub into the skin until absorbed. The “fingertip unit” (FTU) guide is helpful — one FTU (the amount squeezed from a tube nozzle to cover one adult fingertip) treats an area approximately the size of two adult palms.
• Do not apply under occlusive dressings (bandages, cling film) unless instructed by your doctor — occlusion significantly increases absorption and side effect risk.
• Wash hands after application, unless hands are the treated area.
• Do not apply near the eyes — avoid accidental contact with mucous membranes and eyes; if contact occurs, rinse immediately with water.
• Use for the shortest effective course — typically 2–4 weeks for acute flares. Do not use continuously for prolonged periods (months) without review.
• Apply emollient (moisturiser) alongside treatment; apply emollient first and wait 30 minutes before applying the corticosteroid cream, or apply the emollient after at a suitable interval.

Special Populations

Children

Children have a larger body surface area relative to weight than adults, making them more susceptible to systemic absorption of topical corticosteroids. Flutopic 10 Gm (Fluticasone Propionate 0.05%) should be used with particular care in children — use the minimum amount needed, avoid extended application areas, and use for the shortest possible course. Do not apply to the face, nappy/diaper area, or under occlusive clothing in children. A lower-concentration preparation (0.005% cream or lotion) may be more appropriate for children, particularly on delicate areas. A paediatrician or paediatric dermatologist should be involved in managing chronic inflammatory skin conditions in children.

Pregnancy and Breastfeeding

Topical corticosteroids are not systemically absorbed in significant amounts at normal doses, but extensive or prolonged application can result in measurable systemic levels. In pregnancy, potent topical corticosteroids should be used sparingly and for the shortest necessary duration, and avoided over large areas or under occlusion. If breastfeeding, do not apply to the breast or nipple area, and apply to the minimum area necessary. Discuss use during pregnancy or breastfeeding with your doctor.

Elderly Patients

Elderly skin is more prone to atrophy. Use the minimum effective amount and duration in elderly patients; monitor for skin thinning, particularly over areas prone to trauma.

Precautions

• Do not use on infected skin: Topical corticosteroids mask the signs of skin infection and can worsen bacterial, fungal, or viral skin infections. If skin infection is present or suspected (weeping, crusting, worsening redness, pustules), consult your doctor before applying Flutopic — an appropriate antimicrobial may be needed first or in combination.
• Do not use on the face (unless directed): The face is a sensitive area prone to side effects of potent corticosteroids — acne, rosacea-like dermatitis, perioral dermatitis, telangiectasia (broken blood vessels), and skin thinning. If you are directed to use a topical steroid on the face, only low-potency preparations should normally be used.
• Skin atrophy: Prolonged use of potent corticosteroids causes thinning of the skin (skin atrophy), striae (stretch marks), and telangiectasia. These changes can be irreversible. Use the minimum effective course.
• HPA axis suppression: Large-area application, prolonged use, or use under occlusion can lead to enough systemic absorption to suppress the hypothalamic-pituitary-adrenal (HPA) axis — particularly in children. Signs include fatigue, weakness, and susceptibility to illness.
• Tachyphylaxis: Continuous daily use may lead to reduced responsiveness. If the cream appears to stop working, consult your doctor rather than increasing frequency of use.
• Avoid eyes: Prolonged periocular application of topical corticosteroids is associated with raised intraocular pressure and glaucoma. Do not apply near the eyes.

Contraindications

Flutopic 10 Gm must not be used in patients with:

• Known hypersensitivity to fluticasone propionate or any excipient in the formulation
• Untreated bacterial, fungal, or viral infections of the skin (including impetigo, tinea infections, herpes simplex, varicella)
• Rosacea or perioral dermatitis (topical corticosteroids worsen these conditions)
• Acne vulgaris
• Perianal or genital pruritus
• Primary cutaneous tuberculosis

Side Effects

Side effects are uncommon with appropriate short-term use on intact, non-facial skin. They are more likely with prolonged use, large-area application, occlusion, or use in sensitive sites.

