Glez 2.5 Mg Tablets

Description

Glez 2.5 mg Tablets (Glipizide 2.5 mg)

Glez 2.5 mg Tablets contains glipizide 2.5 mg, a sulfonylurea oral antidiabetic medicine. It is prescribed for adults with type 2 diabetes mellitus when diet and exercise alone cannot control blood sugar. The product is manufactured by Aristo Pharmaceuticals Pvt Ltd in India. It is a prescription medicine and should be taken only under a doctor’s supervision.

Composition

Product Details

Glez is sold in several strengths, including 2.5 mg, 5 mg, 7.5 mg and 10 mg tablets, so the strength printed on the pack must match the prescription. The 2.5 mg tablet is the lowest strength and is usually the starting dose for people who are new to sulfonylurea treatment or who are at higher risk of low blood sugar. Packs are typically a strip of 10 tablets, but pack sizes vary by supplier.

Mechanism of Action

Glipizide lowers blood glucose by stimulating the beta cells of the pancreas to release insulin. It also reduces the amount of glucose the liver releases and makes the body’s tissues more sensitive to insulin. Because it depends on working beta cells to make insulin, it is not effective in type 1 diabetes.

Indications

Glez 2.5 mg is used for the treatment of type 2 diabetes mellitus, either alone or together with diet, exercise and other diabetes medicines. It can be used alongside insulin when the doctor prescribes it. The doctor selects the dose based on HbA1c results, kidney and liver function and the response to previous treatment.

Dosage and Administration

Take the tablet exactly as prescribed, usually once daily before breakfast, about 30 minutes before food. Swallow it with a glass of water and take it at the same time each day. Glipizide is generally taken before meals because food can slow its absorption. The dose is usually started low and increased gradually according to blood sugar readings. Never take extra tablets to make up for a missed dose, and do not stop the medicine without medical advice. Regular blood sugar checks and periodic HbA1c tests help the doctor confirm that the dose is still right.

Special Populations

Older adults: Older patients and those with reduced kidney or liver function are more prone to low blood sugar, so a lower dose is usually used and they are monitored more closely.

Kidney and liver disease: Glipizide should be used with caution in people with liver disease, and dose adjustment may be needed. Patients with kidney problems should tell the doctor, because the drug is cleared by the liver and the dose may need changing.

Pregnancy and breastfeeding: The safety of glipizide during pregnancy has not been established. Women who are pregnant, planning pregnancy or breastfeeding should discuss the treatment with their doctor, since insulin is usually used to manage diabetes in pregnancy.

Children: Use in children is not established for this product, so paediatric use should be decided by a specialist.

Precautions

Glipizide can cause hypoglycaemia (low blood sugar), particularly if meals are skipped or delayed, if alcohol is taken, or if the dose is higher than needed. Carry a fast-acting sugar source at all times. Alcohol should be used with caution, because it can cause dangerous drops in blood sugar. Tell your doctor about any illness, fever, surgery or injury, since these can change blood sugar levels. Regular blood sugar and HbA1c monitoring is important. Glipizide can also affect laboratory test results, so inform the staff performing tests that you take it. Weight gain is a recognised effect, so report it if it persists.

Contraindications

Do not use Glez 2.5 mg if you are allergic to glipizide or to other sulfonylureas. It should not be used in type 1 diabetes, in diabetic ketoacidosis, or in people with severe liver disease without specialist advice.

Side Effects

Common side effects include minor stomach upset, headache, dizziness and weight gain. Low blood sugar can cause shakiness, sweating, rapid heartbeat, hunger, confusion or irritability. Rarer effects include skin rash, sensitivity to sunlight and changes in blood counts. Seek urgent medical help for severe low blood sugar that does not respond to sugar, fainting, a rash with swelling, or yellowing of the skin or eyes.

Drug Interactions

Several medicines can increase the blood-sugar-lowering effect of glipizide, including other diabetes medicines, insulin, certain antibiotics and some pain relievers. Beta-blockers can mask the warning signs of low blood sugar. Some medicines, including corticosteroids and diuretics, can raise blood sugar and reduce the effect of glipizide. Tell your doctor and pharmacist about every prescription, over-the-counter and herbal product you use before starting treatment.

Storage

Store the tablets below 30 degrees Celsius, in the original pack, away from excess heat, moisture and direct sunlight. Keep them out of the reach of children and pets. Do not use the tablets after the expiry date printed on the pack.

Frequently Asked Questions

Is glipizide the same as metformin?
No. Glipizide is a sulfonylurea that stimulates insulin release, while metformin is a biguanide that mainly reduces glucose production in the liver.

Can I take it with insulin?
Yes, if your doctor prescribes both. The doctor will adjust the doses and monitor blood sugar closely.

Can I take it with food?
It is usually taken about 30 minutes before a meal, not with it, because food can slow its absorption. Ask your doctor if you have any doubt about your timing.

What should I do if I miss a dose?
Take it when you remember, unless it is nearly time for the next dose. Do not double the dose.

References

• Apollo Pharmacy, Glez 5 mg Tablet and Glez 2.5 mg Tablet substitute information (glipizide composition, type 2 diabetes use, dosing timing): https://www.apollopharmacy.in/medicine-substitute/glez-2-5mg-tablet
• 1mg, Glez 2.5 mg Tablet information (pregnancy and liver cautions, alcohol caution): https://www.1mg.com/drugs/glez-2.5mg-tablet-247355
• 1mg, Glez product information (glipizide strengths, sulfonylurea class, hypoglycaemia warnings): https://1mg.com/medicines/glez-28077

Disclaimer

This information is for general education and does not replace advice from a qualified doctor or pharmacist. Use Glez 2.5 mg Tablets only under a valid prescription and follow the dose your doctor sets.