AVAILABLE MEDICINE FOR Emtricitabine


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Effoday 300 mg/600 mg Tablet Effoday 300 mg/600 mg Tablet

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Ricovir EM Tablets Ricovir EM Tablets

$16

$16

Ricovir EM Tablets 2 Bottle Supply Ricovir EM Tablets 2 Bottle Supply

$30 $40

$30 $40

Ricovir EM Tablets 3 Bottle Supply Ricovir EM Tablets 3 Bottle Supply

$40 $50

$40 $50

Ricovir EM Tablets 4 Bottle Supply Ricovir EM Tablets 4 Bottle Supply

$55 $80

$55 $80

Ricovir EM Tablets 6 Bottle Supply Ricovir EM Tablets 6 Bottle Supply

$80 $100

$80 $100

Spegra Tablet Spegra Tablet

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Taficita Tablet Taficita Tablet

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Tenof Em - 1 Bottle Supply (30 Pills) Tenof Em - 1 Bottle Supply (30 Pills)

$21 $30

$21 $30

Tenof Em - 2 Bottles Supply (60 Tablets) Tenof Em - 2 Bottles Supply (60 Tablets)

$42 $90

$42 $90

Tenof Em - 3 Bottles Supply (90 Tablets) Tenof Em - 3 Bottles Supply (90 Tablets)

$63 $90

$63 $90

Tenof Em - 4 Bottles Supply (120 Tablets) Tenof Em - 4 Bottles Supply (120 Tablets)

$80 $120

$80 $120

Tenof Em - 6 Bottles Supply (180 Tablets) Tenof Em - 6 Bottles Supply (180 Tablets)

$120 $180

$120 $180

Tenvir Em - 1 Bottle Supply (30 Tablets) Tenvir Em - 1 Bottle Supply (30 Tablets)

$20 $40

$20 $40

Tenvir Em - 2 Bottles Supply (60 Tablets) Tenvir Em - 2 Bottles Supply (60 Tablets)

$40 $70

$40 $70

Tenvir Em - 3 Bottle Supply Tenvir Em - 3 Bottle Supply

$60 $120

$60 $120

Tenvir Em - 4 Bottles Supply (120 Tablets) Tenvir Em - 4 Bottles Supply (120 Tablets)

$80 $130

$80 $130

Tavin EM Tablet Tavin EM Tablet

Viraday Tablets Viraday Tablets


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Introduction to Emtricitabine

Emtricitabine is an important drug in the fight against HIV-1, which affects over 38 million people worldwide. As a nucleoside reverse transcriptase inhibitor (NRTI). It acts like a guard in the body, blocking reverse transcriptase, an enzyme that the virus needs to replicate. This blockage stops the virus from making copies of itself and spreading.

With effective treatments like Emtricitabine, many patients have experienced significant health improvements. In clinical studies, over 90% of patients taking Emtricitabine with other antiretrovirals achieved undetectable viral loads, meaning the virus was suppressed to levels that standard tests could not find. This control boosts immune function and greatly lowers the risk of HIV-related illnesses.

How it Works ? 

Emtricitabine targets the reverse transcriptase enzyme that HIV uses to turn its RNA into DNA. By blocking this enzyme, Emtricitabine stops the virus from making DNA. It gets added to the growing viral DNA chain, which causes the chain to end too soon. This stops the virus from inserting its DNA into the host cell's genome. 

As a result, HIV replication stops, and the viral load in the body decreases significantly. This process is essential for managing HIV-1 infection and improving health when used with other antiretroviral drugs.

Dosage and Administration.

Standard Dosage - The usual dose of Emtricitabine is 200 mg, taken once a day. This dose is often used with other HIV medications.

Administration Routes - Emtricitabine comes in tablet form and as a liquid. You can take the tablet with or without food.

Special Instructions

  • Take Emtricitabine at the same time each day to keep the drug levels steady in your body. 

  • If you miss a dose, take it as soon as you remember. 

  • Do not take two doses at once to make up for a missed one, as this can cause side effects.

Effectiveness

Clinical studies show that Emtricitabine is very effective in treating HIV-1 infection. It significantly reduces viral load and increases CD4 cell counts in patients. 

In Clinical trials, more than 90% of patients achieved and maintained viral suppression after 48 weeks of treatment. Emtricitabine is often compared to other antiretroviral drugs like tenofovir and lamivudine, and it is recognized for its strong effectiveness and mild side effects.

FDA Approval

The U.S. Food and Drug Administration (FDA) approved Emtricitabine in July 2003 for treating HIV-1 when used with other antiretroviral drugs. It is part of fixed-dose combinations like Truvada (with tenofovir disoproxil fumarate) and Descovy (with tenofovir alafenamide). These combinations make HIV treatment easier by reducing the number of pills patients need to take and helping them stick to their treatment.

EMA and Other Global Approvals

Emtricitabine is also approved by the European Medicines Agency (EMA) and other international organizations, including Health Canada and Australia’s Therapeutic Goods Administration (TGA). This wide acceptance highlights its importance in managing HIV worldwide.

Side Effect of Emtricitabine

Common Side Effects:

  • Nausea

  • Diarrhea

  • Headache

  • Fatigue

Serious Side Effects:

  • Liver toxicity

  • Lactic acidosis

  • Skin or mucous membrane hyperpigmentation
    (Rare but requires immediate medical attention)

Management:

  • If you have severe or lasting side effects, talk to your healthcare provider.

  • Check-ups are important to spot and handle any risks.

  • Your treatment may need changes based on how you respond and any side effects you have.

Drug Interactions and Precautions

Medications to Avoid:

  • Certain antiretrovirals

  • Medications affecting renal function

  • Anticonvulsants

  • Specific antibiotics

Precautions:

  • Tell your healthcare providers about all your current medications and supplements.

  • Be careful when using Emtricitabine with drugs that affect the CYP3A4 enzyme system. 

  • Interactions can change how well Emtricitabine works and how your body processes it.

Current Research and Development


Expanded Drug Combinations 

Researchers are studying how well Emtricitabine works with newer drugs like doravirine and cabotegravir. Clinical trials, such as the COMBO study, are testing these combinations to improve HIV treatment, aiming for better viral suppression and fewer side effects.


Pre-Exposure Prophylaxis (PrEP)  

Emtricitabine is part of the Truvada and Descovy PrEP regimens, which effectively lower the risk of HIV transmission. Ongoing studies, like the DISCOVER trial, are checking its safety and effectiveness in different groups, including women and those at high risk.


Hepatitis Co-Infection

Researchers are examining how Emtricitabine helps patients with both HIV and hepatitis B or C. Studies like the RAPT and COHERE cohorts are looking at its impact on liver health and overall treatment success for these patients.


Resistance Studies

Trials like the ACTG 5303 study are exploring Emtricitabine resistance. These studies focus on how well it works against HIV strains that resist other drugs, using tests to improve treatment plans and ensure effective viral suppression.