AVAILABLE MEDICINE FOR Emtricitabine,tenofovir Alafenamide
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Introduction
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), and Tenofovir Alafenamide is a nucleotide reverse transcriptase inhibitor used in antiretroviral therapy.
Uses:
This combination is primarily used to treat HIV-1 infection and as pre-exposure prophylaxis (PrEP) to reduce the risk of HIV transmission.
How it Works:
Both drugs work by inhibiting the enzyme reverse transcriptase, which is crucial for viral replication, thereby reducing the viral load in the body.
Side Effects:
Side effects include
- nausea
- diarrhea
- headaches
- fatigue, and renal toxicity. More serious side effects include bone loss, lactic acidosis, and liver problems.
FDA Approval:
This combination was FDA-approved in 2016 for HIV treatment and PrEP.