Common (at the application site)

• Mild burning or stinging sensation on first application
• Skin dryness or irritation
• Itching (may worsen transiently on initial application)
• Skin redness at the application site

With Prolonged or Inappropriate Use

• Skin atrophy (thinning, increased fragility, easy bruising)
• Striae (stretch marks) — more common in skin folds and occluded areas
• Telangiectasia (fine visible blood vessels on the skin surface)
• Perioral or periorbital dermatitis from face application
• Acneiform eruptions
• Hypopigmentation (loss of skin colour) — more noticeable in darker skin tones
• Contact dermatitis to the formulation (rare; may manifest as worsening rather than improvement)
• HPA axis suppression (with extensive application or occlusion) — typically reversible on stopping

Stop Use and Seek Medical Advice If

• The condition worsens or fails to improve after 2–4 weeks
• Signs of skin infection develop (spreading redness, pus, crusting, pain)
• The skin becomes visibly thinner or develops bruising easily
• Systemic symptoms appear (fatigue, weakness, weight gain around the face or trunk — potential HPA suppression)

Storage Instructions

• Store below 25°C (77°F) in a cool, dry place away from heat and humidity.
• Do not freeze.
• Keep the tube tightly closed when not in use.
• Keep out of the reach of children.
• Do not use after the expiry date printed on the tube or carton.

Related Products

Patients managing respiratory conditions treated with inhaled fluticasone should see the Beclate 200 Mcg Inhaler (Beclomethasone dipropionate inhaled corticosteroid for asthma) and Beclate 400 Mcg Capsules for reference. For other respiratory medicines available on Indogenmed, browse the full range of products across our catalogue.

Frequently Asked Questions (FAQs)

1. What skin conditions is Flutopic (Fluticasone Propionate cream) used for?

Flutopic 10 Gm is used for inflammatory skin conditions that respond to topical corticosteroid treatment. The most common indications are atopic dermatitis (eczema), psoriasis, contact dermatitis, seborrheic dermatitis on the body, and lichen simplex chronicus. It is classified as a potent topical corticosteroid and is effective for most body-site inflammatory dermatoses. It is not appropriate for use on the face, groin, or other sensitive areas without specific medical direction.

2. How long should I use Flutopic 10 Gm?

For most acute inflammatory flares, Flutopic is used for 2–4 weeks until the skin improves. Prolonged continuous use is associated with skin atrophy (skin thinning) and other local side effects, and should be avoided. If your condition requires longer-term management, your doctor may recommend intermittent or “proactive” therapy — applying the cream 2–3 times per week to previously affected areas to prevent flares — rather than daily continuous use. Do not continue using the cream beyond the prescribed course without medical review.

3. Can I use Flutopic on my face?

No — Fluticasone propionate 0.05% cream is a potent corticosteroid and should not routinely be applied to the face. Facial skin is thinner and more sensitive, absorbs corticosteroids more readily, and is at higher risk of side effects including thinning, telangiectasia (visible broken blood vessels), steroid-induced acne, and rosacea-like dermatitis. If you have inflammatory skin conditions on your face (such as eczema or seborrheic dermatitis), your doctor will likely prescribe a lower-potency preparation that is appropriate for facial use. If you have been specifically instructed to apply this to the face, follow your doctor’s instructions exactly and use it for the shortest possible time.

4. Can I apply Flutopic under an occlusive dressing or bandage?

Only if specifically directed by your doctor. Occlusive dressings (covering the cream with a bandage, cling film, or tight clothing) greatly increase absorption of the corticosteroid into the skin and bloodstream, raising both the effectiveness and the risk of local and systemic side effects. Occlusion may be used intentionally by dermatologists for certain thick, resistant plaques — but this should only be done under medical supervision and for limited periods.

5. Is Flutopic safe during pregnancy?

Topical fluticasone propionate has limited systemic absorption when used correctly on small areas for short periods. However, given that potent topical corticosteroids can be absorbed into the bloodstream with extensive use, they are generally recommended to be used during pregnancy only when clearly needed and for the minimum effective amount and duration. If you are pregnant or planning to become pregnant, inform your doctor before using Flutopic. As a general precaution, do not apply over large areas or use under occlusion during pregnancy.

References

1. NHS (UK). Fluticasone skin cream and ointment. Available at: https://www.nhs.uk/medicines/fluticasone-skin-cream-and-ointment/ [Accessed November 2026].
2. MedlinePlus (US National Library of Medicine). Fluticasone Topical. Available at: https://medlineplus.gov/druginfo/meds/a605001.html [Accessed November 2026].
3. US National Library of Medicine, DailyMed. Fluticasone Propionate Cream 0.05% — Drug Label Information. Available at: https://dailymed.nlm.nih.gov/dailymed/ [Accessed November 2026].
4. British National Formulary (BNF). Fluticasone Propionate — Topical corticosteroids: prescribing notes. Available at: https://bnf.nice.org.uk/ [Accessed November 2026].

Disclaimer: This information is for educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Flutopic 10 Gm is a prescription topical corticosteroid. Apply only as directed by your doctor. Do not use on infected skin, the face, or under occlusion without medical direction. Prolonged use carries a risk of skin thinning and other local side effects. If your condition worsens or does not improve, consult your doctor promptly.