AVAILABLE MEDICINE FOR Aprepitant


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Introduction to Aprepitant

Aprepitant is an antiemetic medication for the prevention of nausea and vomiting caused by chemotherapy and surgery. It belongs to a class of drugs referred to as neurokinin-1 receptor antagonists that exhibit their antiemetic action through blockade of the actions of substance P-a neuropeptide involved in the vomiting reflex. Aprepitant is also very commonly administered together with other antiemetic agents, which enhances its action. It is usually administered orally before chemotherapy and can also be prescribed for nausea after surgery. Fatigue, dizziness and GI disturbances are common side effects. Drug interactions:

The patient should be aware of drug interactions because aprepitant strongly influences the metabolism of a variety of drugs through its effect on liver enzymes. Doses: Dosage depends on the chemotherapy regime and individual need. It is essential that the patient communicate about other medications that are being taken currently with their health care provider to eliminate any potential medication interactions. Aprepitant can improve the quality of life amongst patients who have been undertaking cancer treatment by approving nausea and vomiting, therefore allowing the patient to go on with their scheduled treatments. The patients should also follow dosing information correctly provided by the health professional and address unusual symptoms encountered during the treatment process.