AVAILABLE MEDICINE FOR Emtricitabine,tenofovir Alafenamide


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Introduction

Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI), and Tenofovir Alafenamide is a nucleotide reverse transcriptase inhibitor used in antiretroviral therapy.

Uses:

This combination is primarily used to treat HIV-1 infection and as pre-exposure prophylaxis (PrEP) to reduce the risk of HIV transmission.

How it Works:

Both drugs work by inhibiting the enzyme reverse transcriptase, which is crucial for viral replication, thereby reducing the viral load in the body.

Side Effects:

Side effects include 

  • nausea
  •  diarrhea
  • headaches
  • fatigue, and renal toxicity. More serious side effects include bone loss, lactic acidosis, and liver problems.

FDA Approval:

This combination was FDA-approved in 2016 for HIV treatment and PrEP.