
Brand Name | Geftinat |
Packaging Type | Bottle |
Molecule | Gefitinib |
Generic Name | Gefitinib 250mg |
Manufactured By | Natco Pharma |
Quantity | 30 Tablets |
Form | Tablet |
Country of Origin | India |
Categories | Oncology |
Introduction to Geftinat Gefitinib 250 mg Tablet
Geftinat 250mg Tablet is a medicine used to treat non-small cell lung cancer (NSCLC). It is especially helpful for patients with a specific mutation in the EGFR (epidermal growth factor receptor) gene.
Geftinat 250mg Tablet, manufactured by Natco Pharma Ltd., is a generic version of the well-known brand Iressa.
Gefitinib Medication works best for people whose cancer has spread to other parts of the body and who haven’t had cancer treatments before.
Geftinat targets the proteins that make cancer cells grow and divide, slowing down or stopping the tumor.
How Does Geftinat Work?
Gefitinib mechanism of action :
Geftinat 250 contains an active ingredient called Gefitinib, which blocks the activity of a protein called EGFR. EGFR is important for cell growth and repair, but when it is mutated, it becomes overactive and causes cancer cells to grow quickly.
Geftinat stops EGFR from working, which reduces the signals that tell cancer cells to grow and spread. This makes the drug especially effective for treating cancers with EGFR mutations, helping to control the disease, even when it has spread outside the lungs.
Uses of Geftinat 250mg
- Treat Non-Small Cell Lung Cancer (NSCLC): It works well for patients with specific EGFR mutations, making it a targeted and effective treatment option.
Dosage and How to Take Geftinat Tablet
- Take one Geftinat 250mg tablet daily or as instructed by your doctor.
- Swallow the tablet whole with water. Do not crush, chew, or break it, as it is designed to release the medicine slowly.
- Take Geftinat with or without food but try to take it at the same time every day to keep the medicine levels steady in your body.
Side Effects of Geftinat 250 mg Tablet
- Nausea and vomiting
- Diarrhea
- Loss of appetite
- Rash or dry skin
- Feeling tired
- Severe breathing problems
- Liver issues (e.g., yellowing of the skin or eyes)
- Severe diarrhea or stomach pain
- Swelling in the hands or feet
Precautions While Using Geftinat
- Do not take Geftinat Tablet if you are pregnant, as it may harm the baby.
- Avoid taking Geftinat 250mg while breastfeeding.
- Refrain from consuming alcohol, as it may increase the risk of side effects associated with Geftinat Gefitinib 250mg Tablet.
- Do not smoke while taking Geftinat, as it can reduce the effectiveness of the medicine.
- Geftinat may cause dizziness or fatigue; avoid activities that require alertness if these symptoms occur.
- Consult your doctor before taking this medication if you have liver or kidney issues.
- Avoid drinking grapefruit juice while taking Gefitinib, as it may alter the way the medicine works.
Drug Interactions
- Geftinat can interact with other medicines or foods:
- Medications: Avoid taking Geftinat with antacids, blood thinners, or other cancer drugs, as these may interfere with its effectiveness.
Warning:
Geftinat vs Iressa
Feature | Geftinat (Gefitinib 250mg) | Iressa (Gefitinib 250mg) |
Active Ingredient | Gefitinib | Gefitinib |
Drug Class | EGFR Tyrosine Kinase Inhibitor | EGFR Tyrosine Kinase Inhibitor |
Indication | Non-small cell lung cancer (NSCLC) with EGFR mutations | Non-small cell lung cancer (NSCLC) with EGFR mutations |
Mechanism of Action | Inhibits EGFR tyrosine kinase, blocking cancer growth | Inhibits EGFR tyrosine kinase, blocking cancer growth |
FDA Approval Status | Generic, not individually FDA-approved | FDA-approved as the branded version of Gefitinib |
Manufacturer | Natco Pharma Ltd. | AstraZeneca |
Cost | More affordable, widely available in generic markets | Higher cost as a branded medication |
Availability | Widely available as a generic | Available globally as a branded drug |
Unique Features | Cost-effective alternative to Iressa | Original branded version with extensive clinical trial data |